Single-particle cryo-EM at atomic resolution T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ... Nature 587 (7832), 152-156, 2020 | 751 | 2020 |
Structure-based classification of tauopathies Y Shi, W Zhang, Y Yang, AG Murzin, B Falcon, A Kotecha, M van Beers, ... Nature 598 (7880), 359-363, 2021 | 523 | 2021 |
GABAA receptor signalling mechanisms revealed by structural pharmacology S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ... Nature 565 (7740), 454-459, 2019 | 493 | 2019 |
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ... Nature structural & molecular biology 28 (7), 573-582, 2021 | 303* | 2021 |
Cryo-EM structures of amyloid-β 42 filaments from human brains Y Yang, D Arseni, W Zhang, M Huang, S Lövestam, M Schweighauser, ... Science 375 (6577), 167-172, 2022 | 270 | 2022 |
Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes SL Ilca, A Kotecha, X Sun, MM Poranen, DI Stuart, JT Huiskonen Nature communications 6 (1), 8843, 2015 | 222 | 2015 |
Structures of α-synuclein filaments from human brains with Lewy pathology Y Yang, Y Shi, M Schweighauser, X Zhang, A Kotecha, AG Murzin, ... Nature 610 (7933), 791-795, 2022 | 180 | 2022 |
Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen C Porta, A Kotecha, A Burman, T Jackson, J Ren, S Loureiro, IM Jones, ... PLoS pathogens 9 (3), e1003255, 2013 | 164 | 2013 |
Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy S Lövestam, FA Koh, B van Knippenberg, A Kotecha, AG Murzin, ... Elife 11, e76494, 2022 | 158 | 2022 |
High-speed fixed-target serial virus crystallography P Roedig, HM Ginn, T Pakendorf, G Sutton, K Harlos, TS Walter, J Meyer, ... Nature methods 14 (8), 805-810, 2017 | 148 | 2017 |
In situ macromolecular crystallography using microbeams D Axford, RL Owen, J Aishima, J Foadi, AW Morgan, JI Robinson, ... Acta Crystallographica Section D: Biological Crystallography 68 (5), 592-600, 2012 | 147 | 2012 |
Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate F Abid Ali, L Renault, J Gannon, HL Gahlon, A Kotecha, JC Zhou, ... Nature communications 7 (1), 10708, 2016 | 129 | 2016 |
A supramolecular assembly mediates lentiviral DNA integration A Ballandras-Colas, DP Maskell, E Serrao, J Locke, P Swuec, ... Science 355 (6320), 93-95, 2017 | 112 | 2017 |
Age-dependent formation of TMEM106B amyloid filaments in human brains M Schweighauser, D Arseni, M Bacioglu, M Huang, S Lövestam, Y Shi, ... Nature 605 (7909), 310-314, 2022 | 110 | 2022 |
Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design A Kotecha, J Seago, K Scott, A Burman, S Loureiro, J Ren, C Porta, ... Nature structural & molecular biology 22 (10), 788-794, 2015 | 110 | 2015 |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine J Marsian, H Fox, MW Bahar, A Kotecha, EE Fry, DI Stuart, AJ Macadam, ... Nature communications 8 (1), 245, 2017 | 101 | 2017 |
CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome JC Zhou, A Janska, P Goswami, L Renault, F Abid Ali, A Kotecha, ... Proceedings of the National Academy of Sciences 114 (16), 4141-4146, 2017 | 97 | 2017 |
Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy A Zeltins, J West, F Zabel, A El Turabi, I Balke, S Haas, M Maudrich, ... npj Vaccines 2 (1), 30, 2017 | 96 | 2017 |
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2 D Zhou, Y Zhao, A Kotecha, EE Fry, JT Kelly, X Wang, Z Rao, ... Nature microbiology 4 (3), 414-419, 2019 | 89 | 2019 |
Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus A Kotecha, Q Wang, X Dong, SL Ilca, M Ondiviela, R Zihe, J Seago, ... Nature communications 8 (1), 15408, 2017 | 85 | 2017 |