Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic Secretome of Botrytis cinerea … R Huber, A Koval, L Marcourt, M Héritier, S Schnee, E Michellod, ... Frontiers in Chemistry 10, 881298, 2022 | 10 | 2022 |
Novel mechanism for an old drug: phenazopyridine is a kinase inhibitor affecting autophagy and cellular differentiation O Preynat-Seauve, EBV Nguyen, Y Westermaier, M Héritier, S Tardy, ... Frontiers in Pharmacology 12, 664608, 2021 | 7 | 2021 |
Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1 M Bagka, H Choi, M Héritier, H Schwaemmle, QTL Pasquer, SMG Braun, ... Nature Communications 14 (1), 3893, 2023 | 5 | 2023 |
Generation of potent antibacterial compounds through enzymatic and chemical modifications of the trans-δ-viniferin scaffold R Huber, L Marcourt, M Héritier, A Luscher, L Guebey, S Schnee, ... Scientific Reports 13 (1), 15986, 2023 | 2 | 2023 |
146P A novel allosteric oral immunotherapy small molecule modulates adenosine 2a receptor signaling and restores anti-tumor immune responses D Pejoski, C Suess, A Gouiller, M Héritier, M Boujut, S Tardy, T De Smedt, ... Immuno-Oncology and Technology 20, 2023 | | 2023 |
Target elucidation through target degradation: discovery of BET bromodomains as the target of Hedgehog Pathway Inhibitor-1 M Bagka, H Choi, M Heritier, H Schwaemmle, QTL Pasquer, SMG Braun, ... | | |
Synthesis and biological evaluation of small fragment inhibitors of TNFR1 S Pannilunghi, S Tardy, A Gouiller, M Héritier, D Pejoski, L Scapozza | | |