Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain J Marschallinger, T Iram, M Zardeneta, SE Lee, B Lehallier, MS Haney, ... Nature neuroscience 23 (2), 194-208, 2020 | 704 | 2020 |
Ageing hallmarks exhibit organ-specific temporal signatures N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ... Nature 583 (7817), 596-602, 2020 | 390 | 2020 |
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 H Yousef, CJ Czupalla, D Lee, MB Chen, AN Burke, KA Zera, J Zandstra, ... Nature medicine 25 (6), 988-1000, 2019 | 312 | 2019 |
Activation of the STING-dependent type I interferon response reduces microglial reactivity and neuroinflammation V Mathur, R Burai, RT Vest, LN Bonanno, B Lehallier, ME Zardeneta, ... Neuron 96 (6), 1290-1302. e6, 2017 | 138 | 2017 |
Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer’s disease–like mice S Prokop, KR Miller, N Drost, S Handrick, V Mathur, J Luo, A Wegner, ... Journal of Experimental Medicine 212 (11), 1811-1818, 2015 | 115 | 2015 |
Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation Z Ding, V Mathur, PP Ho, ML James, KM Lucin, A Hoehne, H Alabsi, ... Journal of Experimental Medicine 211 (2), 189-198, 2014 | 72 | 2014 |
Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury SS Holden, FC Grandi, O Aboubakr, B Higashikubo, FS Cho, AH Chang, ... Science 373 (6560), eabj2685, 2021 | 68 | 2021 |
Ssa1 overexpression and [PIN+] variants cure [PSI+] by dilution of aggregates V Mathur, JY Hong, SW Liebman Journal of molecular biology 390 (2), 155-167, 2009 | 51 | 2009 |
Analyzing the Birth and Propagation of Two Distinct Prions, [PSI+] and [Het-s]y, in Yeast V Mathur, V Taneja, Y Sun, SW Liebman Molecular biology of the cell 21 (9), 1449-1461, 2010 | 50 | 2010 |
Localization of HET-S to the cell periphery, not to [Het-s] aggregates, is associated with [Het-s]–HET-S toxicity V Mathur, C Seuring, R Riek, SJ Saupe, SW Liebman Molecular and cellular biology 32 (1), 139-153, 2012 | 47 | 2012 |
Ganciclovir derivatives for modulating innate and adaptive immunity and for use in immunotherapy R Burai, H Lashuel, V Mathur, A Wyss-Coray US Patent 9,809,597, 2017 | 20 | 2017 |
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain J Marschallinger, T Iram, M Zardeneta, SE Lee, B Lehallier, MS Haney, ... Nature neuroscience 23 (2), 294-294, 2020 | 16 | 2020 |
Acute and late administration of colony stimulating factor 1 attenuates chronic cognitive impairment following mild traumatic brain injury in mice L Li, L Yerra, B Chang, V Mathur, A Nguyen, J Luo Brain, behavior, and immunity 94, 274-288, 2021 | 9 | 2021 |
Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier H Yousef, CJ Czupalla, D Lee, A Burke, M Chen, J Zandstra, E Berber, ... BioRxiv, 242198, 2018 | 9 | 2018 |
A new colour assay for [URE3] prion in a genetic background used to score for the [PSI+] prion JY Hong, V Mathur, SW Liebman Yeast 28 (7), 555-560, 2011 | 9 | 2011 |
Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma Y Sun, D Wirta, W Murahashi, V Mathur, S Sankaranarayanan, LK Taylor, ... Ophthalmology Science 3 (2), 100290, 2023 | 6 | 2023 |
Pharmacokinetic and target engagement measures of ANX007, an anti-C1q antibody fragment, following intravitreal administration in nonhuman primates A Grover, S Sankaranarayanan, V Mathur, P Suri, H Qiu, ... Investigative Ophthalmology & Visual Science 64 (2), 3-3, 2023 | 6 | 2023 |
Pharmacokinetics and target engagement of intravitreal administration of ANX007, an anti-C1q antibody fragment, in nonhuman primates A Grover, S Sankaranarayanan, V Mathur, P Suri, Y Andrews-Zwilling, ... Investigative Ophthalmology & Visual Science 62 (8), 219-219, 2021 | 3 | 2021 |
Inhibiting C1q improves compound muscle action potential and reduces neuronal damage in the SOD1G93A mouse model (P1-13.004) Y Andrews-Zwilling, V Mathur, L Kuhn, S Sankaranarayanan, ... Neurology 98 (18 Supplement), 2022 | 1 | 2022 |
I11 Pharmacologic inhibition of the classical complement pathway enhances neuronal function and HD R6/2 mouse survival A Tassoni, V Mathur, J Vereen, E Cahir-McFarland, S Sankaranarayanan, ... Journal of Neurology, Neurosurgery & Psychiatry 92 (Suppl 1), A52-A52, 2021 | 1 | 2021 |