Structural characterization of N‐linked glycans in the receptor binding domain of the SARS‐CoV‐2 spike protein and their interactions with human lectins MP Lenza, I Oyenarte, T Diercks, JI Quintana, A Gimeno, H Coelho, ... Angewandte Chemie 132 (52), 23971-23979, 2020 | 90 | 2020 |
Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor‐Associated Mucin Glycopeptides by the Human Macrophage Galactose‐Type Lectin F Marcelo, F Garcia‐Martin, T Matsushita, J Sardinha, H Coelho, ... Chemistry–A European Journal 20 (49), 16147-16155, 2014 | 68 | 2014 |
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3 M de las Rivas, EJP Daniel, Y Narimatsu, I Compañón, K Kato, ... Nature Chemical Biology, 2020 | 61 | 2020 |
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition D Madariaga, N Martinez-Saez, VJ Somovilla, H Coelho, ... ACS chemical biology 10 (3), 747-756, 2015 | 47 | 2015 |
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences M De Las Rivas, E Lira-Navarrete, EJP Daniel, I Compañón, H Coelho, ... Nature communications 8 (1), 1959, 2017 | 42 | 2017 |
The quest for anticancer vaccines: Deciphering the fine-epitope specificity of cancer-related monoclonal antibodies by combining microarray screening and Saturation Transfer … H Coelho, T Matsushita, G Artigas, H Hinou, FJ Cañada, R Lo-Man, ... Journal of the American Chemical Society 137 (39), 12438-12441, 2015 | 41 | 2015 |
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4 M De Las Rivas, EJ Paul Daniel, H Coelho, E Lira-Navarrete, L Raich, ... ACS central science 4 (9), 1274-1290, 2018 | 39 | 2018 |
The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose‐Type Lectin A Diniz, H Coelho, JS Dias, SJ van Vliet, J Jiménez‐Barbero, F Corzana, ... Chemistry–A European Journal 25 (61), 13945-13955, 2019 | 31 | 2019 |
Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties F Cochet, FA Facchini, L Zaffaroni, JM Billod, H Coelho, A Holgado, ... Scientific reports 9 (1), 919, 2019 | 31 | 2019 |
Crystal structure of the carbohydrate recognition domain of the human macrophage galactose C-type lectin bound to GalNAc and the tumor-associated Tn antigen A Gabba, A Bogucka, JG Luz, A Diniz, H Coelho, F Corzana, FJ Cañada, ... Biochemistry 60 (17), 1327-1336, 2021 | 28 | 2021 |
Glycans in infectious diseases. A molecular recognition perspective L Unione, A Gimeno, P Valverde, I Calloni, H Coelho, S Mirabella, ... Current medicinal chemistry 24 (36), 4057-4080, 2017 | 22 | 2017 |
Structural Analysis of a GalNAc‐T2 Mutant Reveals an Induced‐Fit Catalytic Mechanism for GalNAc‐Ts M de Las Rivas, H Coelho, A Diniz, E Lira‐Navarrete, I Compañón, ... Chemistry–A European Journal 24 (33), 8382-8392, 2018 | 21 | 2018 |
Molecular Recognition Insights of Sialic Acid Glycans by Distinct Receptors Unveiled by NMR and Molecular Modeling CO Soares, AS Grosso, J Ereño-Orbea, H Coelho, F Marcelo Frontiers in Molecular Biosciences 8, 727847, 2021 | 17 | 2021 |
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling H Coelho, M Rivas, AS Grosso, A Diniz, CO Soares, RA Francisco, ... JACS Au 2 (3), 631-645, 2022 | 14 | 2022 |
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody J Macías-León, IA Bermejo, A Asín, A García-García, I Compañón, ... Chemical Communications 56 (96), 15137-15140, 2020 | 12 | 2020 |
Structural basis for the synthesis of the core 1 structure by C1GalT1 AM González-Ramírez, AS Grosso, Z Yang, I Compañón, H Coelho, ... Nature Communications 13 (1), 2398, 2022 | 11 | 2022 |
Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune‐Related Lectins CDL Lima, H Coelho, A Gimeno, F Trovão, A Diniz, JS Dias, ... Chemistry–A European Journal 27 (29), 7951-7958, 2021 | 8 | 2021 |
Co‐administration of Antimicrobial Peptides Enhances Toll‐like Receptor 4 Antagonist Activity of a Synthetic Glycolipid FA Facchini, H Coelho, SE Sestito, S Delgado, A Minotti, D Andreu, ... ChemMedChem 13 (3), 280-287, 2018 | 8 | 2018 |
Peptidomimetic β-secretase inhibitors comprising a sequence of amyloid-β peptide for Alzheimer’s disease H Vila-Real, H Coelho, J Rocha, A Fernandes, MR Ventura, CD Maycock, ... Journal of medicinal chemistry 58 (14), 5408-5418, 2015 | 8 | 2015 |
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody MP Lenza, U Atxabal, C Nycholat, I Oyenarte, A Franconetti, JI Quintana, ... JACS Au 3 (1), 204-215, 2022 | 7 | 2022 |