HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis N Kaniwa, Y Saito, M Aihara, K Matsunaga, M Tohkin, K Kurose, ... Pharmacogenomics 9 (11), 1617-1622, 2008 | 495 | 2008 |
Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1* 6 and* 28 H Minami, K Sai, M Saeki, Y Saito, S Ozawa, K Suzuki, N Kaniwa, ... Pharmacogenetics and genomics 17 (7), 497-504, 2007 | 327 | 2007 |
Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins Y Saito, Y Ihara, MR Leach, MF Cohen-Doyle, DB Williams The EMBO journal 18 (23), 6718-6729, 1999 | 322 | 1999 |
Genetic variants associated with phenytoin-related severe cutaneous adverse reactions WH Chung, WC Chang, YS Lee, YY Wu, CH Yang, HC Ho, MJ Chen, ... Jama 312 (5), 525-534, 2014 | 307 | 2014 |
UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer K Sai, M Saeki, Y Saito, S Ozawa, N Katori, H Jinno, R Hasegawa, ... Clinical Pharmacology & Therapeutics 75 (6), 501-515, 2004 | 297 | 2004 |
Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials … K Kurose, E Sugiyama, Y Saito Drug metabolism and pharmacokinetics 27 (1), 9-54, 2012 | 290 | 2012 |
HLA‐B*1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients N Kaniwa, Y Saito, M Aihara, K Matsunaga, M Tohkin, K Kurose, H Furuya, ... Epilepsia 51 (12), 2461-2465, 2010 | 270 | 2010 |
Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population H Fukushima‐Uesaka, Y Saito, H Watanabe, K Shiseki, M Saeki, ... Human mutation 23 (1), 100-100, 2004 | 236 | 2004 |
Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism E Sugiyama, N Kaniwa, SR Kim, R Kikura-Hanajiri, R Hasegawa, ... Journal of Clinical Oncology 25 (1), 32-42, 2006 | 222 | 2006 |
Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American N Kaniwa, K Kurose, H Jinno, T Tanaka-Kagawa, Y Saito, M Saeki, ... Drug Metabolism and Disposition 33 (3), 458-465, 2005 | 212 | 2005 |
Calnexin discriminates between protein conformational states and functions as a molecular chaperone in vitro Y Ihara, MF Cohen-Doyle, Y Saito, DB Williams Molecular cell 4 (3), 331-341, 1999 | 211 | 1999 |
Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1 S Ozawa, A Soyama, M Saeki, H Fukushima-Uesaka, M Itoda, S Koyano, ... Drug metabolism and pharmacokinetics 19 (2), 83-95, 2004 | 210 | 2004 |
Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects’ gender and age M Ishikawa, K Maekawa, K Saito, Y Senoo, M Urata, M Murayama, ... PloS one 9 (3), e91806, 2014 | 206 | 2014 |
A whole-genome association study of major determinants for allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis in Japanese patients M Tohkin, N Kaniwa, Y Saito, E Sugiyama, K Kurose, J Nishikawa, ... The pharmacogenomics journal 13 (1), 60-69, 2013 | 201 | 2013 |
Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin N Hanioka, S Ozawa, H Jinno, M Ando, Y Saito, J Sawada Xenobiotica 31 (10), 687-699, 2001 | 194 | 2001 |
Chromoscopy during colonoscopy T Fujii, RT Hasegawa, Y Saitoh, D Fleischer, Y Saito, Y Sano, S Kato Endoscopy 33 (12), 1036-1041, 2001 | 187 | 2001 |
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan K Sai, N Kaniwa, M Itoda, Y Saito, R Hasegawa, K Komamura, K Ueno, ... Pharmacogenetics and Genomics 13 (12), 741-757, 2003 | 176 | 2003 |
HLA class I markers in Japanese patients with carbamazepine‐induced cutaneous adverse reactions H Ikeda, Y Takahashi, E Yamazaki, T Fujiwara, N Kaniwa, Y Saito, ... Epilepsia 51 (2), 297-300, 2010 | 173 | 2010 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA‐B) genotype and allopurinol dosing: 2015 update Y Saito, LK Stamp, KE Caudle, MS Hershfield, EM McDonagh, ... Clinical Pharmacology & Therapeutics 99 (1), 36-37, 2016 | 155 | 2016 |
Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism A Soyama, Y Saito, N Hanioka, N MURAYAMA, O NAKAJIMA, N KATORI, ... Biological and Pharmaceutical Bulletin 24 (12), 1427-1430, 2001 | 144 | 2001 |