Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus W He, GS Tan, CE Mullarkey, AJ Lee, MMW Lam, F Krammer, C Henry, ... Proceedings of the National Academy of Sciences 113 (42), 11931-11936, 2016 | 187 | 2016 |
Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice W He, CJ Chen, CE Mullarkey, JR Hamilton, CK Wong, PE Leon, ... Nature communications 8 (1), 846, 2017 | 164 | 2017 |
Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact PE Leon, W He, CE Mullarkey, MJ Bailey, MS Miller, F Krammer, P Palese, ... Proceedings of the National Academy of Sciences 113 (40), E5944-E5951, 2016 | 129 | 2016 |
Broadly neutralizing hemagglutinin stalk-specific antibodies induce potent phagocytosis of immune complexes by neutrophils in an Fc-dependent manner CE Mullarkey, MJ Bailey, DA Golubeva, GS Tan, R Nachbagauer, W He, ... MBio 7 (5), e01624-16, 2016 | 116 | 2016 |
Broadly neutralizing hemagglutinin stalk-specific antibodies induce potent phagocytosis of immune complexes by neutrophils in an Fc-dependent manner. mBio 7: e01624-16 CE Mullarkey, MJ Bailey, DA Golubeva, GS Tan, R Nachbagauer, W He, ... | 116* | 2016 |
Broadly neutralizing anti-influenza virus antibodies: enhancement of neutralizing potency in polyclonal mixtures and IgA backbones W He, CE Mullarkey, JA Duty, TM Moran, P Palese, MS Miller Journal of virology 89 (7), 3610-3618, 2015 | 99 | 2015 |
Baseline frequency of inflammatory Cxcl9-expressing tumor-associated macrophages predicts response to avelumab treatment Y Qu, J Wen, G Thomas, W Yang, W Prior, W He, P Sundar, X Wang, ... Cell reports 32 (1), 2020 | 73 | 2020 |
Hepatic cells derived from induced pluripotent stem cells of pigtail macaques support hepatitis C virus infection M Sourisseau, O Goldman, W He, JL Gori, HP Kiem, V Gouon–Evans, ... Gastroenterology 145 (5), 966-969. e7, 2013 | 55 | 2013 |
Synthetic toll-like receptor 4 (TLR4) and TLR7 ligands work additively via MyD88 to induce protective antiviral immunity in mice PH Goff, T Hayashi, W He, S Yao, HB Cottam, GS Tan, B Crain, ... Journal of Virology 91 (19), 10.1128/jvi. 01050-17, 2017 | 37 | 2017 |
Measuring the neutralization potency of influenza A virus hemagglutinin stalk/stem-binding antibodies in polyclonal preparations by microneutralization assay W He, CE Mullarkey, MS Miller Methods 90, 95-100, 2015 | 36 | 2015 |
CARMA3 is a host factor regulating the balance of inflammatory and antiviral responses against viral infection C Jiang, Z Zhou, Y Quan, S Zhang, T Wang, X Zhao, C Morrison, ... Cell reports 14 (10), 2389-2401, 2016 | 31 | 2016 |
Autoimmune Variant PTPN22 C1858T Is Associated With Impaired Responses to Influenza Vaccination JN Crabtree, W He, W Guan, M Flage, MS Miller, EJ Peterson The Journal of infectious diseases 214 (2), 248-257, 2016 | 20 | 2016 |
Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice. Nat Commun 8: 846 W He, CJ Chen, CE Mullarkey, JR Hamilton, CK Wong, PE Leon, ... | 17 | 2017 |
CD40 agonist-induced IL-12p40 potentiates hepatotoxicity C Bonnans, G Thomas, W He, B Jung, W Chen, M Liao, J Heyen, ... Journal for immunotherapy of cancer 8 (1), 2020 | 13 | 2020 |
Generation of escape variants of neutralizing influenza virus monoclonal antibodies PE Leon, TJ Wohlbold, W He, MJ Bailey, CJ Henry, PC Wilson, ... JoVE (Journal of Visualized Experiments), e56067, 2017 | 12 | 2017 |
Validation of a clinically relevant humanized mouse model for the safety assessment of 4-1BB agonists utomilumab and urelumab. JG Keck, W He, BS Buetow, A Vitsky, M Liu, J Yang, G Yang, D Cai, ... Journal of Clinical Oncology 40 (16_suppl), e14602-e14602, 2022 | 1 | 2022 |
Abstract LB349: The use of PBMC humanized mice to test the efficacy and safety of antibody and cell-based cancer immunotherapeutics D Rose, W Lee, G Yang, J Yang, M Cheng, W He, B Buetow, A Vitsky, ... Cancer Research 83 (8_Supplement), LB349-LB349, 2023 | | 2023 |
1258 PBMC humanized mouse model with clinical relevance in assessing the safety profile of 4–1BB agonists utomilumab and urelumab D Rose, W He, B Buetow, A Vitsky, M Lui, J Yang, G Yang, J Keck, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
Defining the protective functions of broadly-reactive antibodies against influenza A virus W He Icahn School of Medicine at Mount Sinai, 2016 | | 2016 |