| Life in 3D is never flat: 3D models to optimise drug delivery KA Fitzgerald, M Malhotra, CM Curtin, FJ O'Brien, CM O'Driscoll Journal of controlled release 215, 39-54, 2015 | 252 | 2015 |
| Innovative collagen nano‐hydroxyapatite scaffolds offer a highly efficient non‐viral gene delivery platform for stem cell‐mediated bone formation CM Curtin, GM Cunniffe, FG Lyons, K Bessho, GR Dickson, GP Duffy, ... Advanced materials 24 (6), 749, 2012 | 237 | 2012 |
| Combinatorial gene therapy accelerates bone regeneration: non-viral dual delivery of VEGF and BMP2 in a collagen-nanohydroxyapatite scaffold. C Curtin, EG Tierney, K McSorley, SA Cryan, G Duffy, F O'Brien Royal College of Surgeons in Ireland, 2015 | 191 | 2015 |
| Mechanosignalling in cartilage: an emerging target for the treatment of osteoarthritis T Hodgkinson, DC Kelly, CM Curtin, FJ O’Brien Nature Reviews Rheumatology 18 (2), 67-84, 2022 | 176 | 2022 |
| Translating the role of osteogenic-angiogenic coupling in bone formation: Highly efficient chitosan-pDNA activated scaffolds can accelerate bone regeneration in critical-sized … RM Raftery, IM Castaño, G Chen, B Cavanagh, B Quinn, CM Curtin, ... Biomaterials 149, 116-127, 2017 | 125 | 2017 |
| The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics KA Fitzgerald, J Guo, EG Tierney, CM Curtin, M Malhotra, R Darcy, ... Biomaterials 66, 53-66, 2015 | 123 | 2015 |
| Development of a gene-activated scaffold platform for tissue engineering applications using chitosan-pDNA nanoparticles on collagen-based scaffolds RM Raftery, EG Tierney, CM Curtin, SA Cryan, FJ O'Brien Journal of Controlled Release 210, 84-94, 2015 | 117 | 2015 |
| Mesenchymal stem cells and osteoarthritis: remedy or accomplice? CM Coleman, C Curtin, FP Barry, C O'Flatharta, JM Murphy Human gene therapy 21 (10), 1239-1250, 2010 | 99 | 2010 |
| A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human … IM Castaño, CM Curtin, G Shaw, JM Murphy, GP Duffy, FJ O'Brien Journal of controlled release 200, 42-51, 2015 | 95 | 2015 |
| Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis I Mencía Castaño, CM Curtin, GP Duffy, FJ O’Brien Scientific Reports 6 (1), 27941, 2016 | 90 | 2016 |
| Content-dependent osteogenic response of nanohydroxyapatite: an in vitro and in vivo assessment within collagen-based scaffolds GM Cunniffe, CM Curtin, EM Thompson, GR Dickson, FJ O’Brien ACS applied materials & interfaces 8 (36), 23477-23488, 2016 | 83 | 2016 |
| Scaffold‐based microRNA therapies in regenerative medicine and cancer CM Curtin, IM Castaño, FJ O'Brien Advanced healthcare materials 7 (1), 1700695, 2018 | 69 | 2018 |
| A physiologically relevant 3D collagen-based scaffold–neuroblastoma cell system exhibits chemosensitivity similar to orthotopic xenograft models C Curtin, JC Nolan, R Conlon, L Deneweth, C Gallagher, YJ Tan, ... Acta biomaterialia 70, 84-97, 2018 | 63 | 2018 |
| Non-viral gene-activated matrices: next generation constructs for bone repair EG Tierney, GP Duffy, SA Cryan, CM Curtin, FJ O’Brien Organogenesis 9 (1), 22-28, 2013 | 60 | 2013 |
| Preclinical models for neuroblastoma: Advances and challenges JC Nolan, T Frawley, J Tighe, H Soh, C Curtin, O Piskareva Cancer letters 474, 53-62, 2020 | 55 | 2020 |
| Formulation and evaluation of anisamide-targeted amphiphilic cyclodextrin nanoparticles to promote therapeutic gene silencing in a 3D prostate cancer bone metastases model JC Evans, M Malhotra, KA Fitzgerald, J Guo, MF Cronin, CM Curtin, ... Molecular pharmaceutics 14 (1), 42-52, 2017 | 48 | 2017 |
| Rapid bone repair with the recruitment of CD206+ M2-like macrophages using non-viral scaffold-mediated miR-133a inhibition of host cells IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ... Acta biomaterialia 109, 267-279, 2020 | 43 | 2020 |
| Scaffold‐Based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair DC Kelly, RM Raftery, CM Curtin, CM O’Driscoll, FJ O’Brien Journal of Orthopaedic Research® 37 (8), 1671-1680, 2019 | 43 | 2019 |
| Harnessing an inhibitory role of miR-16 in osteogenesis by human mesenchymal stem cells for advanced scaffold-based bone tissue engineering I Mencía Castaño, CM Curtin, GP Duffy, FJ O'Brien Tissue Engineering Part A 25 (1-2), 24-33, 2019 | 42 | 2019 |
| Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis KA Fitzgerald, J Guo, RM Raftery, IM Castano, CM Curtin, M Gooding, ... International journal of pharmaceutics 511 (2), 1058-1069, 2016 | 36 | 2016 |
