Glioma stem cells promote radioresistance by preferential activation of the DNA damage response S Bao, Q Wu, RE McLendon, Y Hao, Q Shi, AB Hjelmeland, MW Dewhirst, ... nature 444 (7120), 756-760, 2006 | 7395 | 2006 |
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice P Sonveaux, F Végran, T Schroeder, MC Wergin, J Verrax, ZN Rabbani, ... The Journal of clinical investigation 118 (12), 3930-3942, 2008 | 1901 | 2008 |
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma DM Brizel, SP Scully, JM Harrelson, LJ Layfield, JM Bean, LR Prosnitz, ... Cancer research 56 (5), 941-943, 1996 | 1540 | 1996 |
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck DM Brizel, GS Sibley, LR Prosnitz, RL Scher, MW Dewhirst International Journal of Radiation Oncology* Biology* Physics 38 (2), 285-289, 1997 | 1355 | 1997 |
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response MW Dewhirst, Y Cao, B Moeller Nature Reviews Cancer 8 (6), 425-437, 2008 | 1237 | 2008 |
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules BJ Moeller, Y Cao, CY Li, MW Dewhirst Cancer cell 5 (5), 429-441, 2004 | 1211 | 2004 |
Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia MW Dewhirst, BL Viglianti, M Lora-Michiels, M Hanson, PJ Hoopes International journal of hyperthermia 19 (3), 267-294, 2003 | 1107 | 2003 |
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers MR Dreher, W Liu, CR Michelich, MW Dewhirst, F Yuan, A Chilkoti Journal of the National Cancer Institute 98 (5), 335-344, 2006 | 1082 | 2006 |
A dual-emissive-materials design concept enables tumour hypoxia imaging G Zhang, GM Palmer, MW Dewhirst, CL Fraser Nature materials 8 (9), 747-751, 2009 | 1006 | 2009 |
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model D Needham, G Anyarambhatla, G Kong, MW Dewhirst Cancer research 60 (5), 1197-1201, 2000 | 999 | 2000 |
The multifaceted roles of nitric oxide in cancer. DA Wink, Y Vodovotz, J Laval, F Laval, MW Dewhirst, JB Mitchell Carcinogenesis 19 (5), 711-721, 1998 | 939 | 1998 |
Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size G Kong, RD Braun, MW Dewhirst Cancer research 60 (16), 4440-4445, 2000 | 840 | 2000 |
Thresholds for thermal damage to normal tissues: an update PS Yarmolenko, EJ Moon, C Landon, A Manzoor, DW Hochman, ... International Journal of Hyperthermia 27 (4), 320-343, 2011 | 731 | 2011 |
Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome DM Brizel, RK Dodge, RW Clough, MW Dewhirst Radiotherapy and Oncology 53 (2), 113-117, 1999 | 730 | 1999 |
Randomized trial of hyperthermia and radiation for superficial tumors EL Jones, JR Oleson, LR Prosnitz, TV Samulski, Z Vujaskovic, D Yu, ... Journal of clinical oncology 23 (13), 3079-3085, 2005 | 727 | 2005 |
The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors D Needham, MW Dewhirst Advanced drug delivery reviews 53 (3), 285-305, 2001 | 721 | 2001 |
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer DM Brizel, T Schroeder, RL Scher, S Walenta, RW Clough, MW Dewhirst, ... International Journal of Radiation Oncology* Biology* Physics 51 (2), 349-353, 2001 | 693 | 2001 |
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release G Kong, G Anyarambhatla, WP Petros, RD Braun, OM Colvin, D Needham, ... Cancer research 60 (24), 6950-6957, 2000 | 663 | 2000 |
Transport of drugs from blood vessels to tumour tissue MW Dewhirst, TW Secomb Nature Reviews Cancer 17 (12), 738-750, 2017 | 612 | 2017 |
Drug targeting using thermally responsive polymers and local hyperthermia DE Meyer, BC Shin, GA Kong, MW Dewhirst, A Chilkoti Journal of controlled release 74 (1-3), 213-224, 2001 | 572 | 2001 |