| Regulation of pH by carbonic anhydrase 9 mediates survival of pancreatic cancer cells with activated KRAS in response to hypoxia PC McDonald, SC Chafe, WS Brown, S Saberi, M Swayampakula, ... Gastroenterology 157 (3), 823-837, 2019 | 175 | 2019 |
| The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells S Fiorcari, WS Brown, BW McIntyre, Z Estrov, R Maffei, S O’Brien, ... PloS one 8 (12), e83830, 2013 | 111 | 2013 |
| Spleen tyrosine kinase–mediated autophagy is required for epithelial–mesenchymal plasticity and metastasis in breast cancer A Shinde, SD Hardy, D Kim, SS Akhand, MK Jolly, WH Wang, ... Cancer research 79 (8), 1831-1843, 2019 | 105 | 2019 |
| Targeting Constitutively Activated β1 Integrins Inhibits Prostate Cancer Metastasis YC Lee, JK Jin, CJ Cheng, CF Huang, JH Song, M Huang, WS Brown, ... Molecular Cancer Research 11 (4), 405-417, 2013 | 103 | 2013 |
| Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors SC Chafe, FS Vizeacoumar, G Venkateswaran, O Nemirovsky, S Awrey, ... Science advances 7 (35), eabj0364, 2021 | 84 | 2021 |
| Covalent targeting of fibroblast growth factor receptor inhibits metastatic breast cancer WS Brown, L Tan, A Smith, NS Gray, MK Wendt Molecular cancer therapeutics 15 (9), 2096-2106, 2016 | 76 | 2016 |
| Overcoming adaptive resistance to KRAS and MEK inhibitors by co-targeting mTORC1/2 complexes in pancreatic cancer WS Brown, PC McDonald, O Nemirovsky, S Awrey, SC Chafe, ... Cell Reports Medicine 1 (8), 2020 | 68 | 2020 |
| FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition WS Brown, SS Akhand, MK Wendt Oncotarget 7 (50), 83424, 2016 | 52 | 2016 |
| Clustering T‐cell GM1 lipid rafts increases cellular resistance to shear on fibronectin through changes in integrin affinity and cytoskeletal dynamics JS Mitchell, WS Brown, DG Woodside, P Vanderslice, BW McIntyre Immunology and cell biology 87 (4), 324-336, 2009 | 45 | 2009 |
| Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion P Vanderslice, RJ Biediger, DG Woodside, WS Brown, S Khounlo, ... Journal of Biological Chemistry 288 (27), 19414-19428, 2013 | 31 | 2013 |
| Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer A Abdullah, SS Akhand, JSP Paez, W Brown, L Pan, S Libring, M Badamy, ... Oncogene 40 (2), 322-333, 2021 | 29 | 2021 |
| Biased signaling downstream of epidermal growth factor receptor regulates proliferative versus apoptotic response to ligand R Ali, W Brown, SC Purdy, VJ Davisson, MK Wendt Cell death & disease 9 (10), 976, 2018 | 29 | 2018 |
| B-Raf regulation of integrin α4β1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cells WS Brown, JS Khalili, TG Rodriguez-Cruz, G Lizee, BW McIntyre Journal of Biological Chemistry 289 (33), 23141-23153, 2014 | 17 | 2014 |
| Synthesis and evaluation of an anti-MLC1× anti-CD90 bispecific antibody for targeting and retaining bone-marrow-derived multipotent stromal cells in infarcted myocardium CW Gundlach IV, A Caivano, M da Graca Cabreira-Hansen, ... Bioconjugate chemistry 22 (8), 1706-1714, 2011 | 16 | 2011 |
| Selective inhibition of STAT3 phosphorylation using a nuclear-targeted kinase inhibitor MD Bartolowits, W Brown, R Ali, AM Pedley, Q Chen, KE Harvey, ... ACS chemical biology 12 (9), 2371-2378, 2017 | 13 | 2017 |
| Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation WS Brown, MK Wendt Breast cancer research 16, 1-3, 2014 | 10 | 2014 |
| Syntaxin4-Munc18c interaction promotes breast tumor invasion and metastasis by regulating MT1-MMP trafficking MI Brasher, SC Chafe, PC McDonald, O Nemirovsky, G Gorshtein, ... Molecular Cancer Research 20 (3), 434-445, 2022 | 7 | 2022 |
| 2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1 R Carreño, WS Brown, D Li, JA Hernandez, Y Wang, TK Kim, JW Craft, ... Journal of Biological Chemistry 285 (43), 32860-32868, 2010 | 7 | 2010 |
| A Carbonic Anhydrase IX/SLC1A5 axis regulates glutamine metabolism dependent ferroptosis in hypoxic tumor cells G Venkateswaran, PC McDonald, SC Chafe, WS Brown, ZJ Gerbec, ... Molecular Cancer Therapeutics 22 (10), 1228-1242, 2023 | 6 | 2023 |
| The PI3 Kinase δ Inhibitor, CAL-101 (GS-1101), Inhibits Chronic Lymphocytic Leukemia (CLL) Cell Survival in Endothelial and Marrow Stromal Cell Co-Cultures. S Fiorcari, WS Brown, BW McIntyre, S O'Brien, M Sivina, J Hoellenriegel, ... Blood 118 (21), 1769, 2011 | 6 | 2011 |
