| Association of CYP2C9*2 With Bosentan‐Induced Liver Injury SM Markova, T De Marco, N Bendjilali, EA Kobashigawa, J Mefford, ... Clinical Pharmacology & Therapeutics 94 (6), 678-686, 2013 | 75 | 2013 |
| A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834 JK Sodhi, S Wong, DS Kirkpatrick, L Liu, SC Khojasteh, CECA Hop, ... Drug Metabolism and Disposition 43 (6), 908-915, 2015 | 59 | 2015 |
| Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties J Gunzner-Toste, G Zhao, P Bauer, T Baumeister, AJ Buckmelter, ... Bioorganic & medicinal chemistry letters 23 (12), 3531-3538, 2013 | 43 | 2013 |
| Successful and unsuccessful prediction of human hepatic clearance for lead optimization JK Sodhi, LZ Benet Journal of medicinal chemistry 64 (7), 3546-3559, 2021 | 40 | 2021 |
| Understanding drug–drug interaction and pharmacogenomic changes in pharmacokinetics for metabolized drugs LZ Benet, CM Bowman, ML Koleske, CL Rinaldi, JK Sodhi Journal of pharmacokinetics and pharmacodynamics 46, 155-163, 2019 | 40 | 2019 |
| Minimizing CYP2C9 inhibition of exposed-pyridine NAMPT (nicotinamide phosphoribosyltransferase) inhibitors M Zak, P Yuen, X Liu, S Patel, D Sampath, J Oeh, BM Liederer, W Wang, ... Journal of Medicinal Chemistry 59 (18), 8345-8368, 2016 | 37 | 2016 |
| Investigating the Theoretical Basis for In Vitro–In Vivo Extrapolation (IVIVE) in Predicting Drug Metabolic Clearance and Proposing Future Experimental Pathways LZ Benet, JK Sodhi The AAPS journal 22 (5), 120, 2020 | 35 | 2020 |
| Pharmacogenomics in the era of next generation sequencing–from byte to bedside LE Russell, Y Zhou, AA Almousa, JK Sodhi, CK Nwabufo, VM Lauschke Drug Metabolism Reviews 53 (2), 253-278, 2021 | 31 | 2021 |
| Are there any experimental perfusion data that preferentially support the dispersion and parallel-tube models over the well-stirred model of organ elimination? JK Sodhi, HJ Wang, LZ Benet Drug Metabolism and Disposition 48 (7), 537-543, 2020 | 30 | 2020 |
| Can In Vitro–In Vivo Extrapolation Be Successful? Recognizing the Incorrect Clearance Assumptions LZ Benet, JK Sodhi Clinical Pharmacology & Therapeutics 111 (5), 1022-1035, 2022 | 25 | 2022 |
| There is only one valid definition of clearance: critical examination of clearance concepts reveals the potential for errors in clinical drug dosing decisions LZ Benet, JK Sodhi, G Makrygiorgos, A Mesbah The AAPS journal 23 (3), 67, 2021 | 25 | 2021 |
| Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data J Yadav, M El Hassani, J Sodhi, VM Lauschke, JH Hartman, LE Russell Drug metabolism reviews 53 (2), 207-233, 2021 | 24 | 2021 |
| How transporters have changed basic pharmacokinetic understanding LZ Benet, CM Bowman, JK Sodhi The AAPS journal 21 (6), 103, 2019 | 23 | 2019 |
| The extended clearance concept following oral and intravenous dosing: theory and critical analyses LZ Benet, CM Bowman, S Liu, JK Sodhi Pharmaceutical research 35, 1-12, 2018 | 21 | 2018 |
| Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications KA Ford, G Ryslik, J Sodhi, J Halladay, D Diaz, D Dambach, M Masuda Drug Metabolism Reviews 47 (3), 291-319, 2015 | 20 | 2015 |
| Intestinal efflux transporters P-gp and BCRP are not clinically relevant in apixaban disposition JK Sodhi, S Liu, LZ Benet Pharmaceutical research 37, 1-13, 2020 | 18 | 2020 |
| Volume of distribution is unaffected by metabolic drug–drug interactions JK Sodhi, CH Huang, LZ Benet Clinical pharmacokinetics 60 (2), 205-222, 2021 | 12 | 2021 |
| 1-Aminobenzotriazole coincubated with (S)-warfarin results in potent inactivation of CYP2C9 JK Sodhi, KA Ford, S Mukadam, S Wong, CECA Hop, SC Khojasteh, ... Drug Metabolism and Disposition 42 (5), 813-817, 2014 | 12 | 2014 |
| The necessity of using changes in absorption time to implicate intestinal transporter involvement in oral drug-drug interactions JK Sodhi, LZ Benet The AAPS journal 22 (5), 111, 2020 | 11 | 2020 |
| The effects of drug metabolizing enzyme inhibitors on hepatic efflux and uptake transporters J Cheong, JS Halladay, E Plise, JK Sodhi, L Salphati Drug metabolism letters 11 (2), 111-118, 2017 | 11 | 2017 |
