Fidelity at the molecular level: lessons from protein synthesis HS Zaher, R Green Cell 136 (4), 746-762, 2009 | 438 | 2009 |
Ribosome collision is critical for quality control during no-go decay CL Simms, LL Yan, HS Zaher Molecular cell 68 (2), 361-373. e5, 2017 | 276 | 2017 |
Quality control by the ribosome following peptide bond formation HS Zaher, R Green Nature 457 (7226), 161-166, 2009 | 260 | 2009 |
Selection of an improved RNA polymerase ribozyme with superior extension and fidelity HS Zaher, PJ Unrau Rna 13 (7), 1017-1026, 2007 | 235 | 2007 |
An active role for the ribosome in determining the fate of oxidized mRNA CL Simms, BH Hudson, JW Mosior, AS Rangwala, HS Zaher Cell reports 9 (4), 1256-1264, 2014 | 206 | 2014 |
How do cells cope with RNA damage and its consequences? LL Yan, HS Zaher Journal of Biological Chemistry 294 (41), 15158-15171, 2019 | 139 | 2019 |
A short translational ramp determines the efficiency of protein synthesis M Verma, J Choi, KA Cottrell, Z Lavagnino, EN Thomas, ... Nature communications 10 (1), 5774, 2019 | 137 | 2019 |
Ribosome‐based quality control of mRNA and nascent peptides CL Simms, EN Thomas, HS Zaher Wiley Interdisciplinary Reviews: RNA 8 (1), e1366, 2017 | 124 | 2017 |
Hyperaccurate and error-prone ribosomes exploit distinct mechanisms during tRNA selection HS Zaher, R Green Molecular cell 39 (1), 110-120, 2010 | 111 | 2010 |
Quality control of chemically damaged RNA CL Simms, HS Zaher Cellular and Molecular Life Sciences 73, 3639-3653, 2016 | 101 | 2016 |
Ribosome quality control antagonizes the activation of the integrated stress response on colliding ribosomes LL Yan, HS Zaher Molecular cell 81 (3), 614-628. e4, 2021 | 98 | 2021 |
Oxidation and alkylation stresses activate ribosome-quality control LL Yan, CL Simms, F McLoughlin, RD Vierstra, HS Zaher Nature communications 10 (1), 5611, 2019 | 77 | 2019 |
The 2′‐OH group of the peptidyl‐tRNA stabilizes an active conformation of the ribosomal PTC HS Zaher, JJ Shaw, SA Strobel, R Green The EMBO Journal 30 (12), 2445-2453, 2011 | 75 | 2011 |
A primary role for release factor 3 in quality control during translation elongation in Escherichia coli HS Zaher, R Green Cell 147 (2), 396-408, 2011 | 66 | 2011 |
Ribosome collisions result in+ 1 frameshifting in the absence of no-go decay CL Simms, LL Yan, JK Qiu, HS Zaher Cell reports 28 (7), 1679-1689. e4, 2019 | 55 | 2019 |
Uniformity of peptide release is maintained by methylation of release factors WE Pierson, ED Hoffer, HE Keedy, CL Simms, CM Dunham, HS Zaher Cell reports 17 (1), 11-18, 2016 | 53 | 2016 |
Canary in a coal mine: collided ribosomes as sensors of cellular conditions KQ Kim, HS Zaher Trends in biochemical sciences 47 (1), 82-97, 2022 | 45 | 2022 |
T7 RNA polymerase mediates fast promoter-independent extension of unstable nucleic acid complexes HS Zaher, PJ Unrau Biochemistry 43 (24), 7873-7880, 2004 | 45 | 2004 |
O6-Methylguanosine leads to position-dependent effects on ribosome speed and fidelity BH Hudson, HS Zaher Rna 21 (9), 1648-1659, 2015 | 43 | 2015 |
Distinct roles for release factor 1 and release factor 2 in translational quality control AD Petropoulos, ME McDonald, R Green, HS Zaher Journal of Biological Chemistry 289 (25), 17589-17596, 2014 | 36 | 2014 |