The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4 V Mata-Haro, C Cekic, M Martin, PM Chilton, CR Casella, TC Mitchell Science 316 (5831), 1628-1632, 2007 | 1040 | 2007 |
Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment IJ Fugier-Vivier, F Rezzoug, Y Huang, AJ Graul-Layman, CL Schanie, ... The Journal of experimental medicine 201 (3), 373-383, 2005 | 213 | 2005 |
The low-toxicity versions of LPS, MPL® adjuvant and RC529, are efficient adjuvants for CD4+ T cells BS Thompson, PM Chilton, JR Ward, JT Evans, TC Mitchell Journal of leukocyte biology 78 (6), 1273-1280, 2005 | 172 | 2005 |
Soluble cytokine receptors: their roles in immunoregulation, disease, and therapy R Fernandez-Botran, PM Chilton, Y Ma Advances in immunology 63, 269-336, 1996 | 129 | 1996 |
TNF-α is critical to facilitate hemopoietic stem cell engraftment and function F Rezzoug, Y Huang, MK Tanner, M Wysoczynski, CL Schanie, ... The Journal of Immunology 180 (1), 49-57, 2008 | 126 | 2008 |
Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model RW Sweeney, J Uzonna, RH Whitlock, PL Habecker, P Chilton, P Scott Research in veterinary science 80 (3), 253-259, 2006 | 118 | 2006 |
Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model JE Uzonna, P Chilton, RH Whitlock, PL Habecker, P Scott, RW Sweeney Vaccine 21 (23), 3101-3109, 2003 | 99 | 2003 |
Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients H Xu, PM Chilton, MK Tanner, Y Huang, CL Schanie, M Dy-Liacco, J Yan, ... Blood 108 (10), 3611-3619, 2006 | 92 | 2006 |
Production of donor T cells is critical for induction of donor-specific tolerance and maintenance of chimerism H Xu, PM Chilton, Y Huang, CL Schanie, ST Ildstad The Journal of Immunology 172 (3), 1463-1471, 2004 | 78 | 2004 |
Production of soluble IL-4 receptors by murine spleen cells is regulated by T cell activation and IL-4. PM Chilton, R Fernandez-Botran Journal of immunology (Baltimore, Md.: 1950) 151 (11), 5907-5917, 1993 | 61 | 1993 |
Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state DH Chung, JE Golden, RS Adcock, CE Schroeder, YK Chu, JB Sotsky, ... Antimicrobial agents and chemotherapy 60 (8), 4552-4562, 2016 | 57 | 2016 |
Flt3-ligand treatment prevents diabetes in NOD mice PM Chilton, F Rezzoug, I Fugier-Vivier, LA Weeter, H Xu, Y Huang, ... Diabetes 53 (8), 1995-2002, 2004 | 57 | 2004 |
Effects of differences in lipid A structure on TLR4 pro-inflammatory signaling and inflammasome activation PM Chilton, CA Embry, TC Mitchell Frontiers in immunology 3, 154, 2012 | 56 | 2012 |
TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion SK Gandhapudi, PM Chilton, TC Mitchell PloS one 8 (2), e56855, 2013 | 53 | 2013 |
Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF JP Kolb, CR Casella, S SenGupta, PM Chilton, TC Mitchell Science signaling 7 (351), ra108-ra108, 2014 | 47 | 2014 |
Adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria PM Chilton, DM Hadel, TT To, TC Mitchell, RP Darveau Infection and immunity 81 (9), 3317-3325, 2013 | 46 | 2013 |
Impaired Bcl3 Up-regulation Leads to Enhanced Lipopolysaccharide-induced Interleukin (IL)-23P19 Gene Expression in IL-10–/–Mice M Mühlbauer, PM Chilton, TC Mitchell, C Jobin Journal of Biological Chemistry 283 (21), 14182-14189, 2008 | 44 | 2008 |
Immunobiology in VCA CL Kaufman, MR Marvin, PM Chilton, JB Hoying, SK Williams, H Tien, ... Transplant International 29 (6), 644-654, 2016 | 42 | 2016 |
CD45 congenic bone marrow transplantation: evidence for T cell–mediated immunity H Xu, BG Exner, PM Chilton, C Schanie, ST Ildstad Stem cells 22 (6), 1039-1048, 2004 | 41 | 2004 |
Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver … R Singhal, H Donde, S Ghare, K Stocke, J Zhang, M Vadhanam, S Reddy, ... Gut microbes 13 (1), 1946367, 2021 | 38 | 2021 |