Gene essentiality and synthetic lethality in haploid human cells VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ... Science 350 (6264), 1092-1096, 2015 | 871 | 2015 |
Vasohibins encode tubulin detyrosinating activity J Nieuwenhuis, A Adamopoulos, OB Bleijerveld, A Mazouzi, E Stickel, ... Science 358 (6369), 1453-1456, 2017 | 235 | 2017 |
PLA2G16 represents a switch between entry and clearance of Picornaviridae J Staring, E von Castelmur, VA Blomen, LG van den Hengel, ... Nature 541 (7637), 412-416, 2017 | 195 | 2017 |
Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling M Brockmann, VA Blomen, J Nieuwenhuis, E Stickel, M Raaben, ... Nature 546 (7657), 307-311, 2017 | 130 | 2017 |
Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy J Zirin, J Nieuwenhuis, N Perrimon PLoS biology 11 (11), e1001708, 2013 | 123 | 2013 |
The tubulin detyrosination cycle: function and enzymes J Nieuwenhuis, TR Brummelkamp Trends in cell biology 29 (1), 80-92, 2019 | 92 | 2019 |
Nedd4-binding protein 1 and TNFAIP3-interacting protein 1 control MHC-1 display in neuroblastoma L Spel, J Nieuwenhuis, R Haarsma, E Stickel, OB Bleijerveld, M Altelaar, ... Cancer Research 78 (23), 6621-6631, 2018 | 48 | 2018 |
Posttranslational modification of microtubules by the MATCAP detyrosinase L Landskron, J Bak, A Adamopoulos, K Kaplani, M Moraiti, ... Science 376 (6595), eabn6020, 2022 | 42 | 2022 |
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism A Loregger, M Raaben, J Nieuwenhuis, JME Tan, LT Jae, ... Nature communications 11 (1), 1128, 2020 | 35 | 2020 |
Regulators of Autophagosome Formation in Drosophila Muscles J Zirin, J Nieuwenhuis, A Samsonova, R Tao, N Perrimon PLoS Genetics 11 (2), e1005006, 2015 | 34 | 2015 |
Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1–SVBP A Adamopoulos, L Landskron, T Heidebrecht, F Tsakou, OB Bleijerveld, ... Nature Structural & Molecular Biology 26 (7), 567-570, 2019 | 28 | 2019 |
Reconstruction of the cell entry pathway of an extinct virus LR Robinson-McCarthy, KR McCarthy, M Raaben, S Piccinotti, ... PLoS pathogens 14 (8), e1007123, 2018 | 25 | 2018 |
Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents NM Gerhards, VA Blomen, M Mutlu, J Nieuwenhuis, D Howald, ... Molecular oncology 12 (6), 953-971, 2018 | 13 | 2018 |
Assays to identify genetic elements affecting phenotype TR Brummelkamp, JDM Nieuwenhuis, LT Jae, M Brockmann, VA Blomen, ... US Patent App. 16/438,102, 2019 | | 2019 |
Assays to identify genetic elements affecting phenotype TR Brummelkamp, JDM Nieuwenhuis, LT Jae, M Brockmann, VA Blomen, ... US Patent 10,351,845, 2019 | | 2019 |
Crystal structure of the VASH1/SVBP complex, a tubulin tyrosine carboxypeptidase A Adamopoulos, L Landskron, T Heidebrect, F Tsakou, OB Bleijerveld, ... STRUCTURAL STUDIES OF TUBULIN MODIFYING ENZYMES 26 (7), 59, 2019 | | 2019 |
Universaliteit in een diverse Europese Unie, de geschiedenis van het mensenrechtenvertoog in Europese omgang met Poolse identiteitspolitiek CJ Nieuwenhuis | | 2018 |
Ultra-deep genome mutagenesis in haploid human cells LT Jae, VA Blomen, M Raaben, P Majek, AS Herbert, M Brockmann, ... Glycobiology, 1378-1378, 2016 | | 2016 |
Autophagy and Intracellular Pathogens: the Killer, the Victim and the Suspects JDM Nieuwenhuis | | 2012 |
1 Regulation of Syntaxin 17 during Autophagosome Maturation 3 Centriole Biogenesis: Symmetry Breaking and Site Selection B Grünwald, B Schoeps, A Krüger, M Piper, R Gronostajski, G Messina, ... | | |