Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5664 | 2018 |
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition J Mejlvang, M Kriajevska, C Vandewalle, T Chernova, AE Sayan, G Berx, ... Molecular biology of the cell 18 (11), 4615-4624, 2007 | 254 | 2007 |
TAp73/ΔNp73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma M Müller, T Schilling, AE Sayan, A Kairat, K Lorenz, ... Cell Death & Differentiation 12 (12), 1564-1577, 2005 | 231 | 2005 |
SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer AE Sayan, TR Griffiths, R Pal, GJ Browne, A Ruddick, T Yagci, R Edwards, ... Proceedings of the National Academy of Sciences 106 (35), 14884-14889, 2009 | 226 | 2009 |
Exosomal microRNAs (exomiRs): Small molecules with a big role in cancer R Bhome, F Del Vecchio, GH Lee, MD Bullock, JN Primrose, AE Sayan, ... Cancer letters 420, 228-235, 2018 | 221 | 2018 |
p73 induces apoptosis by different mechanisms S Ramadan, A Terrinoni, MV Catani, AE Sayan, RA Knight, M Mueller, ... Biochemical and biophysical research communications 331 (3), 713-717, 2005 | 193 | 2005 |
MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression MD Bullock, AE Sayan, GK Packham, AH Mirnezami Biology of the Cell 104 (1), 3-12, 2012 | 164 | 2012 |
Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression R Bhome, RW Goh, MD Bullock, N Pillar, SM Thirdborough, M Mellone, ... Aging (Albany NY) 9 (12), 2666, 2017 | 143 | 2017 |
Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression MD Bullock, KM Pickard, BS Nielsen, AE Sayan, V Jenei, M Mellone, ... Cell death & disease 4 (6), e684-e684, 2013 | 141 | 2013 |
ZEB proteins link cell motility with cell cycle control and cell survival in cancer G Browne, AE Sayan, E Tulchinsky Cell cycle 9 (5), 886-891, 2010 | 133 | 2010 |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 123 | 2023 |
Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL AE Sayan, R Stanford, R Vickery, E Grigorenko, J Diesch, K Kulbicki, ... Oncogene 31 (12), 1493-1503, 2012 | 123 | 2012 |
p53 is cleaved by caspases generating fragments localizing to mitochondria BS Sayan, AE Sayan, RA Knight, G Melino, GM Cohen Journal of Biological Chemistry 281 (19), 13566-13573, 2006 | 114 | 2006 |
A top-down view of the tumor microenvironment: structure, cells and signaling R Bhome, MD Bullock, HA Al Saihati, RW Goh, JN Primrose, AE Sayan, ... Frontiers in cell and developmental biology 3, 33, 2015 | 104 | 2015 |
Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells AE Sayan, BS Sayan, N Findikli, M Ozturk Oncogene 20 (37), 5111-5117, 2001 | 94 | 2001 |
P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis AE Sayan, BS Sayan, V Gogvadze, D Dinsdale, U Nyman, TM Hansen, ... Oncogene 27 (31), 4363-4372, 2008 | 82 | 2008 |
Regulation of p73 activity by post-translational modifications F Conforti, AE Sayan, R Sreekumar, BS Sayan Cell death & disease 3 (3), e285-e285, 2012 | 78 | 2012 |
FLASH is an essential component of Cajal bodies D Barcaroli, D Dinsdale, MH Neale, L Bongiorno-Borbone, M Ranalli, ... Proceedings of the National Academy of Sciences 103 (40), 14802-14807, 2006 | 76 | 2006 |
MicroRNA control of invasion and metastasis pathways R Sreekumar, BS Sayan, AH Mirnezami, AE Sayan Frontiers in genetics 2, 58, 2011 | 74 | 2011 |
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins Q Al-Ismaeel, CP Neal, H Al-Mahmoodi, Z Almutairi, I Al-Shamarti, ... British Journal of Cancer 121 (1), 65-75, 2019 | 59 | 2019 |