| Chemical genomics reveals histone deacetylases are required for core regulatory transcription BE Gryder, L Wu, GM Woldemichael, S Pomella, TR Quinn, PMC Park, ... Nature communications 10 (1), 3004, 2019 | 131 | 2019 |
| Synthetic transcription elongation factors license transcription across repressive chromatin GS Erwin, MP Grieshop, A Ali, J Qi, M Lawlor, D Kumar, I Ahmad, ... Science 358 (6370), 1617-1622, 2017 | 118 | 2017 |
| EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma AD Durbin, T Wang, VK Wimalasena, MW Zimmerman, D Li, NV Dharia, ... Cancer discovery 12 (3), 730-751, 2022 | 90 | 2022 |
| BCL2 amplicon loss and transcriptional remodeling drives ABT-199 resistance in B cell lymphoma models X Zhao, Y Ren, M Lawlor, BD Shah, PMC Park, T Lwin, X Wang, K Liu, ... Cancer Cell 35 (5), 752-766. e9, 2019 | 73 | 2019 |
| Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains J Wang, T Erazo, FM Ferguson, DL Buckley, N Gomez, ... ACS chemical biology 13 (9), 2438-2448, 2018 | 58 | 2018 |
| YAP1-mediated suppression of USP31 enhances NFκB activity to promote sarcomagenesis S Ye, MA Lawlor, A Rivera-Reyes, S Egolf, S Chor, K Pak, GE Ciotti, ... Cancer research 78 (10), 2705-2720, 2018 | 52 | 2018 |
| YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma A Rivera-Reyes, S Ye, G E. Marino, S Egolf, G E. Ciotti, S Chor, Y Liu, ... Cell death & disease 9 (11), 1108, 2018 | 39 | 2018 |
| A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma E Pak, EL MacKenzie, X Zhao, MF Pazyra-Murphy, PMC Park, L Wu, ... Neuro-oncology 21 (9), 1150-1163, 2019 | 34 | 2019 |
| Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, R Lumpkin, ... BioRxiv, 2023 | 29 | 2023 |
| Lysine demethylase 5A Is required for MYC-driven transcription in multiple myeloma H Ohguchi, PMC Park, T Wang, BE Gryder, D Ogiya, K Kurata, X Zhang, ... Blood cancer discovery 2 (4), 370-387, 2021 | 24 | 2021 |
| UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ... Molecular cell 83 (15), 2753-2767. e10, 2023 | 20 | 2023 |
| Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma X Zhao, MY Wang, H Jiang, T Lwin, PM Park, J Gao, MB Meads, Y Ren, ... Cell reports 34 (11), 2021 | 14 | 2021 |
| BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes MC Zaiken, R Flynn, KG Paz, SY Rhee, S Jin, FA Mohamed, A Saha, ... Blood, The Journal of the American Society of Hematology 139 (19), 2983-2997, 2022 | 9 | 2022 |
| The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein C Zou, H Yoon, PMC Park, JJ Patten, J Pellman, J Carreiro, JM Tsai, ... Iscience 26 (5), 2023 | 3 | 2023 |
| Polymerization of ZBTB transcription factors regulates chromatin occupancy PMC Park, J Park, J Brown, M Hunkeler, SSR Burman, KA Donovan, ... Molecular Cell 84 (13), 2511-2524. e8, 2024 | 1 | 2024 |
| Small molecules for inducing selective protein degradation and uses thereof J Qi, L Wu, KC Anderson, Y Song, P Park, D Chauhan US Patent 11,802,132, 2023 | 1 | 2023 |
| Arginine methyltransferase 5 (prmt5) degraders and uses thereof J Qi, L Wu, PM Park, LH Sigua US Patent App. 17/917,075, 2023 | 1 | 2023 |
| UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability JM Tsai, JD Aguirre, J Brown, V Focht, YD Li, G Kempf, L Kater, P Galli, ... Blood 140 (Supplement 1), 2968-2969, 2022 | 1 | 2022 |
| Small molecule target bromo/acetyl proteins and uses thereof J Qi, D Li, VK Wimalasena, P Park US Patent App. 17/617,226, 2022 | 1 | 2022 |
| Hdac3 catalytic inhibitor development and uses thereof D Li, P Park, J Qi, L Wu US Patent App. 17/596,466, 2022 | 1 | 2022 |
