The African coelacanth genome provides insights into tetrapod evolution CT Amemiya, J Alföldi, AP Lee, S Fan, H Philippe, I MacCallum, I Braasch, ... Nature 496 (7445), 311-316, 2013 | 751 | 2013 |
CD23/FcεRII: molecular multi-tasking M Acharya, G Borland, AL Edkins, LM Maclellan, J Matheson, BW Ozanne, ... Clinical & Experimental Immunology 162 (1), 12-23, 2010 | 233 | 2010 |
Cancer stem cells in breast cancer and metastasis JC Lawson, GL Blatch, AL Edkins Breast cancer research and treatment 118, 241-254, 2009 | 173 | 2009 |
Human DNAJ in cancer and stem cells JN Sterrenberg, GL Blatch, AL Edkins Cancer letters 312 (2), 129-142, 2011 | 125 | 2011 |
CHIP: a co-chaperone for degradation by the proteasome AL Edkins The Networking of Chaperones by Co-chaperones: Control of Cellular Protein …, 2015 | 110 | 2015 |
Cytotoxicity of lapachol, β-lapachone and related synthetic 1, 4-naphthoquinones against oesophageal cancer cells SN Sunassee, CGL Veale, N Shunmoogam-Gounden, O Osoniyi, ... European Journal of Medicinal Chemistry 62, 98-110, 2013 | 80 | 2013 |
Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells MC Hunter, KL O’Hagan, A Kenyon, KCH Dhanani, E Prinsloo, AL Edkins PloS one 9 (1), e86842, 2014 | 75 | 2014 |
Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro JA de la Mare, JC Lawson, MT Chiwakata, DR Beukes, AL Edkins, ... Investigational New Drugs 30, 2187-2200, 2012 | 75 | 2012 |
Breast cancer: current developments in molecular approaches to diagnosis and treatment JA de la Mare, L Contu, M C Hunter, B Moyo, J N Sterrenberg, ... Recent patents on anti-cancer drug discovery 9 (2), 153-175, 2014 | 70 | 2014 |
Hsp70/Hsp90 organising protein (hop): beyond interactions with chaperones and prion proteins S Baindur-Hudson, AL Edkins, GL Blatch The Networking of Chaperones by Co-chaperones: Control of Cellular Protein …, 2015 | 62 | 2015 |
Fucoidan structure and its impact on glucose metabolism: Implications for diabetes and cancer therapy B Mabate, CD Daub, S Malgas, AL Edkins, BI Pletschke Marine drugs 19 (1), 30, 2021 | 55 | 2021 |
Heat shock proteins as modulators and therapeutic targets of chronic disease: an integrated perspective AL Edkins, JT Price, AG Pockley, GL Blatch Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 54 | 2018 |
Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay JA de la Mare, JN Sterrenberg, MG Sukhthankar, MT Chiwakata, ... Cancer Cell International 13, 1-14, 2013 | 53 | 2013 |
Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model JA de la Mare, T Jurgens, AL Edkins BMC cancer 17, 1-16, 2017 | 45 | 2017 |
Real-time monitoring of 3T3-L1 preadipocyte differentiation using a commercially available electric cell-substrate impedance sensor system AH Kramer, J Joos-Vandewalle, AL Edkins, CL Frost, E Prinsloo Biochemical and biophysical research communications 443 (4), 1245-1250, 2014 | 43 | 2014 |
STAT3 interacts directly with Hsp90 E Prinsloo, AH Kramer, AL Edkins, GL Blatch IUBMB life 64 (3), 266-273, 2012 | 41 | 2012 |
The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells S Aliwaini, J Peres, WL Kröger, A Blanckenberg, J de La Mare, AL Edkins, ... Cancer Letters 357 (1), 206-218, 2015 | 40 | 2015 |
Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines T Willmer, L Contu, GL Blatch, AL Edkins Cancer letters 328 (2), 252-260, 2013 | 38 | 2013 |
Ferrocenyl and organic novobiocin derivatives: Synthesis and their in vitro biological activity M Mbaba, AN Mabhula, N Boel, AL Edkins, M Isaacs, HC Hoppe, ... Journal of inorganic biochemistry 172, 88-93, 2017 | 37 | 2017 |
Hsp90α/β associates with the GSK3β/axin1/phospho-β-catenin complex in the human MCF-7 epithelial breast cancer model LC Cooper, E Prinsloo, AL Edkins, GL Blatch Biochemical and biophysical research communications 413 (4), 550-554, 2011 | 37 | 2011 |