| A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination … CR Boland, SN Thibodeau, SR Hamilton, D Sidransky, JR Eshleman, ... Cancer research 58 (22), 5248-5257, 1998 | 5139 | 1998 |
| APC, Signal transduction and genetic instability in colorectal cancer R Fodde, R Smits, H Clevers Nature reviews cancer 1 (1), 55-67, 2001 | 1219 | 2001 |
| Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial J Burn, AM Gerdes, F Macrae, JP Mecklin, G Moeslein, S Olschwang, ... The Lancet 378 (9809), 2081-2087, 2011 | 1143 | 2011 |
| Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis HF Vasen, JT Wijnen, FH Menko, JH Kleibeuker, BG Taal, G Griffioen, ... Gastroenterology 110 (4), 1020-1027, 1996 | 1077 | 1996 |
| Wnt/β-catenin signaling in cancer stemness and malignant behavior R Fodde, T Brabletz Current opinion in cell biology 19 (2), 150-158, 2007 | 998 | 2007 |
| Mutations in the APC tumour suppressor gene cause chromosomal instability R Fodde, J Kuipers, C Rosenberg, R Smits, M Kielman, C Gaspar, ... Nature cell biology 3 (4), 433-438, 2001 | 950 | 2001 |
| CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer H Ling, R Spizzo, Y Atlasi, M Nicoloso, M Shimizu, RS Redis, N Nishida, ... Genome research 23 (9), 1446-1461, 2013 | 683 | 2013 |
| A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. R Fodde, W Edelmann, K Yang, C Van Leeuwen, C Carlson, B Renault, ... Proceedings of the National Academy of Sciences 91 (19), 8969-8973, 1994 | 663 | 1994 |
| Expression of CD44 in Apc and Tcfmutant mice implies regulation by the WNT pathway VJM Wielenga, R Smits, V Korinek, L Smit, M Kielman, R Fodde, ... The American journal of pathology 154 (2), 515-523, 1999 | 643 | 1999 |
| The APC gene in colorectal cancer R Fodde European journal of cancer 38 (7), 867-871, 2002 | 592 | 2002 |
| Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance YMC Hendriks, A Wagner, H Morreau, F Menko, A Stormorken, ... Gastroenterology 127 (1), 17-25, 2004 | 510 | 2004 |
| Clinical findings with implications for genetic testing in families with clustering of colorectal cancer JT Wijnen, HFA Vasen, PM Khan, AH Zwinderman, H van der Klift, ... New England Journal of Medicine 339 (8), 511-518, 1998 | 496 | 1998 |
| Familial endometrial cancer in female carriers of MSH6 germline mutations J Wijnen, W Leeuw, H Vasen, H Klift, P Møller, A Stormorken, ... Nature genetics 23 (2), 142-144, 1999 | 494 | 1999 |
| Interplay between metabolic identities in the intestinal crypt supports stem cell function MJ Rodríguez-Colman, M Schewe, M Meerlo, E Stigter, J Gerrits, ... Nature 543 (7645), 424-427, 2017 | 472 | 2017 |
| Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling MF Kielman, M Rindapää, C Gaspar, N Van Poppel, C Breukel, ... Nature genetics 32 (4), 594-605, 2002 | 471 | 2002 |
| The ‘just-right’ signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade C Albuquerque, C Breukel, R van der Luijt, P Fidalgo, P Lage, FJM Slors, ... Human molecular genetics 11 (13), 1549-1560, 2002 | 449 | 2002 |
| Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion TC Luis, BAE Naber, PPC Roozen, MH Brugman, EFE de Haas, ... Cell stem cell 9 (4), 345-356, 2011 | 369 | 2011 |
| Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome J Burn, DT Bishop, JP Mecklin, F Macrae, G Möslein, S Olschwang, ... New England Journal of Medicine 359 (24), 2567-2578, 2008 | 365 | 2008 |
| Junk DNA and the long non-coding RNA twist in cancer genetics H Ling, K Vincent, M Pichler, R Fodde, I Berindan-Neagoe, FJ Slack, ... Oncogene 34 (39), 5003-5011, 2015 | 348 | 2015 |
| APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression KP Janssen, P Alberici, H Fsihi, C Gaspar, C Breukel, P Franken, C Rosty, ... Gastroenterology 131 (4), 1096-1109, 2006 | 345 | 2006 |
