Rab27a and Rab27b control different steps of the exosome secretion pathway M Ostrowski, NB Carmo, S Krumeich, I Fanget, G Raposo, A Savina, ... Nature cell biology 12 (1), 19-30, 2010 | 2634 | 2010 |
Protein Prenyltransferases (∗) PJ Casey, MC Seabra Journal of Biological Chemistry 271 (10), 5289-5292, 1996 | 1078 | 1996 |
Inhibition of purified p21ras farnesyl: protein transferase by Cys-AAX tetrapeptides Y Reiss, JL Goldstein, MC Seabra, PJ Casey, MS Brown Cell 62 (1), 81-88, 1990 | 1036 | 1990 |
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells A Savina, C Jancic, S Hugues, P Guermonprez, P Vargas, IC Moura, ... Cell 126 (1), 205-218, 2006 | 997 | 2006 |
Evolution of the Rab family of small GTP-binding proteins JB Pereira-Leal, MC Seabra Journal of molecular biology 313 (4), 889-901, 2001 | 976 | 2001 |
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial RE MacLaren, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... The Lancet 383 (9923), 1129-1137, 2014 | 885 | 2014 |
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin M Alexander, R Hu, MC Runtsch, DA Kagele, TL Mosbruger, ... Nature communications 6 (1), 7321, 2015 | 742 | 2015 |
Rab27a supports exosome-dependent and-independent mechanisms that modify the tumor microenvironment and can promote tumor progression A Bobrie, S Krumeich, F Reyal, C Recchi, LF Moita, MC Seabra, ... Cancer research 72 (19), 4920-4930, 2012 | 670 | 2012 |
MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells IS Okoye, SM Coomes, VS Pelly, S Czieso, V Papayannopoulos, ... Immunity 41 (1), 89-103, 2014 | 605 | 2014 |
The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily JB Pereira-Leal, MC Seabra Journal of molecular biology 301 (4), 1077-1087, 2000 | 580 | 2000 |
Rab GTPases, intracellular traffic and disease MC Seabra, EH Mules, AN Hume Trends in molecular medicine 8 (1), 23-30, 2002 | 575 | 2002 |
The melanosome: membrane dynamics in black and white MS Marks, MC Seabra Nature reviews Molecular cell biology 2 (10), 738-748, 2001 | 539 | 2001 |
Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria B Önfelt, S Nedvetzki, RKP Benninger, MA Purbhoo, S Sowinski, ... The Journal of Immunology 177 (12), 8476-8483, 2006 | 515 | 2006 |
Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit MC Seabra, Y Reiss, PJ Casey, MS Brown, JL Goldstein Cell 65 (3), 429-434, 1991 | 481 | 1991 |
Rab27a is required for regulated secretion in cytotoxic T lymphocytes JC Stinchcombe, DC Barral, EH Mules, S Booth, AN Hume, LM Machesky, ... The Journal of cell biology 152 (4), 825-834, 2001 | 471 | 2001 |
cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein DA Andres, MC Seabra, MS Brown, SA Armstrong, TE Smeland, ... Cell 73 (6), 1091-1099, 1993 | 428 | 1993 |
Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys. MC Seabra, JL Goldstein, TC Südhof, MS Brown Journal of Biological Chemistry 267 (20), 14497-14503, 1992 | 419 | 1992 |
GTPase activity of Rab5 acts as a timer for endocytic membrane fusion V Rybin, O Ullrich, M Rubino, K Alexandrov, I Simon, MC Seabra, ... Nature 383 (6597), 266-269, 1996 | 398 | 1996 |
Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase MC Seabra, MS Brown, JL Goldstein Science 259 (5093), 377-381, 1993 | 388 | 1993 |
Controlling the location and activation of Rab GTPases MC Seabra, C Wasmeier Current opinion in cell biology 16 (4), 451-457, 2004 | 383 | 2004 |