Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection I Gutierrez-Aranda, V Ramos-Mejia, C Bueno, M Munoz-Lopez, PJ Real, ... Stem cells 28 (9), 1568-1570, 2010 | 414 | 2010 |
Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ... Cell stem cell 21 (3), 319-331. e8, 2017 | 290 | 2017 |
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells NG Coufal, JL Garcia-Perez, GE Peng, MCN Marchetto, AR Muotri, Y Mu, ... Proceedings of the National Academy of Sciences 108 (51), 20382-20387, 2011 | 250 | 2011 |
Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility S Wissing, M Munoz-Lopez, A Macia, Z Yang, M Montano, W Collins, ... Human molecular genetics 21 (1), 208-218, 2012 | 167 | 2012 |
Engineered LINE-1 retrotransposition in nondividing human neurons A Macia, TJ Widmann, SR Heras, V Ayllon, L Sanchez, ... Genome research 27 (3), 335-348, 2017 | 164 | 2017 |
Epigenetic control of retrotransposon expression in human embryonic stem cells A Macia, M Munoz-Lopez, JL Cortes, RK Hastings, S Morell, ... Molecular and cellular biology, 2011 | 159 | 2011 |
Transposable elements, inflammation, and neurological disease A Saleh, A Macia, AR Muotri Frontiers in neurology 10, 894, 2019 | 134 | 2019 |
LINE-1 evasion of epigenetic repression in humans FJ Sanchez-Luque, MJHC Kempen, P Gerdes, DB Vargas-Landin, ... Molecular cell 75 (3), 590-604. e12, 2019 | 130 | 2019 |
Genome-wide de novo L1 retrotransposition connects endonuclease activity with replication DA Flasch, Á Macia, L Sánchez, M Ljungman, SR Heras, JL García-Pérez, ... Cell 177 (4), 837-851. e28, 2019 | 119 | 2019 |
Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ... Scientific reports 8 (1), 1218, 2018 | 79 | 2018 |
LINE‐1 retrotransposons in healthy and diseased human brain NA Suarez, A Macia, AR Muotri Developmental neurobiology 78 (5), 434-455, 2018 | 77 | 2018 |
Sofosbuvir protects human brain organoids against SARS-CoV-2 P Mesci, A Macia, A Saleh, L Martin-Sancho, X Yin, C Snethlage, ... BioRxiv, 2020.05. 30.125856, 2020 | 64 | 2020 |
Modeling neuro-immune interactions during Zika virus infection P Mesci, A Macia, CN LaRock, L Tejwani, IR Fernandes, NA Suarez, ... Human Molecular Genetics 27 (1), 41-52, 2018 | 58 | 2018 |
Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor A Morales-Hernández, FJ González-Rico, AC Román, E Rico-Leo, ... Nucleic acids research 44 (10), 4665-4683, 2016 | 52 | 2016 |
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir P Mesci, JS de Souza, L Martin-Sancho, A Macia, A Saleh, X Yin, ... PLoS biology 20 (11), e3001845, 2022 | 32 | 2022 |
Retrotransposons in pluripotent cells: Impact and new roles in cellular plasticity A Macia, E Blanco-Jimenez, JL García-Pérez Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (4), 417-426, 2015 | 29 | 2015 |
An epi [c] genetic battle: LINE-1 retrotransposons and intragenomic conflict in humans M Muñoz-Lopez, A Macia, M Garcia-Cañadas, RM Badge, ... Mobile genetic elements 1 (2), 122-127, 2011 | 23 | 2011 |
Analysis of LINE-1 expression in human pluripotent cells M Muñoz-Lopez, M Garcia-Cañadas, A Macia, S Morell, JL Garcia-Perez Human Embryonic Stem Cells Handbook, 113-125, 2012 | 18 | 2012 |
LINE-1 retrotransposition impacts the genome of human pre-implantation embryos and extraembryonic tissues M Muñoz-Lopez, R Vilar, C Philippe, R Rahbari, SR Richardson, ... BioRxiv, 522623, 2019 | 8 | 2019 |
Activity of retrotransposons in stem cells and differentiated cells A Macia, L Tejwani, P Mesci, A Muotri, JL Garcia-Perez Human Retrotransposons in Health and Disease, 127-156, 2017 | 5 | 2017 |