| Cell viability assays TL Riss, RA Moravec, AL Niles, S Duellman, HA Benink, TJ Worzella, ... Assay guidance manual [Internet], 2016 | 2608 | 2016 |
| Assay guidance manual TL Riss, RA Moravec, AL Niles, S Duellman, HA Benink, TJ Worzella, ... Cell Viability Assays. Eli Lilly Company and the national center for …, 2013 | 376 | 2013 |
| A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers AL Niles, RA Moravec, PE Hesselberth, MA Scurria, WJ Daily, TL Riss Analytical biochemistry 366 (2), 197-206, 2007 | 269 | 2007 |
| Elevated tryptase, nerve growth factor, neurotrophin-3 and glial cell line-derived neurotrophic factor levels in the urine of interstitial cystitis and bladder cancer patients AJ OKRAGLY, AL NILES, R SABAN, D SCHMIDT, RL HOFFMAN, ... The Journal of urology 161 (2), 438-442, 1999 | 258 | 1999 |
| Target engagement and drug residence time can be observed in living cells with BRET MB Robers, ML Dart, CC Woodroofe, CA Zimprich, TA Kirkland, ... Nature communications 6 (1), 10091, 2015 | 252 | 2015 |
| In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screening AL Niles, RA Moravec, TL Riss Current chemical genomics 3, 33, 2009 | 210 | 2009 |
| Update on in vitro cytotoxicity assays for drug development AL Niles, RA Moravec, TL Riss Expert opinion on drug discovery 3 (6), 655-669, 2008 | 205 | 2008 |
| Cytotoxicity assays: in vitro methods to measure dead cells T Riss, A Niles, R Moravec, N Karassina, J Vidugiriene | 157 | 2019 |
| Cytotoxicity testing: measuring viable cells, dead cells, and detecting mechanism of cell death TL Riss, RA Moravec, AL Niles Mammalian cell viability: methods and protocols, 103-114, 2011 | 156 | 2011 |
| Assay guidance manual [Internet] TL Riss, RA Moravec, AL Niles, S Duellman, HA Benink, TJ Worzella, ... Bethesda (MD): Eli Lilly & Company and the National Center for Advancing …, 2004 | 121 | 2004 |
| A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker MH Cho, A Niles, R Huang, J Inglese, CP Austin, T Riss, M Xia Toxicology in vitro 22 (4), 1099-1106, 2008 | 120 | 2008 |
| Cell viability assays. 2013 may 1 [updated 2016 Jul 1] TL Riss, RA Moravec, AL Niles, S Duellman, HA Benink, TJ Worzella, ... Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the …, 2004 | 120 | 2004 |
| A real-time, bioluminescent annexin V assay for the assessment of apoptosis K Kupcho, J Shultz, R Hurst, J Hartnett, W Zhou, T Machleidt, J Grailer, ... Apoptosis 24, 184-197, 2019 | 93 | 2019 |
| Definition of the extended substrate specificity determinants for β-tryptases I and II JL Harris, A Niles, K Burdick, M Maffitt, BJ Backes, JA Ellman, I Kuntz, ... Journal of Biological Chemistry 276 (37), 34941-34947, 2001 | 83 | 2001 |
| Timing your apoptosis assays T Sundquist, R Moravec, A Niles, M O’Brien, T Riss Cell Notes 16, 18-21, 2006 | 77 | 2006 |
| Non-invasive diagnostic method for interstitial cystitis and bladder cancer M Haak-Frendscho, AJ Okragly, AL Niles, R Saban US Patent 6,008,003, 1999 | 76 | 1999 |
| Bioluminescent assays for ADMET JJ Cali, A Niles, MP Valley, MA O'Brien, TL Riss, J Shultz Expert opinion on drug metabolism & toxicology 4 (1), 103-120, 2008 | 72 | 2008 |
| Recombinant human mast cell tryptase beta: stable expression in Pichia pastoris and purification of fully active enzyme AL Niles, M Maffitt, M Haak‐Frendscho, CJ Wheeless, DA Johnson Biotechnology and applied biochemistry 28 (2), 125-131, 1998 | 61 | 1998 |
| Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death R Swiss, A Niles, JJ Cali, S Nadanaciva, Y Will Toxicology In Vitro 27 (6), 1789-1797, 2013 | 55 | 2013 |
| Selecting cell-based assays for drug discovery screening T Riss, R Moravec, A Niles Cell notes 13, 16-21, 2005 | 53 | 2005 |
