NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts X Fan, L Khaki, TS Zhu, ME Soules, CE Talsma, N Gul, C Koh, J Zhang, ... Stem cells 28 (1), 5-16, 2010 | 790 | 2010 |
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology I Singec, R Knoth, RP Meyer, J Maciaczyk, B Volk, G Nikkhah, M Frotscher, ... Nature methods 3 (10), 801-806, 2006 | 483 | 2006 |
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition UD Kahlert, D Maciaczyk, S Doostkam, BA Orr, B Simons, T Bogiel, ... Cancer letters 325 (1), 42-53, 2012 | 254 | 2012 |
Epithelial-to-mesenchymal (-like) transition as a relevant molecular event in malignant gliomas UD Kahlert, G Nikkhah, J Maciaczyk Cancer letters 331 (2), 131-138, 2013 | 239 | 2013 |
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model EH Raabe, KS Lim, JM Kim, A Meeker, X Mao, G Nikkhah, J Maciaczyk, ... Clinical Cancer Research 17 (11), 3590-3599, 2011 | 209 | 2011 |
Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine–DNA Methyltransferase Nonmethylated Glioblastoma: The … U Herrlinger, N Schäfer, JP Steinbach, A Weyerbrock, P Hau, ... Journal of Clinical Oncology 34 (14), 1611-1619, 2016 | 197 | 2016 |
DNER, an Epigenetically Modulated Gene, Regulates Glioblastoma-Derived Neurosphere Cell Differentiation and Tumor Propagation P Sun, S Xia, B Lal, CG Eberhart, A Quinones-Hinojosa, J Maciaczyk, ... Stem cells 27 (7), 1473-1486, 2009 | 107 | 2009 |
Histological findings on fetal striatal grafts in a Huntington's disease patient early after transplantation P Capetian, R Knoth, J Maciaczyk, G Pantazis, M Ditter, L Bokla, ... Neuroscience 160 (3), 661-675, 2009 | 96 | 2009 |
ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres UD Kahlert, AK Suwala, EH Raabe, FA Siebzehnrubl, MJ Suarez, BA Orr, ... Brain pathology 25 (6), 724-732, 2015 | 79 | 2015 |
Pharmacologic Wnt inhibition reduces proliferation, survival, and clonogenicity of glioblastoma cells UD Kahlert, AK Suwala, K Koch, M Natsumeda, BA Orr, M Hayashi, ... Journal of neuropathology and experimental neurology 74 (9), 889-900, 2015 | 79 | 2015 |
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program X Mao, M Hütt-Cabezas, BA Orr, M Weingart, I Taylor, AKD Rajan, Y Odia, ... Oncotarget 4 (7), 1050, 2013 | 78 | 2013 |
Targeting cancer stem‐like cells in glioblastoma and colorectal cancer through metabolic pathways UD Kahlert, SM Mooney, M Natsumeda, HJ Steiger, J Maciaczyk International Journal of Cancer 140 (1), 10-22, 2017 | 69 | 2017 |
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity K Koch, R Hartmann, J Tsiampali, C Uhlmann, AC Nickel, X He, MA Kamp, ... Cell death discovery 6 (1), 20, 2020 | 68 | 2020 |
Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro AK Suwala, K Koch, DH Rios, P Aretz, C Uhlmann, I Ogorek, J Felsberg, ... Oncotarget 9 (32), 22703, 2018 | 68 | 2018 |
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets AR Hanaford, TC Archer, A Price, UD Kahlert, J Maciaczyk, G Nikkhah, ... Clinical Cancer Research 22 (15), 3903-3914, 2016 | 65 | 2016 |
Primary cerebral intraventricular hydatid cyst: a case report and review of the literature A Guzel, M Tatli, J Maciaczyk, N Altinors Journal of child neurology 23 (5), 585-588, 2008 | 64 | 2008 |
Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of … J Maciaczyk, I Singec, D Maciaczyk, G Nikkhah Experimental neurology 213 (2), 354-362, 2008 | 61 | 2008 |
Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson's disease A Rath, A Klein, A Papazoglou, J Pruszak, J Garcia, M Krause, ... Cell Transplantation 22 (7), 1281-1293, 2013 | 54 | 2013 |
Clipping the wings of glioblastoma: modulation of WNT as a novel therapeutic strategy AK Suwala, A Hanaford, UD Kahlert, J Maciaczyk Journal of Neuropathology & Experimental Neurology 75 (5), 388-396, 2016 | 51 | 2016 |
Limited Ca2+ and PKA-pathway dependent neurogenic differentiation of human adult mesenchymal stem cells as compared to fetal neuronal stem cells G Lepski, CE Jannes, J Maciaczyk, A Papazoglou, AT Mehlhorn, S Kaiser, ... Experimental cell research 316 (2), 216-231, 2010 | 51 | 2010 |