Variolins and related alkaloids SR Walker, EJ Carter, BC Huff, JC Morris Chemical reviews 109 (7), 3080-3098, 2009 | 288 | 2009 |
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex A Echalier, K Bettayeb, Y Ferandin, O Lozach, M Clément, A Valette, ... Journal of medicinal chemistry 51 (4), 737-751, 2008 | 176 | 2008 |
Meriolins, a new class of cell death–inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases K Bettayeb, OM Tirado, S Marionneau-Lambot, Y Ferandin, O Lozach, ... Cancer Research 67 (17), 8325-8334, 2007 | 176 | 2007 |
The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity A Collison, L Hatchwell, N Verrills, PAB Wark, AP De Siqueira, M Tooze, ... Nature medicine 19 (2), 232-237, 2013 | 155 | 2013 |
Brief screening tests versus clinical staging in senile dementia of the Alzheimer type PB Davis, JC Morris, E Grant Journal of the American Geriatrics Society 38 (2), 129-135, 1990 | 134 | 1990 |
Dibenzotetraphenylperiflanthene: synthesis, photophysical properties, and electrogenerated chemiluminescence JD Debad, JC Morris, V Lynch, P Magnus, AJ Bard Journal of the American Chemical Society 118 (10), 2374-2379, 1996 | 128 | 1996 |
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism N Turner, XY Lim, HD Toop, B Osborne, AE Brandon, EN Taylor, ... Nature communications 9 (1), 3165, 2018 | 123 | 2018 |
MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity JJ Li, HL Tay, S Maltby, Y Xiang, F Eyers, L Hatchwell, H Zhou, HD Toop, ... Journal of allergy and clinical immunology 136 (2), 462-473, 2015 | 107 | 2015 |
Pharmacology of modulators of alternative splicing DO Bates, JC Morris, S Oltean, LF Donaldson Pharmacological reviews 69 (1), 63-79, 2017 | 102 | 2017 |
Development of potent, selective SRPK1 inhibitors as potential topical therapeutics for neovascular eye disease J Batson, HD Toop, C Redondo, R Babaei-Jadidi, A Chaikuad, ... ACS chemical biology 12 (3), 825-832, 2017 | 100 | 2017 |
Anodic Coupling of Diphenylbenzo[k]fluoranthene: Mechanistic and Kinetic Studies Utilizing Cyclic Voltammetry and Electrogenerated Chemiluminescence JD Debad, JC Morris, P Magnus, AJ Bard The Journal of Organic Chemistry 62 (3), 530-537, 1997 | 76 | 1997 |
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 K Tzelepis, E De Braekeleer, D Aspris, I Barbieri, MS Vijayabaskar, ... Nature communications 9 (1), 5378, 2018 | 68 | 2018 |
Total synthesis of variolin B RJ Anderson, JC Morris Tetrahedron Letters 42 (49), 8697-8699, 2001 | 61 | 2001 |
Concise total syntheses of variolin B and deoxyvariolin B RJ Anderson, JB Hill, JC Morris The Journal of Organic Chemistry 70 (16), 6204-6212, 2005 | 58 | 2005 |
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies SJ Roberts, JC Morris, RCJ Dobson, JA Gerrard Bioorganic & medicinal chemistry letters 13 (2), 265-267, 2003 | 56 | 2003 |
Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change SCK Sukuru, T Crepin, Y Milev, LC Marsh, JB Hill, RJ Anderson, ... Journal of computer-aided molecular design 20, 159-178, 2006 | 55 | 2006 |
Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors AM Smith, MD Dun, EM Lee, C Harrison, R Kahl, H Flanagan, N Panicker, ... Oncotarget 7 (30), 47465, 2016 | 50 | 2016 |
Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells MM Rahman, NN Rumzhum, PM Hansbro, JC Morris, AR Clark, ... Cellular signalling 28 (4), 325-334, 2016 | 48 | 2016 |
Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Regulates Hallmark Features of Airways Remodeling in Allergic Airways Disease A Collison, J Li, A Pereira de Siqueira, J Zhang, HD Toop, JC Morris, ... American journal of respiratory cell and molecular biology 51 (1), 86-93, 2014 | 48 | 2014 |
Dual side-reactions limit the utility of a key polymer therapeutic precursor SRA Devenish, JB Hill, JW Blunt, JC Morris, MHG Munro Tetrahedron letters 47 (17), 2875-2878, 2006 | 45 | 2006 |