Drug repositioning for orphan diseases D Sardana, C Zhu, M Zhang, RC Gudivada, L Yang, AG Jegga Briefings in bioinformatics 12 (4), 346-356, 2011 | 269 | 2011 |
Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death X Zhang, X Wang, H Zhu, C Zhu, Y Wang, WT Pu, AG Jegga, GC Fan Journal of molecular and cellular cardiology 49 (5), 841-850, 2010 | 211 | 2010 |
The orphan disease networks M Zhang, C Zhu, A Jacomy, LJ Lu, AG Jegga The American Journal of Human Genetics 88 (6), 755-766, 2011 | 78 | 2011 |
RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis M Zelic, F Pontarelli, L Woodworth, C Zhu, A Mahan, Y Ren, M LaMorte, ... Cell reports 35 (6), 2021 | 72 | 2021 |
Genome‐wide association mapping of natural variation in odour‐guided behaviour in Drosophila EB Brown, JE Layne, C Zhu, AG Jegga, SM Rollmann Genes, Brain and Behavior 12 (5), 503-515, 2013 | 31 | 2013 |
A vertex similarity-based framework to discover and rank orphan disease-related genes C Zhu, A Kushwaha, K Berman, AG Jegga BMC systems biology 6, 1-9, 2012 | 26 | 2012 |
Computational approaches for human disease gene prediction and ranking C Zhu, C Wu, BJ Aronow, AG Jegga Systems Analysis of Human Multigene Disorders, 69-84, 2013 | 22 | 2013 |
Correction of cilia structure and function alleviates multi-organ pathology in Bardet–Biedl syndrome mice H Husson, NO Bukanov, S Moreno, MM Smith, B Richards, C Zhu, ... Human Molecular Genetics 29 (15), 2508-2522, 2020 | 12 | 2020 |
An integrative network-based approach for drug target indication expansion Y Han, C Wang, K Klinger, DK Rajpal, C Zhu PloS one 16 (7), e0253614, 2021 | 11 | 2021 |
Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform Y Han, K Klinger, DK Rajpal, C Zhu, E Teeple BMC bioinformatics 23 (1), 232, 2022 | 6 | 2022 |
Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease Risk Y Han, E Teeple, S Shankara, M Sadeghi, C Zhu, D Liu, FinnGen, ... MedRxiv, 2020.10. 16.20212944, 2020 | 5 | 2020 |
Network biology methods for drug repositioning C Zhu, C Wu, AG Jegga Post-Genomic Approaches in Drug and Vaccine Development, 115-131, 2022 | 4 | 2022 |
Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease Risk (4286) Y Han, E Teeple, S Shankara, M Sadeghi, C Zhu, D Liu, - FinnGen, ... Neurology 96 (15_supplement), 4286, 2021 | 4 | 2021 |
RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function AL Flynn, J Gans, J Escobedo, C Zhu, AM Florescu, S Shankara, ... The Journal of Immunology, 2023 | 3 | 2023 |
Integrative literature and data mining to rank disease candidate genes C Wu, C Zhu, AG Jegga Biomedical Literature Mining, 207-226, 2014 | 2 | 2014 |
Orphan diseases, bioinformatics and drug discovery AG Jegga, C Zhu, BJ Aronow Pediatric Biomedical Informatics: Computer Applications in Pediatric …, 2012 | 1 | 2012 |
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants O Castellini-Pérez, E Povedano, G Barturen, M Martínez-Bueno, ... NPJ Genomic Medicine 9 (1), 38, 2024 | | 2024 |
RIPK1 activation mediates disease progression in multiple sclerosis by driving neuroinflammatory signaling in microglia and astrocytes M Zelic, F Pontarelli, A Blazier, L Woodworth, C Zhu, A Mahan, Y Ren, ... MULTIPLE SCLEROSIS JOURNAL 29, 243-244, 2023 | | 2023 |
The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug Discovery O Castellini-Pérez, G Barturen, M Martínez-Bueno, A Iakovliev, M Kerick, ... medRxiv, 2023.01. 19.22283772, 2023 | | 2023 |
Supplementary Material Correction of cilia structure and function alleviates multi-organ pathology in Bardet-Biedl Syndrome mice H Husson, NO Bukanov, S Moreno, MM Smith, B Richards, C Zhu, ... | | |