| The structural modification of natural products for novel drug discovery H Yao, J Liu, S Xu, Z Zhu, J Xu Expert opinion on drug discovery 12 (2), 121-140, 2017 | 233 | 2017 |
| Discovery of novel quinoline–chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity W Li, F Xu, W Shuai, H Sun, H Yao, C Ma, S Xu, H Yao, Z Zhu, DH Yang, ... Journal of medicinal chemistry 62 (2), 993-1013, 2018 | 115 | 2018 |
| A novel potent anticancer compound optimized from a natural oridonin scaffold induces apoptosis and cell cycle arrest through the mitochondrial pathway S Xu, H Yao, S Luo, YK Zhang, DH Yang, D Li, G Wang, M Hu, Y Qiu, ... Journal of Medicinal Chemistry 60 (4), 1449-1468, 2017 | 98 | 2017 |
| Probing the anticancer action of oridonin with fluorescent analogues: visualizing subcellular localization to mitochondria S Xu, S Luo, H Yao, H Cai, X Miao, F Wu, DH Yang, X Wu, W Xie, H Yao, ... Journal of Medicinal Chemistry 59 (10), 5022-5034, 2016 | 59 | 2016 |
| Discovery of novel tacrine–pyrimidone hybrids as potent dual AChE/GSK-3 inhibitors for the treatment of Alzheimer’s disease H Yao, G Uras, P Zhang, S Xu, Y Yin, J Liu, S Qin, X Li, S Allen, R Bai, ... Journal of Medicinal Chemistry 64 (11), 7483-7506, 2021 | 51 | 2021 |
| Design, synthesis and antimycobacterial activity evaluation of natural oridonin derivatives S Xu, D Li, L Pei, H Yao, C Wang, H Cai, H Yao, X Wu, J Xu Bioorganic & medicinal chemistry letters 24 (13), 2811-2814, 2014 | 47 | 2014 |
| Synthesis and antimycobacterial evaluation of natural oridonin and its enmein-type derivatives S Xu, L Pei, D Li, H Yao, H Cai, H Yao, X Wu, J Xu Fitoterapia 99, 300-306, 2014 | 44 | 2014 |
| Development of alectinib-based PROTACs as novel potent degraders of anaplastic lymphoma kinase (ALK) S Xie, Y Sun, Y Liu, X Li, X Li, W Zhong, F Zhan, J Zhu, H Yao, DH Yang, ... Journal of medicinal chemistry 64 (13), 9120-9140, 2021 | 42 | 2021 |
| Design, synthesis, and biological evaluation of NAD (P) H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation S Xu, H Yao, L Pei, M Hu, D Li, Y Qiu, G Wang, L Wu, H Yao, Z Zhu, J Xu European journal of medicinal chemistry 132, 310-321, 2017 | 40 | 2017 |
| Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain W Li, Y Yin, W Shuai, F Xu, H Yao, J Liu, K Cheng, J Xu, Z Zhu, S Xu Bioorganic chemistry 83, 380-390, 2019 | 39 | 2019 |
| Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities W Li, Y Yin, H Yao, W Shuai, H Sun, S Xu, J Liu, H Yao, Z Zhu, J Xu European Journal of Medicinal Chemistry 157, 1068-1080, 2018 | 34 | 2018 |
| Novel anticancer oridonin derivatives possessing a diazen-1-ium-1, 2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies S Xu, G Wang, Y Lin, Y Zhang, L Pei, H Yao, M Hu, Y Qiu, Z Huang, ... Bioorganic & Medicinal Chemistry Letters 26 (12), 2795-2800, 2016 | 34 | 2016 |
| Discovery of norbornene as a novel hydrophobic tag applied in protein degradation S Xie, F Zhan, J Zhu, Y Sun, H Zhu, J Liu, J Chen, Z Zhu, DH Yang, ... Angewandte Chemie 135 (13), e202217246, 2023 | 32 | 2023 |
| N-Heterocyclic Carbene Catalytic [4 + 2] Cyclization of 3-Alkylenyloxindoles with Enals: γ-Carbon Activation for Enantioselective Assembly of Spirocarbocyclic … H Yao, Y Zhou, X Chen, P Zhang, J Xu, H Liu The Journal of Organic Chemistry 81 (19), 8888-8899, 2016 | 32 | 2016 |
| 6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents S Xu, H Yao, M Hu, D Li, Z Zhu, W Xie, H Yao, L Wu, ZS Chen, J Xu Journal of natural products 80 (9), 2391-2398, 2017 | 31 | 2017 |
| Identification of a potent oridonin analogue for treatment of triple-negative breast cancer H Yao, S Xie, X Ma, J Liu, H Wu, A Lin, H Yao, D Li, S Xu, DH Yang, ... Journal of Medicinal Chemistry 63 (15), 8157-8178, 2020 | 29 | 2020 |
| Synthesis, biological evaluation of fluorescent 23-hydroxybetulinic acid probes, and their cellular localization studies H Yao, G Wei, Y Liu, H Yao, Z Zhu, W Ye, X Wu, J Xu, S Xu ACS Medicinal Chemistry Letters 9 (10), 1030-1034, 2018 | 29 | 2018 |
| Organocatalytic 1, 5-trifluoromethylthio-sulfonylation of vinylcyclopropane mediated by visible light in the water phase J Liu, H Yao, X Li, H Wu, A Lin, H Yao, J Xu, S Xu Organic Chemistry Frontiers 7 (11), 1314-1320, 2020 | 27 | 2020 |
| Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease Y Liu, G Uras, I Onuwaje, W Li, H Yao, S Xu, X Li, X Li, J Phillips, S Allen, ... European Journal of Medicinal Chemistry 235, 114305, 2022 | 19 | 2022 |
| Molecular glues modulate protein functions by inducing protein aggregation: A promising therapeutic strategy of small molecules for disease treatment H Wu, H Yao, C He, Y Jia, Z Zhu, S Xu, D Li, J Xu Acta Pharmaceutica Sinica B 12 (9), 3548-3566, 2022 | 18 | 2022 |
