| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13274* | 2021 |
| A molecular mechanism for the effect of lithium on development. PS Klein, DA Melton Proceedings of the National Academy of Sciences 93 (16), 8455-8459, 1996 | 2950 | 1996 |
| Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen CJ Phiel, F Zhang, EY Huang, MG Guenther, MA Lazar, PS Klein Journal of Biological Chemistry 276 (39), 36734-36741, 2001 | 2113 | 2001 |
| GSK-3α regulates production of Alzheimer's disease amyloid-β peptides CJ Phiel, CA Wilson, VMY Lee, PS Klein Nature 423 (6938), 435-439, 2003 | 1589 | 2003 |
| Activation of the Wnt signaling pathway: a molecular mechanism for lithium action CM Hedgepeth, LJ Conrad, J Zhang, HC Huang, VMY Lee, PS Klein Developmental biology 185 (1), 82-91, 1997 | 805 | 1997 |
| Nuclear receptor Rev-erbα is a critical lithium-sensitive component of the circadian clock L Yin, J Wang, PS Klein, MA Lazar Science 311 (5763), 1002-1005, 2006 | 698 | 2006 |
| Molecular targets of lithium action CJ Phiel, PS Klein Annual review of pharmacology and toxicology 41 (1), 789-813, 2001 | 664 | 2001 |
| Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3 M Hong, DCR Chen, PS Klein, VMY Lee Journal of Biological Chemistry 272 (40), 25326-25332, 1997 | 605 | 1997 |
| Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium: evidence for autoregulation of GSK-3 F Zhang, CJ Phiel, L Spece, N Gurvich, PS Klein Journal of Biological Chemistry 278 (35), 33067-33077, 2003 | 579 | 2003 |
| Histone deacetylase is a target of valproic acid-mediated cellular differentiation N Gurvich, OM Tsygankova, JL Meinkoth, PS Klein Cancer research 64 (3), 1079-1086, 2004 | 574 | 2004 |
| O2 regulates stem cells through Wnt/β-catenin signalling J Mazumdar, WT O'brien, RS Johnson, JC LaManna, JC Chavez, ... Nature cell biology 12 (10), 1007-1013, 2010 | 534 | 2010 |
| A Chemoattractant Receptor Controls Development in Dictyostelium discoideum PS Klein, TJ Sun, CL Saxe III, AR Kimmel, RL Johnson, PN Devreotes Science 241 (4872), 1467-1472, 1988 | 525 | 1988 |
| Glycogen synthase kinase-3β haploinsufficiency mimics the behavioral and molecular effects of lithium WT O'Brien, ADA Harper, F Jové, JR Woodgett, S Maretto, S Piccolo, ... Journal of Neuroscience 24 (30), 6791-6798, 2004 | 521 | 2004 |
| Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH K Zhang, MB Jordan, RA Marsh, JA Johnson, D Kissell, J Meller, ... Blood, The Journal of the American Society of Hematology 118 (22), 5794-5798, 2011 | 457 | 2011 |
| The Frizzled family: receptors for multiple signal transduction pathways HC Huang, PS Klein Genome biology 5, 1-7, 2004 | 412 | 2004 |
| Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis U Rothbächer, MN Laurent, MA Deardorff, PS Klein, KWY Cho, SE Fraser The EMBO journal 19 (5), 1010-1022, 2000 | 353 | 2000 |
| Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder RJ Schloesser, J Huang, PS Klein, HK Manji Neuropsychopharmacology 33 (1), 110-133, 2008 | 312 | 2008 |
| Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability Y Kirino, N Kim, M de Planell-Saguer, E Khandros, S Chiorean, PS Klein, ... Nature cell biology 11 (5), 652-658, 2009 | 282 | 2009 |
| nakedcuticle encodes an inducible antagonist of Wnt signalling W Zeng, KA Wharton Jr, JA Mack, K Wang, M Gadbaw, K Suyama, ... Nature 403 (6771), 789-795, 2000 | 255 | 2000 |
| Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways J Huang, M Nguyen-McCarty, EO Hexner, G Danet-Desnoyers, PS Klein Nature medicine 18 (12), 1778-1785, 2012 | 252 | 2012 |
