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Xu Liu
标题
引用次数
引用次数
年份
The nuclear receptor superfamily: A structural perspective
ER Weikum, X Liu, EA Ortlund
Protein Science 27 (11), 1876-1892, 2018
4342018
Characterization of a linked Jumonji domain of the KDM5/JARID1 family of histone H3 lysine 4 demethylases
JR Horton, A Engstrom, EL Zoeller, X Liu, JR Shanks, X Zhang, MA Johns, ...
Journal of Biological Chemistry 291 (6), 2631-2646, 2016
1102016
Structural basis for KDM5A histone lysine demethylase inhibition by diverse compounds
JR Horton, X Liu, M Gale, L Wu, JR Shanks, X Zhang, PJ Webber, ...
Cell chemical biology 23 (7), 769-781, 2016
972016
Emerging themes in PDZ domain signaling: structure, function, and inhibition
X Liu, EJ Fuentes
International review of cell and molecular biology 343, 129-218, 2019
672019
The Tiam1 PDZ domain couples to Syndecan1 and promotes cell–matrix adhesion
TR Shepherd, SM Klaus, X Liu, S Ramaswamy, KA DeMali, EJ Fuentes
Journal of molecular biology 398 (5), 730-746, 2010
672010
Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment
X Liu, Y Wang, JS Gutierrez, JM Damsker, K Nagaraju, EP Hoffman, ...
Proceedings of the National Academy of Sciences 117 (39), 24285-24293, 2020
502020
ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair
G Chen, J Chen, Y Qiao, Y Shi, W Liu, Q Zeng, H Xie, X Shi, Y Sun, X Liu, ...
Nucleic acids research 46 (3), 1266-1279, 2018
462018
The structure of the Tiam1 PDZ domain/phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics
X Liu, TR Shepherd, AM Murray, Z Xu, EJ Fuentes
Structure 21 (3), 342-354, 2013
462013
Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation
F Frank, X Liu, EA Ortlund
Proceedings of the National Academy of Sciences 118 (30), e2024685118, 2021
392021
Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests
F Frank, MM Keen, A Rao, L Bassit, X Liu, HB Bowers, AB Patel, ML Cato, ...
Cell 185 (19), 3603-3616. e13, 2022
342022
Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A
JR Horton, CB Woodcock, Q Chen, X Liu, X Zhang, J Shanks, G Rai, ...
Journal of medicinal chemistry 61 (23), 10588-10601, 2018
332018
First high-resolution crystal structures of the glucocorticoid receptor ligand-binding domain–peroxisome proliferator-activated γ coactivator 1-α complex with endogenous and …
X Liu, Y Wang, EA Ortlund
Molecular Pharmacology 96 (4), 408-417, 2019
312019
Distinct roles for conformational dynamics in protein-ligand interactions
X Liu, DC Speckhard, TR Shepherd, YJ Sun, SR Hengel, L Yu, CA Fowler, ...
Structure 24 (12), 2053-2066, 2016
302016
Structural insights into glucocorticoid receptor function
F Frank, EA Ortlund, X Liu
Biochemical Society Transactions 49 (5), 2333-2343, 2021
232021
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling
NE Bruno, JC Nwachukwu, S Srinivasan, CC Nettles, T Izard, Z Jin, ...
Nature Chemical Biology 17 (3), 307-316, 2021
142021
Insights into the action of inhibitor enantiomers against histone lysine demethylase 5A
JR Horton, X Liu, L Wu, K Zhang, J Shanks, X Zhang, G Rai, BT Mott, ...
Journal of medicinal chemistry 61 (7), 3193-3208, 2018
132018
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
P Kapoor-Vazirani, SK Rath, X Liu, Z Shu, NE Bowen, Y Chen, ...
Nature communications 13 (1), 6707, 2022
122022
Proline-rich acidic protein 1 (PRAP1) protects the gastrointestinal epithelium from irradiation-induced apoptosis
AA Wolfarth, X Liu, TM Darby, DJ Boyer, JB Spizman, JA Owens, ...
Cellular and Molecular Gastroenterology and Hepatology 10 (4), 713-727, 2020
112020
Conformational dynamics and cooperativity drive the specificity of a protein-ligand interaction
X Liu, LC Golden, JA Lopez, TR Shepherd, L Yu, EJ Fuentes
Biophysical journal 116 (12), 2314-2330, 2019
112019
A phospholipid mimetic targeting LRH-1 ameliorates colitis
SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ...
Cell Chemical Biology 29 (7), 1174-1186. e7, 2022
92022
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