| Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress KJ Cowan, KB Storey Journal of Experimental Biology 206 (7), 1107-1115, 2003 | 727 | 2003 |
| Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor R Deng, D Bumbaca, CV Pastuskovas, CA Boswell, D West, KJ Cowan, ... MAbs 8 (3), 593-603, 2016 | 186 | 2016 |
| Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration Y Zheng, DB Tesar, L Benincosa, H Birnböck, CA Boswell, D Bumbaca, ... MAbs 4 (2), 243-255, 2012 | 132 | 2012 |
| Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys MK Leabman, YG Meng, RF Kelley, LE DeForge, KJ Cowan, S Iyer MAbs 5 (6), 896-903, 2013 | 124 | 2013 |
| Identification of Shc as the primary protein binding to the tyrosine-phosphorylated β3 subunit of αIIbβ3 during outside-in integrin platelet signaling KJ Cowan, DA Law, DR Phillips Journal of Biological Chemistry 275 (46), 36423-36429, 2000 | 122 | 2000 |
| Polyglutamine protein aggregation and toxicity are linked to the cellular stress response KJ Cowan, MI Diamond, WJ Welch Human molecular genetics 12 (12), 1377-1391, 2003 | 98 | 2003 |
| Construction and rapid testing of synthetic and modified toxin gene sequences CryIA (b&c) by expression in maize endosperm culture R Sardana, S Dukiandjiev, M Giband, X Cheng, K Cowan, C Sauder, ... Plant Cell Reports 15, 677-681, 1996 | 95 | 1996 |
| Recommendations for use and fit-for-purpose validation of biomarker multiplex ligand binding assays in drug development D Jani, J Allinson, F Berisha, KJ Cowan, V Devanarayan, C Gleason, ... The AAPS journal 18, 1-14, 2016 | 64 | 2016 |
| Freeze-thaw effects on metabolic enzymes in wood frog organs KJ Cowan, KB Storey Cryobiology 43 (1), 32-45, 2001 | 58 | 2001 |
| Metabolic reorganization and signal transduction during estivation in the spadefoot toad KJ Cowan, JA MacDonald, JM Storey, KB Storey Experimental Biology Online 5, 1-25, 2000 | 56 | 2000 |
| 2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV):(Part 3–LBA, biomarkers and immunogenicity) S Richards, L Amaravadi, R Pillutla, H Birnboeck, A Torri, KJ Cowan, ... Bioanalysis 8 (23), 2475-2496, 2016 | 52 | 2016 |
| Effects of RG7652, a monoclonal antibody against PCSK9, on LDL-C, LDL-C subfractions, and inflammatory biomarkers in patients at high risk of or with established coronary heart … A Baruch, S Mosesova, JD Davis, N Budha, A Vilimovskij, R Kahn, K Peng, ... The American journal of cardiology 119 (10), 1576-1583, 2017 | 51 | 2017 |
| The assay design used for measurement of therapeutic antibody concentrations can affect pharmacokinetic parameters: case studies SK Fischer, J Yang, B Anand, K Cowan, R Hendricks, J Li, G Nakamura, ... MAbs 4 (5), 623-631, 2012 | 46 | 2012 |
| Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques S Li, P Kievit, AK Robertson, G Kolumam, X Li, K von Wachenfeldt, ... Molecular metabolism 2 (3), 256-269, 2013 | 42 | 2013 |
| Reversible phosphorylation control of skeletal muscle pyruvate kinase and phosphofructokinase during estivation in the spadefoot toad, Scaphiopus couchii KJ Cowan, KB Storey Molecular and cellular biochemistry 195, 173-181, 1999 | 42 | 1999 |
| Urea and KCl have differential effects on enzyme activities in liver and muscle of estivating versus nonestivating species KJ Cowan, KB Storey Biochemistry and cell biology 80 (6), 745-755, 2002 | 27 | 2002 |
| HGF as a circulating biomarker of onartuzumab treatment in patients with advanced solid tumors E Penuel, C Li, V Parab, L Burton, KJ Cowan, M Merchant, RL Yauch, ... Molecular cancer therapeutics 12 (6), 1122-1130, 2013 | 25 | 2013 |
| Protein kinase and phosphatase responses to anoxia in crayfish, Orconectes virilis: purification and characterization of cAMP-dependent protein kinase KJ Cowan, KB Storey Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2001 | 25 | 2001 |
| Impact of SPR biosensor assay configuration on antibody: Neonatal Fc receptor binding data X Wang, P McKay, LT Yee, G Dutina, PE Hass, I Nijem, D Allison, ... MAbs 9 (2), 319-332, 2017 | 22 | 2017 |
| Recommendations for selection and characterization of protein biomarker assay calibrator material KJ Cowan, L Amaravadi, MJ Cameron, D Fink, D Jani, M Kamat, L King, ... The AAPS Journal 19, 1550-1563, 2017 | 21 | 2017 |
Kenneth B. StoreyCarleton University在 carleton.ca 的电子邮件经过验证
