Molecular digital data storage using DNA L Ceze, J Nivala, K Strauss Nature Reviews Genetics 20 (8), 456-466, 2019 | 467 | 2019 |
CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria SL Shipman, J Nivala, JD Macklis, GM Church Nature 547 (7663), 345-349, 2017 | 391 | 2017 |
Unfoldase-mediated protein translocation through an α-hemolysin nanopore J Nivala, DB Marks, M Akeson Nature biotechnology 31 (3), 247-250, 2013 | 372 | 2013 |
Molecular recordings by directed CRISPR spacer acquisition SL Shipman, J Nivala, JD Macklis, GM Church Science 353 (6298), aaf1175, 2016 | 248 | 2016 |
Discrimination among protein variants using an unfoldase-coupled nanopore J Nivala, L Mulroney, G Li, J Schreiber, M Akeson ACS nano 8 (12), 12365-12375, 2014 | 123 | 2014 |
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array PB Stranges, M Palla, S Kalachikov, J Nivala, M Dorwart, S Kumar, ... Proceedings of the National Academy of Sciences 113 (44), E6749-E6756, 2016 | 66 | 2016 |
Synthetic DNA applications in information technology LC Meiser, BH Nguyen, YJ Chen, J Nivala, K Strauss, L Ceze, RN Grass Nature communications 13 (1), 352, 2022 | 64 | 2022 |
Reversible thrombin detection by aptamer functionalized STING sensors P Actis, A Rogers, J Nivala, B Vilozny, RA Seger, O Jejelowo, ... Biosensors and Bioelectronics 26 (11), 4503-4507, 2011 | 64 | 2011 |
Recording gene expression order in DNA by CRISPR addition of retron barcodes S Bhattarai-Kline, SK Lear, CB Fishman, SC Lopez, ER Lockshin, ... Nature 608 (7921), 217-225, 2022 | 36 | 2022 |
Rapid and robust assembly and decoding of molecular tags with DNA-based nanopore signatures K Doroschak, K Zhang, M Queen, A Mandyam, K Strauss, L Ceze, ... Nature communications 11 (1), 5454, 2020 | 36 | 2020 |
Multiplexed direct detection of barcoded protein reporters on a nanopore array N Cardozo, K Zhang, K Doroschak, A Nguyen, Z Siddiqui, N Bogard, ... Nature biotechnology 40 (1), 42-46, 2022 | 33 | 2022 |
Improvement of a potential anthrax therapeutic by computational protein design SJ Wu, CB Eiben, JH Carra, I Huang, D Zong, P Liu, CT Wu, J Nivala, ... Journal of Biological Chemistry 286 (37), 32586-32592, 2011 | 22 | 2011 |
Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration J Nivala, SL Shipman, GM Church Nature microbiology 3 (3), 310-318, 2018 | 21 | 2018 |
Design of stimulus-responsive two-state hinge proteins F Praetorius, PJY Leung, MH Tessmer, A Broerman, C Demakis, ... Science 381 (6659), 754-760, 2023 | 18 | 2023 |
De novo design of high-affinity protein binders to bioactive helical peptides SV Torres, PJY Leung, ID Lutz, P Venkatesh, JL Watson, F Hink, ... Biorxiv, 2022.12. 10.519862, 2022 | 17 | 2022 |
De novo design of high-affinity binders of bioactive helical peptides S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ... Nature 626 (7998), 435-442, 2024 | 16 | 2024 |
Herding cats: Label-based approaches in protein translocation through nanopore sensors for single-molecule protein sequence analysis K Motone, N Cardozo, J Nivala Iscience 24 (9), 2021 | 14 | 2021 |
Not if but when nanopore protein sequencing meets single-cell proteomics K Motone, J Nivala Nature Methods 20 (3), 336-338, 2023 | 13 | 2023 |
Multiplex single-molecule kinetics of nanopore-coupled polymerases M Palla, S Punthambaker, B Stranges, F Vigneault, J Nivala, D Wiegand, ... Acs Nano 15 (1), 489-502, 2020 | 13 | 2020 |
A nanopore interface for higher bandwidth DNA computing K Zhang, YJ Chen, D Wilde, K Doroschak, K Strauss, L Ceze, G Seelig, ... Nature Communications 13 (1), 4904, 2022 | 9 | 2022 |