Mycobacterial aminoglycoside acetyltransferases: a little of drug resistance, and a lot of other roles F Sanz-García, E Anoz-Carbonell, E Pérez-Herrán, C Martín, A Lucía, ... Frontiers in Microbiology 10, 46, 2019 | 48 | 2019 |
The catalytic cycle of the antioxidant and cancer-associated human NQO1 enzyme: Hydride transfer, conformational dynamics and functional cooperativity E Anoz-Carbonell, DJ Timson, AL Pey, M Medina Antioxidants 9 (9), 772, 2020 | 31 | 2020 |
A Natural Chimeric Pseudomonas Bacteriocin with Novel Pore-Forming Activity Parasitizes the Ferrichrome Transporter MGK Ghequire, L Kemland, E Anoz-Carbonell, SK Buchanan, R De Mot MBio 8 (1), 10.1128/mbio. 01961-16, 2017 | 30 | 2017 |
Discovery of antimicrobial compounds targeting bacterial type FAD synthetases M Sebastián, E Anoz-Carbonell, B Gracia, P Cossio, JA Aínsa, I Lans, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 241-254, 2018 | 29 | 2018 |
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD (P) H: quinone oxidoreductase 1 and their … JL Pacheco-Garcia, E Anoz-Carbonell, P Vankova, A Kannan, ... Redox Biology 46, 102112, 2021 | 27 | 2021 |
In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target I Lans, E Anoz-Carbonell, K Palacio-Rodríguez, JA Aínsa, M Medina, ... PLoS computational biology 16 (8), e1007898, 2020 | 19 | 2020 |
Allosteric communication in the multifunctional and redox NQO1 protein studied by cavity-making mutations JL Pacheco-Garcia, DS Loginov, E Anoz-Carbonell, P Vankova, ... Antioxidants 11 (6), 1110, 2022 | 17 | 2022 |
Targeting HIF-1α function in cancer through the chaperone action of NQO1: implications of genetic diversity of NQO1 E Salido, DJ Timson, I Betancor-Fernández, R Palomino-Morales, ... Journal of personalized medicine 12 (5), 747, 2022 | 17 | 2022 |
Human riboflavin kinase: Species‐specific traits in the biosynthesis of the FMN cofactor E Anoz‐Carbonell, M Rivero, V Polo, A Velázquez‐Campoy, M Medina The FASEB Journal 34 (8), 10871-10886, 2020 | 15 | 2020 |
Mutation of aspartate 238 in FAD synthase isoform 6 increases the specific activity by weakening the FAD binding P Leone, M Galluccio, S Quarta, E Anoz-Carbonell, M Medina, C Indiveri, ... International journal of molecular sciences 20 (24), 6203, 2019 | 15 | 2019 |
Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis A Moreno, V Taleb, M Sebastián, E Anoz‐Carbonell, M Martínez‐Júlvez, ... IUBMB life 74 (7), 655-671, 2022 | 12 | 2022 |
Towards the competent conformation for catalysis in the ferredoxin-NADP+ reductase from the Brucella ovis pathogen D Pérez-Amigot, V Taleb, S Boneta, E Anoz-Carbonell, M Sebastián, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1860 (10), 148058, 2019 | 9 | 2019 |
Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies S Salillas, JJ Galano-Frutos, A Mahía, R Maity, M Conde-Giménez, ... International Journal of Molecular Sciences 22 (18), 10137, 2021 | 6 | 2021 |
A novel natural siderophore antibiotic conjugate reveals a chemical approach to macromolecule coupling T Caradec, E Anoz-Carbonell, R Petrov, M Billamboz, K Antraygues, ... ACS Central Science 9 (11), 2138-2149, 2023 | 5 | 2023 |
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease‐associated NQO1 enzyme JL Pacheco‐García, E Anoz‐Carbonell, DS Loginov, D Kavan, E Salido, ... The FEBS Journal 290 (7), 1855-1873, 2023 | 5 | 2023 |
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations JL Pacheco-Garcia, E Anoz-Carbonell, DS Loginov, P Vankova, E Salido, ... Archives of Biochemistry and Biophysics 729, 109392, 2022 | 5 | 2022 |
Molecular and dynamic mechanisms of prokaryotic and eukaryotic flavoenzymes: insights into their implication in human metabolism and health EA Carbonell Universidad de Zaragoza (Espagne), 2021 | | 2021 |
Resisting antimicrobial resistance: Flavodoxin inhibitors to combat Helicobacter pylori infection S Salillas, M Alías, V Michel, A Mahía Moros, M Conde-Giménez, ... | | 2020 |
The folded FAD conformation in the ferredoxin-NADP (+) reductase from the Brucella ovis pathogen governs the NADPH dependent reductive-half reaction D Perez-Amigot, V Taleb, S Boneta, E Anoz-Carbonell, M Sebastian, ... EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 48, S138-S138, 2019 | | 2019 |
The FAD synthetase in the spotlight: new antimicrobials targeting the biosynthesis of flavin cofactors E Anoz-Carbonell, M Sebastian, AL Quintana, S Salillas, JA Ainsa, ... FEBS JOURNAL 284, 308-308, 2017 | | 2017 |