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Abhay Kotecha
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Single-particle cryo-EM at atomic resolution
T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ...
Nature 587 (7832), 152-156, 2020
7512020
Structure-based classification of tauopathies
Y Shi, W Zhang, Y Yang, AG Murzin, B Falcon, A Kotecha, M van Beers, ...
Nature 598 (7880), 359-363, 2021
5232021
GABAA receptor signalling mechanisms revealed by structural pharmacology
S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ...
Nature 565 (7740), 454-459, 2019
4932019
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs
DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ...
Nature structural & molecular biology 28 (7), 573-582, 2021
303*2021
Cryo-EM structures of amyloid-β 42 filaments from human brains
Y Yang, D Arseni, W Zhang, M Huang, S Lövestam, M Schweighauser, ...
Science 375 (6577), 167-172, 2022
2702022
Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes
SL Ilca, A Kotecha, X Sun, MM Poranen, DI Stuart, JT Huiskonen
Nature communications 6 (1), 8843, 2015
2222015
Structures of α-synuclein filaments from human brains with Lewy pathology
Y Yang, Y Shi, M Schweighauser, X Zhang, A Kotecha, AG Murzin, ...
Nature 610 (7933), 791-795, 2022
1802022
Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen
C Porta, A Kotecha, A Burman, T Jackson, J Ren, S Loureiro, IM Jones, ...
PLoS pathogens 9 (3), e1003255, 2013
1642013
Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
S Lövestam, FA Koh, B van Knippenberg, A Kotecha, AG Murzin, ...
Elife 11, e76494, 2022
1582022
High-speed fixed-target serial virus crystallography
P Roedig, HM Ginn, T Pakendorf, G Sutton, K Harlos, TS Walter, J Meyer, ...
Nature methods 14 (8), 805-810, 2017
1482017
In situ macromolecular crystallography using microbeams
D Axford, RL Owen, J Aishima, J Foadi, AW Morgan, JI Robinson, ...
Acta Crystallographica Section D: Biological Crystallography 68 (5), 592-600, 2012
1472012
Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate
F Abid Ali, L Renault, J Gannon, HL Gahlon, A Kotecha, JC Zhou, ...
Nature communications 7 (1), 10708, 2016
1292016
A supramolecular assembly mediates lentiviral DNA integration
A Ballandras-Colas, DP Maskell, E Serrao, J Locke, P Swuec, ...
Science 355 (6320), 93-95, 2017
1122017
Age-dependent formation of TMEM106B amyloid filaments in human brains
M Schweighauser, D Arseni, M Bacioglu, M Huang, S Lövestam, Y Shi, ...
Nature 605 (7909), 310-314, 2022
1102022
Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design
A Kotecha, J Seago, K Scott, A Burman, S Loureiro, J Ren, C Porta, ...
Nature structural & molecular biology 22 (10), 788-794, 2015
1102015
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
J Marsian, H Fox, MW Bahar, A Kotecha, EE Fry, DI Stuart, AJ Macadam, ...
Nature communications 8 (1), 245, 2017
1012017
CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome
JC Zhou, A Janska, P Goswami, L Renault, F Abid Ali, A Kotecha, ...
Proceedings of the National Academy of Sciences 114 (16), 4141-4146, 2017
972017
Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy
A Zeltins, J West, F Zabel, A El Turabi, I Balke, S Haas, M Maudrich, ...
npj Vaccines 2 (1), 30, 2017
962017
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
D Zhou, Y Zhao, A Kotecha, EE Fry, JT Kelly, X Wang, Z Rao, ...
Nature microbiology 4 (3), 414-419, 2019
892019
Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus
A Kotecha, Q Wang, X Dong, SL Ilca, M Ondiviela, R Zihe, J Seago, ...
Nature communications 8 (1), 15408, 2017
852017
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