Comprehensive molecular profiling of lung adenocarcinoma Cancer Genome Atlas Research Network Nature 511 (7511), 543-550, 2014 | 3900 | 2014 |
Comprehensive genomic characterization of head and neck squamous cell carcinomas Cancer Genome Atlas Network Nature 517 (7536), 576-582, 2015 | 3286 | 2015 |
Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2223 | 2018 |
Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive BiomarkersMutation of PI3K Pathway in Head and Neck Cancer VWY Lui, ML Hedberg, H Li, BS Vangara, K Pendleton, Y Zeng, Y Lu, ... Cancer discovery 3 (7), 761-769, 2013 | 650 | 2013 |
A pan-cancer proteomic perspective on The Cancer Genome Atlas R Akbani, PKS Ng, HMJ Werner, M Shahmoradgoli, F Zhang, Z Ju, W Liu, ... Nature communications 5 (1), 1-15, 2014 | 556 | 2014 |
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ... Cancer Cell 31 (6), 820-832. e3, 2017 | 530 | 2017 |
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer Y Wang, X Xu, D Maglic, MT Dill, K Mojumdar, PKS Ng, KJ Jeong, ... Cell reports 25 (5), 1304-1317. e5, 2018 | 373 | 2018 |
Systematic Functional Annotation of Somatic Mutations in Cancer PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ... Cancer cell 33 (3), 450-462. e10, 2018 | 252 | 2018 |
Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers C Sun, Y Fang, J Yin, J Chen, Z Ju, D Zhang, X Chen, CP Vellano, ... Science translational medicine 9 (392), 2017 | 207 | 2017 |
The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens TF Chan, KM Ji, AKY Yim, XY Liu, JW Zhou, RQ Li, KY Yang, J Li, M Li, ... Journal of Allergy and Clinical Immunology 135 (2), 539-548, 2015 | 197 | 2015 |
Cloning and expression analysis of two distinct HIF-alpha isoforms–gcHIF-1alpha and gcHIF-4alpha–from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus SHW Law, RSS Wu, PKS Ng, RMK Yu, RYC Kong BMC molecular biology 7, 1-13, 2006 | 156 | 2006 |
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer VWY Lui, ND Peyser, PKS Ng, J Hritz, Y Zeng, Y Lu, H Li, L Wang, ... Proceedings of the National Academy of Sciences 111 (3), 1114-1119, 2014 | 116 | 2014 |
Naturally occurring neomorphic pik3r1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors LWT Cheung, S Yu, D Zhang, J Li, PKS Ng, N Panupinthu, S Mitra, Z Ju, ... Cancer cell 26 (4), 479-494, 2014 | 90 | 2014 |
A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell CarcinomaPI3K Pathway Inhibition … T Mazumdar, LA Byers, PKS Ng, GB Mills, S Peng, L Diao, YH Fan, ... Molecular cancer therapeutics 13 (11), 2738-2750, 2014 | 86 | 2014 |
RET fusion as a novel driver of medullary thyroid carcinoma EG Grubbs, PKS Ng, J Bui, NL Busaidy, K Chen, JE Lee, X Lu, H Lu, ... The Journal of Clinical Endocrinology & Metabolism 100 (3), 788-793, 2015 | 82 | 2015 |
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death VWY Lui, EYL Wong, K Ho, PKS Ng, CPY Lau, SKW Tsui, CM Tsang, ... Oncogene 30 (9), 1127-1134, 2011 | 69 | 2011 |
Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model RMK Yu, EXH Chen, RYC Kong, PKS Ng, HOL Mok, DWT Au BMC Molecular Biology 7, 1-12, 2006 | 69 | 2006 |
Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo [a] pyrene (BaP) RMK Yu, PKS Ng, T Tan, DLH Chu, RSS Wu, RYC Kong Aquatic toxicology 90 (3), 235-242, 2008 | 66 | 2008 |
Characterization of a hypoxia-responsive leptin receptor (omLepR L) cDNA from the marine medaka (Oryzias melastigma) MML Wong, RMK Yu, PKS Ng, SHW Law, AKC Tsang, RYC Kong Marine pollution bulletin 54 (6), 797-803, 2007 | 60 | 2007 |
Molecular landscape of BRAF-mutant NSCLC reveals an association between clonality and driver mutations and identifies targetable non-V600 driver mutations MV Negrao, VM Raymond, RB Lanman, JP Robichaux, J He, MB Nilsson, ... Journal of Thoracic Oncology 15 (10), 1611-1623, 2020 | 58 | 2020 |