Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ... The Journal of experimental medicine 201 (4), 591-601, 2005 | 460 | 2005 |
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer B Wu, HM Moulton, PL Iversen, J Jiang, J Li, J Li, CF Spurney, A Sali, ... Proceedings of the National Academy of Sciences 105 (39), 14814-14819, 2008 | 377 | 2008 |
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction K Nagaraju, L Casciola‐Rosen, I Lundberg, R Rawat, S Cutting, ... Arthritis & Rheumatism 52 (6), 1824-1835, 2005 | 370 | 2005 |
Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies K Nagaraju, N Raben, L Loeffler, T Parker, PJ Rochon, E Lee, C Danning, ... Proceedings of the National Academy of Sciences 97 (16), 9209-9214, 2000 | 366 | 2000 |
Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy MD Grounds, HG Radley, GS Lynch, K Nagaraju, A De Luca Neurobiology of disease 31 (1), 1-19, 2008 | 359 | 2008 |
Histidyl–tRNA synthetase and asparaginyl–tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells OMZ Howard, HF Dong, D Yang, N Raben, K Nagaraju, A Rosen, ... The Journal of experimental medicine 196 (6), 781-791, 2002 | 353 | 2002 |
Early onset of inflammation and later involvement of TGFβ in Duchenne muscular dystrophy YW Chen, K Nagaraju, M Bakay, O McIntyre, R Rawat, R Shi, EP Hoffman Neurology 65 (6), 826-834, 2005 | 335 | 2005 |
Targeted disruption of the acid α-glucosidase gene in mice causes an illness with critical features of both infantile and adult human glycogen storage disease type II N Raben, K Nagaraju, E Lee, P Kessler, B Byrne, L Lee, M LaMarca, ... Journal of Biological Chemistry 273 (30), 19086-19092, 1998 | 312 | 1998 |
Behavioral and locomotor measurements using an open field activity monitoring system for skeletal muscle diseases KS Tatem, JL Quinn, A Phadke, Q Yu, H Gordish-Dressman, K Nagaraju JoVE (Journal of Visualized Experiments), e51785, 2014 | 282 | 2014 |
Immune-mediated pathology in Duchenne muscular dystrophy AS Rosenberg, M Puig, K Nagaraju, EP Hoffman, SA Villalta, VA Rao, ... Science translational medicine 7 (299), 299rv4-299rv4, 2015 | 276 | 2015 |
Enzyme replacement therapy in the mouse model of Pompe disease N Raben, M Danon, AL Gilbert, S Dwivedi, B Collins, BL Thurberg, ... Molecular genetics and metabolism 80 (1-2), 159-169, 2003 | 247 | 2003 |
A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli K Nagaraju, N Raben, G Merritt, L Loeffler, K Kirk, P Plotz Clinical & Experimental Immunology 113 (3), 407-414, 1998 | 229 | 1998 |
Sources of variability and effect of experimental approach on expression profiling data interpretation M Bakay, YW Chen, R Borup, P Zhao, K Nagaraju, EP Hoffman BMC bioinformatics 3, 1-12, 2002 | 228 | 2002 |
VBP15, a novel anti‐inflammatory and membrane‐stabilizer, improves muscular dystrophy without side effects CR Heier, JM Damsker, Q Yu, BC Dillingham, T Huynh, ... EMBO molecular medicine 5 (10), 1569-1585, 2013 | 204 | 2013 |
Effect of genetic background on the dystrophic phenotype in mdx mice WD Coley, L Bogdanik, MC Vila, Q Yu, JH Van Der Meulen, ... Human molecular genetics 25 (1), 130-145, 2016 | 201 | 2016 |
Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle R Rawat, TV Cohen, B Ampong, D Francia, A Henriques-Pons, ... The American journal of pathology 176 (6), 2891-2900, 2010 | 195 | 2010 |
Preclinical drug trials in the mdx mouse: Assessment of reliable and sensitive outcome measures CF Spurney, H Gordish‐Dressman, AD Guerron, A Sali, GS Pandey, ... Muscle & Nerve: Official Journal of the American Association of …, 2009 | 195 | 2009 |
Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery Y Aoki, T Yokota, T Nagata, A Nakamura, J Tanihata, T Saito, ... Proceedings of the National Academy of Sciences 109 (34), 13763-13768, 2012 | 186 | 2012 |
Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart CF Spurney, S Knoblach, EE Pistilli, K Nagaraju, GR Martin, EP Hoffman Neuromuscular Disorders 18 (5), 371-381, 2008 | 172 | 2008 |
Replacing acid α-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers N Raben, T Fukuda, AL Gilbert, D De Jong, BL Thurberg, RJ Mattaliano, ... Molecular Therapy 11 (1), 48-56, 2005 | 172 | 2005 |