Common activation mechanism of class A GPCRs Q Zhou, D Yang, M Wu, Y Guo, W Guo, L Zhong, X Cai, A Dai, W Jang, ... Elife 8, e50279, 2019 | 414 | 2019 |
A structural view of the antibiotic degradation enzyme NDM-1 from a superbug Y Guo, J Wang, G Niu, W Shui, Y Sun, H Zhou, Y Zhang, C Yang, Z Lou, ... Protein & cell 2 (5), 384-394, 2011 | 187 | 2011 |
The newly emerged SARS-like coronavirus HCoV-EMC also has an" Achilles' heel": current effective inhibitor targeting a 3C-like protease Z Ren, L Yan, N Zhang, Y Guo, C Yang, Z Lou, Z Rao Protein & cell 4 (4), 248, 2013 | 176 | 2013 |
Crimean–Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses Y Guo, W Wang, W Ji, M Deng, Y Sun, H Zhou, C Yang, F Deng, H Wang, ... Proceedings of the National Academy of Sciences 109 (13), 5046-5051, 2012 | 118 | 2012 |
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ... Science 364 (6442), eaav7532, 2019 | 110 | 2019 |
Simplified captopril analogues as NDM-1 inhibitors N Li, Y Xu, Q Xia, C Bai, T Wang, L Wang, D He, N Xie, L Li, J Wang, ... Bioorganic & medicinal chemistry letters 24 (1), 386-389, 2014 | 96 | 2014 |
Comprehensive insights into the catalytic mechanism of middle east respiratory syndrome 3C-like protease and severe acute respiratory syndrome 3C-like protease H Wang, S He, W Deng, Y Zhang, G Li, J Sun, W Zhao, Y Guo, Z Yin, D Li, ... ACS catalysis 10 (10), 5871-5890, 2020 | 94 | 2020 |
Crystal structure of porcine reproductive and respiratory syndrome virus leader protease Nsp1α Y Sun, F Xue, Y Guo, M Ma, N Hao, XC Zhang, Z Lou, X Li, Z Rao Journal of virology 83 (21), 10931-10940, 2009 | 86 | 2009 |
A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes Y Guo, L Huang, G Zhang, Y Yao, H Zhou, S Shen, B Shen, B Li, X Li, ... Nature Communications 12 (1), 2623, 2021 | 84 | 2021 |
A widespread pathway for substitution of adenine by diaminopurine in phage genomes Y Zhou, X Xu, Y Wei, Y Cheng, Y Guo, I Khudyakov, F Liu, P He, Z Song, ... Science 372 (6541), 512-516, 2021 | 76 | 2021 |
Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center C Zhao, Z Lou, Y Guo, M Ma, Y Chen, S Liang, L Zhang, S Chen, X Li, ... Journal of virology 83 (18), 9024-9030, 2009 | 75 | 2009 |
Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 Å resolution S Dong, P Yang, G Li, B Liu, W Wang, X Liu, B Xia, C Yang, Z Lou, Y Guo, ... Protein & cell 6 (5), 351-362, 2015 | 69 | 2015 |
The crystal structures of two cuticle–degrading proteases from nematophagous fungi and their contribution to infection against nematodes L Liang, Z Meng, F Ye, J Yang, S Liu, Y Sun, Y Guo, Q Mi, X Huang, C Zou, ... The FASEB Journal 24 (5), 1391-1400, 2010 | 67 | 2010 |
miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4 Y Liu, Y Guo, H Liang, R Cheng, F Yang, Y Hong, C Zhao, M Liu, M Yu, ... Protein & cell 7 (10), 722-734, 2016 | 65 | 2016 |
Bunyamwera virus possesses a distinct nucleocapsid protein to facilitate genome encapsidation B Li, Q Wang, X Pan, I Fernández de Castro, Y Sun, Y Guo, X Tao, ... Proceedings of the National Academy of Sciences 110 (22), 9048-9053, 2013 | 59 | 2013 |
Structural perspective on the formation of ribonucleoprotein complex in negative-sense single-stranded RNA viruses H Zhou, Y Sun, Y Guo, Z Lou Trends in microbiology 21 (9), 475-484, 2013 | 58 | 2013 |
Identification of inhibitors of the antibiotic-resistance target New Delhi metallo-β-lactamase 1 by both nanoelectrospray ionization mass spectrometry and ultrafiltration … X Chen, L Li, S Chen, Y Xu, Q Xia, Y Guo, X Liu, Y Tang, T Zhang, Y Chen, ... Analytical chemistry 85 (16), 7957-7965, 2013 | 57 | 2013 |
Prediction of host - pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs T Huo, W Liu, Y Guo, C Yang, J Lin, Z Rao BMC bioinformatics 16, 1-9, 2015 | 54 | 2015 |
Crystal structure and mutagenesis analysis of chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with the inhibitor caffeine J Yang, Z Gan, Z Lou, N Tao, Q Mi, L Liang, Y Sun, Y Guo, X Huang, ... Microbiology 156 (12), 3566-3574, 2010 | 54 | 2010 |
The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation H Zhou, Y Sun, Y Wang, M Liu, C Liu, W Wang, X Liu, L Li, F Deng, ... Protein & cell 4 (6), 445-455, 2013 | 52 | 2013 |