| Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann‐Pick type C disease AR Alvarez, A Klein, J Castro, GI Cancino, J Amigo, M Mosqueira, ... The FASEB Journal 22 (10), 3617-3627, 2008 | 167 | 2008 |
| Relevance of Niemann‐Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice L Amigo, H Mendoza, J Castro, V Quiñones, JF Miquel, S Zanlungo Hepatology 36 (4), 819-828, 2002 | 85 | 2002 |
| MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content E Balboa, J Castro, MJ Pinochet, GI Cancino, N Matías, PJ Sáez, ... Redox biology 12, 274-284, 2017 | 79 | 2017 |
| Npc1 deficiency in the C57BL/6J genetic background enhances Niemann–Pick disease type C spleen pathology J Parra, AD Klein, J Castro, MG Morales, M Mosqueira, I Valencia, ... Biochemical and biophysical research communications 413 (3), 400-406, 2011 | 56 | 2011 |
| Lysosomal vitamin E accumulation in Niemann–Pick type C disease LF Yévenes, A Klein, JF Castro, T Marín, N Leal, F Leighton, AR Alvarez, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (2), 150-160, 2012 | 53 | 2012 |
| Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease J Castro, L Amigo, JF Miquel, C Gälman, F Crovari, A Raddatz, ... Hepatology 45 (5), 1261-1266, 2007 | 53 | 2007 |
| Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice T Marín, P Contreras, JF Castro, D Chamorro, E Balboa, M Bosch-Morató, ... Nutrients 6 (8), 3000-3017, 2014 | 42 | 2014 |
| Disruption in Connexin-Based Communication Is Associated with Intracellular Ca2+ Signal Alterations in Astrocytes from Niemann-Pick Type C Mice PJ Sáez, JA Orellana, N Vega-Riveros, VA Figueroa, DE Hernández, ... PLoS One 8 (8), e71361, 2013 | 40 | 2013 |
| C (− 106) T polymorphism of the aldose reductase gene and the progression rate of diabetic retinopathy P Olmos, MJ Bastías, V Vollrath, L Toro, A Trincado, P Salinas, JC Claro, ... Diabetes research and clinical practice 74 (2), 175-182, 2006 | 39 | 2006 |
| Protein(s) from the Gram-Positive Bacterium Clavibacter michiganensis subsp. michiganensis Induces a Hypersensitive Response in Plants C Alarcon, J Castro, F Munoz, P Arce-Johnson, J Delgado Phytopathology 88 (4), 306-310, 1998 | 39 | 1998 |
| c-Abl inhibition activates TFEB and promotes cellular clearance in a lysosomal disorder PS Contreras, PJ Tapia, L González-Hódar, I Peluso, C Soldati, ... Iscience 23 (11), 2020 | 32 | 2020 |
| Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability D Busso, MJ Oñate-Alvarado, E Balboa, J Castro, C Lizama, G Morales, ... Reproduction, Fertility and Development 26 (4), 609-621, 2014 | 26 | 2014 |
| Genistein activates transcription factor EB and corrects Niemann–Pick C phenotype G Argüello, E Balboa, PJ Tapia, J Castro, MJ Yañez, P Mattar, R Pulgar, ... International Journal of Molecular Sciences 22 (8), 4220, 2021 | 19 | 2021 |
| Deficiency of Niemann‐Pick C1 protein protects against diet‐induced gallstone formation in mice MG Morales, L Amigo, E Balboa, M Acuna, J Castro, H Molina, JF Miquel, ... Liver International 30 (6), 887-897, 2010 | 15 | 2010 |
| c-Abl activation linked to autophagy-lysosomal dysfunction contributes to neurological impairment in Niemann-Pick type A disease T Marín, AE Dulcey, F Campos, C de la Fuente, M Acuña, J Castro, ... Frontiers in Cell and Developmental Biology 10, 844297, 2022 | 14 | 2022 |
| Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones L Amigo, J Castro, JF Miquel, S Zanlungo, S Young, F Nervi Gastroenterology 131 (6), 1870-1878, 2006 | 12 | 2006 |
| Structural and functional analysis of the ASM p. Ala359Asp mutant that causes acid sphingomyelinase deficiency M Acuña, V Castro-Fernández, M Latorre, J Castro, EH Schuchman, ... Biochemical and biophysical research communications 479 (3), 496-501, 2016 | 8 | 2016 |
| Niemann-Pick C2 protein expression regulates lithogenic diet-induced gallstone formation and dietary cholesterol metabolism in mice E Balboa, G Morales, P Aylwin, G Carrasco, L Amigo, J Castro, A Rigotti, ... Lipids 47, 13-25, 2012 | 8 | 2012 |
| Valoración e intervención de la actitud postural en la estática en la población escolar 10-13 años Á Alvárez, J Castro Wanceulen deportiva, 2017 | 7 | 2017 |
| Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice M Acuña, L González-Hódar, L Amigo, J Castro, MG Morales, GI Cancino, ... Journal of hepatology 64 (2), 361-369, 2016 | 7 | 2016 |
