Principles for the post-GWAS functional characterization of cancer risk loci ML Freedman, ANA Monteiro, SA Gayther, GA Coetzee, A Risch, C Plass, ... Nature genetics 43 (6), 513-518, 2011 | 518 | 2011 |
Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models S Tsai, L McOlash, K Palen, B Johnson, C Duris, Q Yang, MB Dwinell, ... BMC cancer 18, 1-13, 2018 | 354 | 2018 |
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing P Liu, C Morrison, L Wang, D Xiong, P Vedell, P Cui, X Hua, F Ding, Y Lu, ... Carcinogenesis 33 (7), 1270-1276, 2012 | 244 | 2012 |
Human papillomavirus type 16 E6 activates NF-κB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner MA James, JH Lee, AJ Klingelhutz Journal of virology 80 (11), 5301-5307, 2006 | 208 | 2006 |
RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway MA James, Y Lu, Y Liu, HG Vikis, M You Cancer research 69 (5), 2108-2116, 2009 | 127 | 2009 |
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene M You, D Wang, P Liu, H Vikis, M James, Y Lu, Y Wang, M Wang, Q Chen, ... Clinical cancer research 15 (8), 2666-2674, 2009 | 122 | 2009 |
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity H Vikis, M Sato, M James, D Wang, Y Wang, M Wang, D Jia, Y Liu, ... Cancer research 67 (10), 4665-4670, 2007 | 113 | 2007 |
Common human cancer genes discovered by integrated gene-expression analysis Y Lu, Y Yi, P Liu, W Wen, M James, D Wang, M You PloS one 2 (11), e1149, 2007 | 111 | 2007 |
Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1 Y Liu, P Liu, W Wen, MA James, Y Wang, JE Bailey-Wilson, CI Amos, ... Cancer research 69 (19), 7844-7850, 2009 | 110 | 2009 |
HPV16‐E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300 MA James, JH Lee, AJ Klingelhutz International journal of cancer 119 (8), 1878-1885, 2006 | 100 | 2006 |
Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15. 33 locus MA James, W Wen, Y Wang, LA Byers, JV Heymach, KR Coombes, ... PloS one 7 (6), e36116, 2012 | 99 | 2012 |
Cancelled operations: a 7-day cohort study of planned adult inpatient surgery in 245 UK National Health Service hospitals DJN Wong, SK Harris, SR Moonesinghe, SR Moonesinghe, DJN Wong, ... British journal of anaesthesia 121 (4), 730-738, 2018 | 98 | 2018 |
Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis MA James, H Fu, Y Liu, DR Chen, M You Molecular carcinogenesis 50 (1), 1-7, 2011 | 89 | 2011 |
Charge reversal of kaolinite by hydrolyzable metal ions: an electroacoustic study RJ Hunter, M James Clays and Clay Minerals 40 (6), 644-649, 1992 | 69 | 1992 |
Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells Y Lee, Y Wang, M James, JH Jeong, M You Molecular carcinogenesis 55 (5), 991-1001, 2016 | 68 | 2016 |
CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis MA James, HG Vikis, E Tate, AL Rymaszewski, M You Cancer research 74 (4), 1116-1127, 2014 | 68 | 2014 |
Program synthesis by type-guided abstraction refinement Z Guo, M James, D Justo, J Zhou, Z Wang, R Jhala, N Polikarpova Proceedings of the ACM on Programming Languages 4 (POPL), 1-28, 2019 | 65 | 2019 |
Effect of particle size distribution and aggregation on electroacoustic measurements of. zeta. potential M James, RJ Hunter, RW O'Brien Langmuir 8 (2), 420-423, 1992 | 65 | 1992 |
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice Y Wang, M James, W Wen, Y Lu, E Szabo, RA Lubet, M You Molecular cancer therapeutics 9 (11), 3074-3082, 2010 | 58 | 2010 |
p38γ MAPK is essential for aerobic glycolysis and pancreatic tumorigenesis F Wang, XM Qi, R Wertz, M Mortensen, C Hagen, J Evans, Y Sheinin, ... Cancer research 80 (16), 3251-3264, 2020 | 53 | 2020 |