Targeting acetylcholinesterase to treat neurodegeneration U Holzgrabe, P Kapková, V Alptüzün, J Scheiber, E Kugelmann Expert opinion on therapeutic targets 11 (2), 161-179, 2007 | 245 | 2007 |
Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors AS Alpan, S Parlar, L Carlino, AH Tarikogullari, V Alptüzün, HS Güneş Bioorganic & medicinal chemistry 21 (17), 4928-4937, 2013 | 86 | 2013 |
Search for dual function inhibitors for Alzheimer’s disease: Synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Aβ fibril … P Kapková, V Alptüzün, P Frey, E Erciyas, U Holzgrabe Bioorganic & medicinal chemistry 14 (2), 472-478, 2006 | 81 | 2006 |
Synthesis and antimicrobial activity of some pyridinium salts V Alptüzün, S Parlar, H Taşlı, E Erciyas Molecules 14 (12), 5203-5215, 2009 | 70 | 2009 |
Interaction of (benzylidene-hydrazono)-1, 4-dihydropyridines with β-amyloid, acetylcholine, and butyrylcholine esterases V Alptüzün, M Prinz, V Hörr, J Scheiber, K Radacki, A Fallarero, P Vuorela, ... Bioorganic & medicinal chemistry 18 (5), 2049-2059, 2010 | 68 | 2010 |
1, 4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood–brain barrier M Prinz, S Parlar, G Bayraktar, V Alptüzün, E Erciyas, A Fallarero, ... European Journal of Pharmaceutical Sciences 49 (4), 603-613, 2013 | 40 | 2013 |
Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors Z Soyer, S Uysal, S Parlar, AH Tarikogullari Dogan, V Alptuzun Journal of enzyme inhibition and medicinal chemistry 32 (1), 13-19, 2017 | 33 | 2017 |
Mannich‐Benzimidazole Derivatives as Antioxidant and Anticholinesterase Inhibitors: Synthesis, Biological Evaluations, and Molecular Docking Study AS Alpan, G Sarıkaya, G Çoban, S Parlar, G Armagan, V Alptüzün Archiv der Pharmazie 350 (7), e1600351, 2017 | 30 | 2017 |
Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones S Parlar, G Sayar, AH Tarikogullari, SS Karadagli, V Alptuzun, E Erciyas, ... Bioorganic chemistry 87, 888-900, 2019 | 29 | 2019 |
Synthesis and biological activity of pyridinium-type acetylcholinesterase inhibitors V Alptüzün, P Kapková, K Baumann, E Erciyas, U Holzgrabe Journal of pharmacy and pharmacology 55 (10), 1397-1404, 2003 | 29 | 2003 |
Photodynamic antimicrobial activity of new porphyrin derivatives against methicillin resistant Staphylococcus aureus H Taslı, A Akbıyık, N Topaloğlu, V Alptüzün, S Parlar Journal of Microbiology 56, 828-837, 2018 | 27 | 2018 |
Design, synthesis, and in vitro biological evaluation of novel thiazolopyrimidine derivatives as antileishmanial compounds H Istanbullu, G Bayraktar, H Akbaba, I Cavus, G Coban, ... Archiv der Pharmazie 353 (8), 1900325, 2020 | 26 | 2020 |
1H-benzimidazole derivatives as butyrylcholinesterase inhibitors: synthesis and molecular modeling studies G Coban, L Carlino, AH Tarikogullari, S Parlar, G Sarıkaya, V Alptüzün, ... Medicinal Chemistry Research 25, 2005-2014, 2016 | 26 | 2016 |
Multifunctional cholinesterase inhibitors for Alzheimer's disease: synthesis, biological evaluations, and docking studies of o/p‐propoxyphenylsubstituted‐1H‐benzimidazole … G Sarıkaya, G Çoban, S Parlar, AH Tarikogullari, G Armagan, ... Archiv der Pharmazie 351 (8), 1800076, 2018 | 22 | 2018 |
Synthesis and evaluation of pyridinium‐hydrazone derivatives as potential antitumoral agents S Parlar, Y Erzurumlu, R Ilhan, P Ballar Kırmızıbayrak, V Alptüzün, ... Chemical Biology & Drug Design 92 (1), 1198-1205, 2018 | 21 | 2018 |
Synthesis, biological evaluation and molecular docking study of hydrazone-containing pyridinium salts as cholinesterase inhibitors S Parlar, G Bayraktar, AH Tarikogullari, V Alptüzün, E Erciyas Chemical and Pharmaceutical Bulletin 64 (9), 1281-1287, 2016 | 21 | 2016 |
Synthesis and antileishmanial activity of novel pyridinium-hydrazone derivatives V Alptuzun, G Cakiroglu, ME Limoncu, B Erac, M Hosgor-Limoncu, ... Journal of Enzyme Inhibition and Medicinal Chemistry 28 (5), 960-967, 2013 | 19 | 2013 |
Synthesis and cholinesterase inhibitory activity of some phenylacetamide derivatives bearing 1H-pyrazole or 1H-1, 2, 4-triazole A Tarikoğulları, M Çizmecioğlu, M SAylAM, S PArlAr, V AlPTüZün, Z Soyer Marmara Pharmaceutical Journal 20 (1), 21-27, 2016 | 16 | 2016 |
Synthesis and acetylcholinesterase (AChE) inhibitory activity of some N-substituted-5-chloro-2 (3H)-benzoxazolone derivatives Z Soyer, S Parlar, V Alptuzun Marmara Pharmaceutical Journal 17 (1), 15-20, 2013 | 14 | 2013 |
Cooperative Interactions at M2 Muscarinic Acetylcholine Receptors: Structure/Activity Relationships in Stepwise Shortened Bispyridinium- and Bis(Ammonio … R Gilsbach, M Großmüller, V Alptüzün, E Erciyas, C Tränkle, U Holzgrabe, ... Neurochemical research 28, 667-673, 2003 | 13 | 2003 |