Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data M van der Lee, WG Allard, RHAM Vossen, RF Baak-Pablo, R Menafra, ... Science translational medicine 13 (603), eabf3637, 2021 | 58 | 2021 |
Technologies for pharmacogenomics: a review M van der Lee, M Kriek, HJ Guchelaar, JJ Swen Genes 11 (12), 1456, 2020 | 57 | 2020 |
Artificial intelligence in pharmacology research and practice M van der Lee, JJ Swen Clinical and Translational Science 16 (1), 31-36, 2023 | 42 | 2023 |
Repurposing of diagnostic whole exome sequencing data of 1,583 individuals for clinical pharmacogenetics M van der Lee, WG Allard, S Bollen, GWE Santen, CAL Ruivenkamp, ... Clinical Pharmacology & Therapeutics 107 (3), 617-627, 2020 | 33 | 2020 |
Application of long-read sequencing to elucidate complex pharmacogenomic regions: a proof of principle M van der Lee, WJ Rowell, R Menafra, HJ Guchelaar, JJ Swen, SY Anvar The pharmacogenomics journal 22 (1), 75-81, 2022 | 24 | 2022 |
Why we need to take a closer look at genetic contributions to CYP3A activity Q Zhai, M van der Lee, T van Gelder, JJ Swen Frontiers in Pharmacology 13, 912618, 2022 | 21 | 2022 |
Substrate specificity of CYP2D6 genetic variants M van der Lee, HJ Guchelaar, JJ Swen Pharmacogenomics 22 (16), 1081-1089, 2021 | 17 | 2021 |
A unifying model to predict variable drug response for personalised medicine M van der Lee, WG Allard, RHAM Vossen, RF Baak-Pablo, R Menafra, ... Biorxiv, 2020.03. 02.967554, 2020 | 15 | 2020 |
Development of an extensive workflow for comprehensive clinical pharmacogenomic profiling: lessons from a pilot study on 100 whole exome sequencing data A Tafazoli, M van der Lee, JJ Swen, A Zeller, N Wawrusiewicz-Kurylonek, ... The Pharmacogenomics Journal 22 (5), 276-283, 2022 | 9 | 2022 |
Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network D Feick, S Rüdesheim, FZ Marok, D Selzer, HLH Loer, D Teutonico, ... CPT: Pharmacometrics & Systems Pharmacology 12 (8), 1143-1156, 2023 | 7 | 2023 |
Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions HLH Loer, D Feick, S Rüdesheim, D Selzer, M Schwab, D Teutonico, ... CPT: Pharmacometrics & Systems Pharmacology 12 (5), 724-738, 2023 | 5 | 2023 |
From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C19 LJ Graansma, Q Zhai, L Busscher, R Menafra, RR van den Berg, SL Kloet, ... Frontiers in Pharmacology 14, 1076574, 2023 | 4 | 2023 |
Atopic dermatitis characteristics and medication‐use patterns in school‐age children with AD and asthma symptoms M van der Lee, A Arabkhazaeli, FC van Erp, JA Raaijmakers, ... Clinical and experimental dermatology 42 (5), 503-508, 2017 | 3 | 2017 |
Study protocol of the HD-MED study aiming to personalize drug treatment in Huntington’s disease: a longitudinal, observational study to assess medication use and efficacy in … S Feleus, M van der Lee, JJ Swen, RAC Roos, ST de Bot Therapeutic Advances in Rare Disease 4, 26330040231204643, 2023 | 2 | 2023 |
Pharmacogenetic Panel Testing: A Review of Current Practice and Potential for Clinical Implementation R Mosch, M van der Lee, HJ Guchelaar, JJ Swen Annual Review of Pharmacology and Toxicology 65, 2025 | 1 | 2025 |
Addendum To: Study protocol of the HD-MED study aiming to personalize drug treatment in Huntington’s disease: a longitudinal, observational study to assess medication use and … S Feleus, M van der Lee, JJ Swen, RAC Roos, ST de Bot Therapeutic Advances in Rare Disease 5, 26330040241270369, 2024 | 1 | 2024 |
Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD JE Knikman, Q Zhai, CATC Lunenburg, LM Henricks, S Böhringer, ... Genome medicine 16 (1), 101, 2024 | 1 | 2024 |
Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity: A case series EC Bernsen, LM Hanff, LM Haveman, BBJ Tops, M van der Lee, JJ Swen, ... Journal of Oncology Pharmacy Practice 29 (5), 1237-1245, 2023 | 1 | 2023 |
Patterns of topical corticosteroids prescriptions in children with asthma A Arabkhazaeli, SJH Vijverberg, M van der Lee, CK van der Ent, ... Pediatric dermatology 35 (3), 378-383, 2018 | 1 | 2018 |
The effect of genetic variants in the transcription factor TSPYL family on the CYP3A4 mediated cyclosporine metabolism in kidney transplant patients Q Zhai, DJAR Moes, T van Gelder, M van Der Lee, JS Sanders, ... Clinical and translational science 17 (2), e13729, 2024 | | 2024 |