Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo T Dignum, B Varnum-Finney, SR Srivatsan, S Dozono, O Waltner, ... Cell reports 36 (11), 2021 | 62 | 2021 |
EWS:: FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma AA Apfelbaum, F Wu, AG Hawkins, B Magnuson, JA Jiménez, SD Taylor, ... Clinical Cancer Research 28 (20), 4466-4478, 2022 | 16 | 2022 |
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity SA Minnie, OG Waltner, KS Ensbey, NS Nemychenkov, CR Schmidt, ... Science immunology 7 (76), eabo3420, 2022 | 14 | 2022 |
TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice SA Minnie, OG Waltner, KS Ensbey, SD Olver, AD Collinge, DP Sester, ... The Journal of clinical investigation 133 (4), 2023 | 11 | 2023 |
The Simularium Viewer: an interactive online tool for sharing spatiotemporal biological models B Lyons, E Isaac, NH Choi, TP Do, J Domingus, J Iwasa, A Leonard, ... Nature Methods 19 (5), 513-515, 2022 | 7 | 2022 |
Cancer-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment ED Wrenn, AA Apfelbaum, ER Rudzinski, X Deng, W Jiang, S Sud, ... Clinical Cancer Research 29 (24), 5140-5154, 2023 | 6 | 2023 |
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks CA Jaeger-Ruckstuhl, Y Lo, E Fulton, OG Waltner, TB Shabaneh, S Simon, ... Immunity 57 (2), 287-302. e12, 2024 | 3 | 2024 |
TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies SA Minnie, OG Waltner, P Zhang, S Takahashi, NS Nemychenkov, ... Science immunology 9 (94), eadg1094, 2024 | 2 | 2024 |
Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD Y Wang, MA Ullah, OG Waltner, SS Bhise, KS Ensbey, CR Schmidt, ... The Journal of clinical investigation 134 (11), 2024 | 1 | 2024 |
Microbiota-specific T cells contribute to graft-versus-host disease after allogeneic stem cell transplantation AC Yeh, M Koyama, O Waltner, SA Minnie, J Boiko, TB Shabaneh, ... Blood 142, 345, 2023 | 1 | 2023 |
Single-Cell Multiomics for Residual Disease Detection in Acute Myelogenous Leukemia after Allogeneic Hematopoietic Cell Transplantation MA Biernacki, O Waltner, SB Kanaan, R Green Gladden, S Bhise, ... Blood 140 (Supplement 1), 10215-10216, 2022 | 1 | 2022 |
Distinct transcriptional signatures distinguish the emergence of multipotent progenitors and hematopoietic stem cells from endothelial precursors in the murine embryo T Dignum, B Varnum-Finney, S Srivatsan, S Dozono, O Waltner, A Heck, ... Blood 136, 7-8, 2020 | 1 | 2020 |
Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation AC Yeh, M Koyama, OG Waltner, SA Minnie, JR Boiko, TB Shabaneh, ... Immunity, 2024 | | 2024 |
IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation P Zhang, P Fleming, CE Andoniou, OG Waltner, SS Bhise, JP Martins, ... The Journal of Clinical Investigation 134 (7), 2024 | | 2024 |
Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution T Ishida, AM Heck, B Varnum-Finney, S Dozono, C Nourigat-McKay, ... bioRxiv, 2023 | | 2023 |
Discrete extracellular matrix-secreting tumor cell subpopulations remodel the Ewing sarcoma tumor microenvironment to promote invasion ED Wrenn, AA Apfelbaum, S Ganapathi, ER Rudzinski, X Deng, N Garcia, ... Cancer Research 83 (7_Supplement), 3531-3531, 2023 | | 2023 |
Single Cell RNA Sequencing Identifies IL-17-and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease JR Boiko, KS Ensbey, CR Schmidt, OG Waltner, SA Minnie, SN Furlan, ... 2023 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2023 | | 2023 |
Abstract B041: Bone microenvironment cues shift Ewing sarcoma cells towards pro-metastatic, ECM-secreting cell states E Wrenn, A Apfelbaum, T Lipson, E Rudzinski, X Deng, K Braun, N Garcia, ... Cancer Research 83 (2_Supplement_2), B041-B041, 2023 | | 2023 |
Clonal Analysis Reveals Functional and Transcriptional Heterogeneity of Self-Renewing Fetal Liver Hematopoietic Stem Cells T Ishida, AM Heck, B Varnum-Finney, S Dozono, C Nourigat-Mckay, ... Blood 140 (Supplement 1), 8574-8575, 2022 | | 2022 |
Single-Cell Multiomics of Pre-and Post-Remission Bone Marrow from a Pediatric Patient with JMML Reveal Distinct Progenitors and Inflammatory Monocytes Which Are Eliminated By … R Green Gladden, S Bhise, SB Kanaan, O Waltner, J Stevens, C Annesley, ... Blood 140 (Supplement 1), 7850-7851, 2022 | | 2022 |