Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment M Elahy, C Jackaman, JCL Mamo, V Lam, SS Dhaliwal, C Giles, D Nelson, ... Immunity & Ageing 12, 1-9, 2015 | 300 | 2015 |
Blood-brain barrier dysfunction precedes cognitive decline and neurodegeneration in diabetic insulin resistant mouse model: an implication for causal link R Takechi, V Lam, E Brook, C Giles, N Fimognari, A Mooranian, ... Frontiers in aging neuroscience 9, 399, 2017 | 138 | 2017 |
A systematic review of the valproic-acid-induced rodent model of autism D Chaliha, M Albrecht, M Vaccarezza, R Takechi, V Lam, H Al-Salami, ... Developmental neuroscience 42 (1), 12-48, 2020 | 112 | 2020 |
Dietary fats, cerebrovasculature integrity and Alzheimer’s disease risk R Takechi, S Galloway, MMS Pallebage-Gamarallage, V Lam, JCL Mamo Progress in lipid research 49 (2), 159-170, 2010 | 98 | 2010 |
Aging-related changes in blood-brain barrier integrity and the effect of dietary fat R Takechi, MM Pallebage-Gamarallage, V Lam, C Giles, JC Mamo Neurodegenerative Diseases 12 (3), 125-135, 2013 | 71 | 2013 |
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice R Takechi, MM Pallebage-Gamarallage, V Lam, C Giles, JC Mamo Journal of neuroinflammation 10, 1-12, 2013 | 66 | 2013 |
A multimodal spectroscopic imaging method to characterize the metal and macromolecular content of proteinaceous aggregates (“amyloid plaques”) KL Summers, N Fimognari, A Hollings, M Kiernan, V Lam, RJ Tidy, ... Biochemistry 56 (32), 4107-4116, 2017 | 59 | 2017 |
Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype V Lam, R Takechi, MJ Hackett, R Francis, M Bynevelt, LM Celliers, ... PLoS biology 19 (9), e3001358, 2021 | 58 | 2021 |
Probucol prevents blood–brain barrier dysfunction in wild‐type mice induced by saturated fat or cholesterol feeding R Takechi, S Galloway, MM Pallebage‐Gamarallage, V Lam, SS Dhaliwal, ... Clinical and Experimental Pharmacology and Physiology 40 (1), 45-52, 2013 | 58 | 2013 |
Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents M Pallebage-Gamarallage, V Lam, R Takechi, S Galloway, K Clark, ... Lipids in health and disease 11, 1-11, 2012 | 55 | 2012 |
Probucol prevents blood–brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic diet JCL Mamo, V Lam, E Brook, A Mooranian, H Al-Salami, N Fimognari, ... Diabetes and Vascular Disease Research 16 (1), 87-97, 2019 | 51 | 2019 |
Bile acid bio-nanoencapsulation improved drug targeted-delivery and pharmacological effects via cellular flux: 6-months diabetes preclinical study A Mooranian, S Raj Wagle, B Kovacevic, R Takechi, J Mamo, V Lam, ... Scientific Reports 10 (1), 106, 2020 | 50 | 2020 |
Contemporary lipidomic analytics: opportunities and pitfalls C Giles, R Takechi, V Lam, SS Dhaliwal, JCL Mamo Progress in Lipid Research 71, 86-100, 2018 | 38 | 2018 |
Blood-brain barrier disturbances in diabetes-associated dementia: Therapeutic potential for cannabinoids E Brook, J Mamo, R Wong, H Al-Salami, M Falasca, V Lam, R Takechi Pharmacological Research 141, 291-297, 2019 | 36 | 2019 |
FTIR studies of the similarities between pathology induced protein aggregation in vivo and chemically induced protein aggregation ex vivo RJ Tidy, V Lam, N Fimognari, JC Mamo, MJ Hackett Vibrational Spectroscopy 91, 68-76, 2017 | 34 | 2017 |
The serum concentration of the calcium binding protein S100B is positively associated with cognitive performance in older adults V Lam, MA Albrecht, R Takechi, C Giles, AP James, JK Foster, JCL Mamo Frontiers in aging neuroscience 5, 61, 2013 | 33 | 2013 |
Serum 25-hydroxyvitamin D is associated with reduced verbal episodic memory in healthy, middle-aged and older adults V Lam, MA Albrecht, R Takechi, P Prasopsang, YP Lee, JK Foster, ... European journal of nutrition 55, 1503-1513, 2016 | 32 | 2016 |
Long-term supplementation of microencapsulated ursodeoxycholic acid prevents hypertension in a mouse model of insulin resistance H Al-Salami, JC Mamo, A Mooranian, R Negrulj, V Lam, M Elahy, ... Experimental and Clinical Endocrinology & Diabetes 125 (01), 28-32, 2017 | 31 | 2017 |
Antihypertensive agents do not prevent blood–brain barrier dysfunction and cognitive deficits in dietary-induced obese mice JCL Mamo, V Lam, C Giles, SH Coulson, N Fimognari, A Mooranian, ... International Journal of Obesity 41 (6), 926-934, 2017 | 30 | 2017 |
Antioxidants and dementia risk: consideration through a cerebrovascular perspective V Lam, M Hackett, R Takechi Nutrients 8 (12), 828, 2016 | 30 | 2016 |