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Preeti Sharma
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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye, DM Kranz, ...
Science 369 (6508), 1261-1265, 2020
5682020
Engineering interferons and interleukins for cancer immunotherapy
PG Holder, SA Lim, CS Huang, P Sharma, YS Dagdas, B Bulutoglu, ...
Advanced drug delivery reviews 182, 114112, 2022
742022
Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides
P Sharma, VVVR Marada, Q Cai, M Kizerwetter, Y He, SP Wolf, ...
Proceedings of the National Academy of Sciences 117 (26), 15148-15159, 2020
372020
Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity
P Sharma, DM Kranz
Journal of Biological Chemistry 293 (5), 1820-1834, 2018
332018
Multiple cancer-specific antigens are targeted by a chimeric antibody receptor on a single cancer cell
Y He, K Schreiber, SP Wolf, F Wen, C Steentoft, J Zerweck, M Steiner, ...
JCI insight 4 (21), 2019
322019
Recent advances in T-cell engineering for use in immunotherapy
P Sharma, DM Kranz
F1000Research 5, 2016
232016
Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens
P Sharma, N Wang, DM Kranz
Toxins 6 (2), 556-574, 2014
212014
Generation of genetically stable transformants by Agrobacterium using tomato floral buds
MS Sharada, A Kumari, AK Pandey, S Sharma, P Sharma, Y Sreelakshmi, ...
Plant Cell, Tissue and Organ Culture (PCTOC) 129, 299-312, 2017
192017
T-cell receptors engineered de novo for peptide specificity can mediate optimal T-cell activity without self cross-reactivity
P Sharma, DT Harris, JD Stone, DM Kranz
Cancer Immunology Research, canimm. 0035.2019, 2019
142019
A multiplex assay for detection of staphylococcal and streptococcal exotoxins
P Sharma, N Wang, AS Chervin, CL Quinn, JD Stone, DM Kranz
PloS one 10 (8), e0135986, 2015
72015
Characterization of the Staphylococcal enterotoxin A: Vβ receptor interaction using human receptor fragments engineered for high affinity
P Sharma, S Postel, EJ Sundberg, DM Kranz
Protein Engineering, Design & Selection 26 (12), 781-789, 2013
72013
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model
DRE Ranoa, P Sharma, CP Schane, AN Lewis, E Valdez, VVVR Marada, ...
Journal for Immunotherapy of Cancer 11 (5), 2023
52023
T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy
P Sharma, DM Kranz
Critical Reviews™ in Immunology 39 (2), 2019
22019
i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists
MG Romei, B Leonard, ZB Katz, D Le, Y Yang, ES Day, CW Koo, ...
Nature Communications 15 (1), 642, 2024
12024
Engineering Proteins by Combining Deep Mutational Scanning and Yeast Display
P Sharma, E Procko, DM Kranz
Yeast Surface Display, 117-142, 2022
12022
Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen
P Sharma, VVVR Marada, M Kizerwetter, CP Schane, Y He, SP Wolf, ...
Cancer Research 80 (16 Supplement), 3238-3238, 2020
2020
Cancer treatment with 237 car-t cell based therapeutics recognizing the tn epitope
PS Hans Schreiber, David Kranz, Karin Schreiber, Yanran He
WO Patent WO2020056023A1, 2020
2020
Convergence of the specificity and cross-reactivity of multiple T cell receptors isolated against a single cancer peptide/HLA complex
P Sharma, DT Harris, MV Hager, DM Kranz
Cancer Research 78 (13_Supplement), 3581-3581, 2018
2018
Engineering soluble, high affinity T cell receptor domains for detection of staphylococcal and streptococcal exotoxins
P Sharma
University of Illinois at Urbana-Champaign, 2015
2015
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