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| XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast EL Van Dijk, CL Chen, Y d’Aubenton-Carafa, S Gourvennec, M Kwapisz, ... Nature 475 (7354), 114-117, 2011 | 420 | 2011 |
| Replication landscape of the human genome N Petryk, M Kahli, Y d'Aubenton-Carafa, Y Jaszczyszyn, Y Shen, M Silvain, ... Nature communications 7 (1), 10208, 2016 | 317 | 2016 |
| Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes CL Chen, A Rappailles, L Duquenne, M Huvet, G Guilbaud, L Farinelli, ... Genome research 20 (4), 447-457, 2010 | 251 | 2010 |
| Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome G Guilbaud, A Rappailles, A Baker, CL Chen, A Arneodo, A Goldar, ... PLoS computational biology 7 (12), e1002322, 2011 | 155 | 2011 |
| Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites A Promonet, I Padioleau, Y Liu, L Sanz, A Biernacka, AL Schmitz, ... Nature communications 11 (1), 3940, 2020 | 138 | 2020 |
| Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs ZP Huang, H Zhou, HL He, CL Chen, D Liang, LH Qu Rna 11 (8), 1303-1316, 2005 | 98 | 2005 |
| The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa CL Chen, D Liang, H Zhou, M Zhuo, YQ Chen, LH Qu Nucleic acids research 31 (10), 2601-2613, 2003 | 93 | 2003 |
| Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide O Brison, S El-Hilali, D Azar, S Koundrioukoff, M Schmidt, V Nähse, ... Nature communications 10 (1), 5693, 2019 | 90 | 2019 |
| Tight protein–DNA interactions favor gene silencing M Dubarry, I Loïodice, CL Chen, C Thermes, A Taddei Genes & Development 25 (13), 1365-1370, 2011 | 89 | 2011 |
| Replication-associated mutational asymmetry in the human genome CL Chen, L Duquenne, B Audit, G Guilbaud, A Rappailles, A Baker, ... Molecular biology and evolution 28 (8), 2327-2337, 2011 | 83 | 2011 |
| Replication fork polarity gradients revealed by megabase-sized U-shaped replication timing domains in human cell lines A Baker, B Audit, CL Chen, B Moindrot, A Leleu, G Guilbaud, A Rappailles, ... PLoS computational biology 8 (4), e1002443, 2012 | 81 | 2012 |
| Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication W Wang, KN Klein, K Proesmans, H Yang, C Marchal, X Zhu, T Borrman, ... Molecular cell 81 (14), 2975-2988. e6, 2021 | 73 | 2021 |
| DNA polymerase α interacts with H3-H4 and facilitates the transfer of parental histones to lagging strands Z Li, X Hua, A Serra-Cardona, X Xu, S Gan, H Zhou, WS Yang, C Chen, ... Science advances 6 (35), eabb5820, 2020 | 69 | 2020 |
| Cohesin-mediated loop anchors confine the locations of human replication origins DJ Emerson, PA Zhao, AL Cook, RJ Barnett, KN Klein, D Saulebekova, ... Nature 606 (7915), 812-819, 2022 | 58 | 2022 |
| Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm B Audit, A Baker, CL Chen, A Rappailles, G Guilbaud, H Julienne, ... Nature protocols 8 (1), 98-110, 2013 | 58 | 2013 |
| A novel gene organization: intronic snoRNA gene clusters from Oryza sativa D Liang, H Zhou, P Zhang, YQ Chen, X Chen, CL Chen, LH Qu Nucleic acids research 30 (14), 3262-3272, 2002 | 53 | 2002 |
| Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer MJ Shi, XY Meng, J Fontugne, CL Chen, F Radvanyi, I Bernard-Pierrot Genome medicine 12, 1-20, 2020 | 50 | 2020 |
| APOBEC-mediated mutagenesis as a likely cause of FGFR3 S249C mutation over-representation in bladder cancer MJ Shi, XY Meng, P Lamy, AR Banday, J Yang, A Moreno-Vega, CL Chen, ... European urology 76 (1), 9-13, 2019 | 46 | 2019 |
| From simple bacterial and archaeal replicons to replication N/U-domains O Hyrien, A Rappailles, G Guilbaud, A Baker, CL Chen, A Goldar, ... Journal of molecular biology 425 (23), 4673-4689, 2013 | 43 | 2013 |
Olivier Hyrien在 biologie.ens.fr 的电子邮件经过验证
