Medicinal chemistry of hERG optimizations: highlights and hang-ups C Jamieson, EM Moir, Z Rankovic, G Wishart Journal of medicinal chemistry 49 (17), 5029-5046, 2006 | 441 | 2006 |
Inhibition of the ubiquitin-proteasome system in Alzheimer's disease YA Lam, CM Pickart, A Alban, M Landon, C Jamieson, R Ramage, ... Proceedings of the National Academy of Sciences 97 (18), 9902-9906, 2000 | 439 | 2000 |
Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor ND Measom, KD Down, DJ Hirst, C Jamieson, ES Manas, VK Patel, ... ACS Medicinal Chemistry Letters 8 (1), 43-48, 2017 | 193 | 2017 |
Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N, N-dimethylformamide DS MacMillan, J Murray, HF Sneddon, C Jamieson, AJB Watson Green Chemistry 15 (3), 596-600, 2013 | 173 | 2013 |
Recent advances in the synthetic chemistry of bicyclo [1.1. 1] pentane J Kanazawa, M Uchiyama Synlett 30 (01), 1-11, 2019 | 142 | 2019 |
Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation KL Wilson, AR Kennedy, J Murray, B Greatrex, C Jamieson, AJB Watson Beilstein journal of organic chemistry 12 (1), 2005-2011, 2016 | 110 | 2016 |
Development of a solvent selection guide for aldehyde-based direct reductive amination processes FI McGonagle, DS MacMillan, J Murray, HF Sneddon, C Jamieson, ... Green chemistry 15 (5), 1159-1165, 2013 | 89 | 2013 |
Development of autotaxin inhibitors: An overview of the patent and primary literature: Miniperspective D Castagna, DC Budd, SJF Macdonald, C Jamieson, AJB Watson Journal of medicinal chemistry 59 (12), 5604-5621, 2016 | 87 | 2016 |
Cyrene as a bio-based solvent for HATU mediated amide coupling KL Wilson, J Murray, C Jamieson, AJB Watson Organic & biomolecular chemistry 16 (16), 2851-2854, 2018 | 76 | 2018 |
Cyrene as a bio-based solvent for the Suzuki–Miyaura cross-coupling KL Wilson, J Murray, C Jamieson, AJB Watson Synlett 29 (05), 650-654, 2018 | 73 | 2018 |
Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol N Caldwell, C Jamieson, I Simpson, AJB Watson Chemical Communications 51 (46), 9495-9498, 2015 | 71 | 2015 |
The Changing Faces of Halogenated Marine Natural Products: Total Synthesis of the Reported Structures of Elatenyne and an Enyne from Laurencia majuscula HM Sheldrake, C Jamieson, JW Burton Angewandte Chemie 118 (43), 7357-7360, 2006 | 71 | 2006 |
Application of ReactArray robotics and design of experiments techniques in optimisation of supported reagent chemistry C Jamieson, MS Congreve, DF Emiabata-Smith, SV Ley, JJ Scicinski Organic process research & development 6 (6), 823-825, 2002 | 68 | 2002 |
Organobase-catalyzed amidation of esters with amino alcohols N Caldwell, C Jamieson, I Simpson, T Tuttle Organic letters 15 (10), 2506-2509, 2013 | 63 | 2013 |
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix EJ Kay, K Paterson, C Riera-Domingo, D Sumpton, JHM Däbritz, ... Nature metabolism 4 (6), 693-710, 2022 | 57 | 2022 |
Replacement of dichloromethane within chromatographic purification: a guide to alternative solvents DS MacMillan, J Murray, HF Sneddon, C Jamieson, AJB Watson Green chemistry 14 (11), 3016-3019, 2012 | 53 | 2012 |
Synthesis of the originally proposed structures of elatenyne and an enyne from Laurencia majuscula HM Sheldrake, C Jamieson, SI Pascu, JW Burton Organic & biomolecular chemistry 7 (2), 238-252, 2009 | 50 | 2009 |
Amidation of esters with amino alcohols using organobase catalysis N Caldwell, PS Campbell, C Jamieson, F Potjewyd, I Simpson, ... The Journal of Organic Chemistry 79 (19), 9347-9354, 2014 | 48 | 2014 |
Development of a sustainable catalytic ester amidation process N Caldwell, C Jamieson, I Simpson, AJB Watson ACS Sustainable Chemistry & Engineering 1 (10), 1339-1344, 2013 | 48 | 2013 |
Recent advances in positive allosteric modulators of the AMPA receptor. JA Morrow, JK Maclean, C Jamieson Current opinion in drug discovery & development 9 (5), 571-579, 2006 | 47 | 2006 |