| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth T Hitosugi, S Kang, MG Vander Heiden, TW Chung, S Elf, K Lythgoe, ... Science signaling 2 (97), ra73-ra73, 2009 | 851 | 2009 |
| Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ... Cancer cell 22 (5), 585-600, 2012 | 434 | 2012 |
| Glutaminolysis as a target for cancer therapy L Jin, GN Alesi, S Kang Oncogene 35 (28), 3619-3625, 2016 | 411 | 2016 |
| Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism T Hitosugi, J Fan, TW Chung, K Lythgoe, X Wang, J Xie, Q Ge, TL Gu, ... Molecular cell 44 (6), 864-877, 2011 | 345 | 2011 |
| Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ... Cancer cell 27 (2), 257-270, 2015 | 340 | 2015 |
| Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex J Fan, C Shan, HB Kang, S Elf, J Xie, M Tucker, TL Gu, M Aguiar, ... Molecular cell 53 (4), 534-548, 2014 | 292 | 2014 |
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484-1496, 2015 | 269 | 2015 |
| Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD+ redox homeostasis in cancer cells J Fan, T Hitosugi, TW Chung, J Xie, Q Ge, TL Gu, RD Polakiewicz, ... Molecular and cellular biology 31 (24), 4938-4950, 2011 | 262 | 2011 |
| The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancer L Jin, J Chun, C Pan, A Kumar, G Zhang, Y Ha, D Li, GN Alesi, Y Kang, ... Molecular cell 69 (1), 87-99. e7, 2018 | 247 | 2018 |
| Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis L Jin, J Chun, C Pan, GN Alesi, D Li, KR Magliocca, Y Kang, ZG Chen, ... Oncogene 36 (27), 3797-3806, 2017 | 242 | 2017 |
| p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells S Kang, S Elf, K Lythgoe, T Hitosugi, J Taunton, W Zhou, L Xiong, D Wang, ... The Journal of clinical investigation 120 (4), 1165-1177, 2010 | 180 | 2010 |
| FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway S Kang, S Dong, TL Gu, A Guo, MS Cohen, S Lonial, HJ Khoury, ... Cancer cell 12 (3), 201-214, 2007 | 163 | 2007 |
| New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of Thoracic Oncology 15 (4), 520-540, 2020 | 158 | 2020 |
| Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ... Molecular cell 59 (3), 345-358, 2015 | 148 | 2015 |
| Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 144 | 2014 |
| MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ... Cancer cell 34 (2), 315-330. e7, 2018 | 112 | 2018 |
| Selective targeting of distinct active site nucleophiles by irreversible Src-family kinase inhibitors NN Gushwa, S Kang, J Chen, J Taunton Journal of the American Chemical Society 134 (50), 20214-20217, 2012 | 107 | 2012 |
| Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival X Liu, Z Liu, SW Jang, Z Ma, K Shinmura, S Kang, S Dong, J Chen, ... Proceedings of the National Academy of Sciences 104 (23), 9679-9684, 2007 | 105 | 2007 |
| Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, ... Nature communications 4 (1), 1-10, 2013 | 98 | 2013 |
| Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth J Fan, R Lin, S Xia, D Chen, SE Elf, S Liu, Y Pan, H Xu, Z Qian, M Wang, ... Molecular cell 64 (5), 859-874, 2016 | 96 | 2016 |
