Contributions of counter-charge in a potassium channel voltage-sensor domain SA Pless, JD Galpin, AP Niciforovic, CA Ahern Nature Chemical Biology 7 (9), 617-623, 2011 | 101 | 2011 |
Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels SA Pless, JD Galpin, A Frankel, CA Ahern Nature Communications 2, 351, 2011 | 100 | 2011 |
A cation-π interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue SA Pless, KS Millen, AP Hanek, JW Lynch, HA Lester, SCR Lummis, ... The Journal of Neuroscience 28 (43), 10937-10942, 2008 | 90 | 2008 |
Atomic basis for therapeutic activation of neuronal potassium channels RY Kim, MC Yau, JD Galpin, G Seebohm, CA Ahern, SA Pless, HT Kurata Nature communications 6, 2015 | 86 | 2015 |
Unnatural Amino Acids as Probes of Ligand-Receptor Interactions and Their Conformational Consequences SA Pless, CA Ahern Annual review of pharmacology and toxicology 53, 211-229, 2013 | 81 | 2013 |
Conformational variability of the glycine receptor M2 domain in response to activation by different agonists SA Pless, MI Dibas, HA Lester, JW Lynch Journal of Biological Chemistry 282 (49), 36057-36067, 2007 | 79 | 2007 |
Ligand-specific conformational changes in the α1 glycine receptor ligand-binding domain SA Pless, JW Lynch Journal of Biological Chemistry 284 (23), 15847-15856, 2009 | 72 | 2009 |
Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels SA Pless, JD Galpin, AP Niciforovic, HT Kurata, CA Ahern eLife 2, 2013 | 65 | 2013 |
Intermediate state trapping of a voltage sensor JJ Lacroix, SA Pless, L Maragliano, FV Campos, JD Galpin, CA Ahern, ... The Journal of general physiology 140 (6), 635-652, 2012 | 62 | 2012 |
The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium HC Chua, M Wulf, C Weidling, LP Rasmussen, SA Pless Science Advances 6 (17), eaaz3154, 2020 | 58 | 2020 |
Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes T Lynagh, Y Mikhaleva, JM Colding, JC Glover, SA Pless Proceedings of the National Academy of Sciences, 201806614, 2018 | 58 | 2018 |
Principles of agonist recognition in Cys-loop receptors T Lynagh, SA Pless Frontiers in physiology 5, 2014 | 57 | 2014 |
PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels RY Kim, SA Pless, HT Kurata Proceedings of the National Academy of Sciences 114 (45), E9702-E9711, 2017 | 55 | 2017 |
A selectivity filter at the intracellular end of the acid-sensing ion channel pore T Lynagh, E Flood, C Boiteux, M Wulf, VV Komnatnyy, JM Colding, ... eLife 6, 2017 | 55 | 2017 |
A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists SA Pless, AP Hanek, KL Price, JW Lynch, HA Lester, DA Dougherty, ... Molecular pharmacology 79 (4), 742-748, 2011 | 51 | 2011 |
Structure of the human sodium leak channel NALCN M Kschonsak, HC Chua, CL Noland, C Weidling, T Clairfeuille, ... Nature, 1-10, 2020 | 47 | 2020 |
Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains SA Pless, FD Elstone, AP Niciforovic, JD Galpin, R Yang, HT Kurata, ... The Journal of general physiology 143 (5), 645-656, 2014 | 43 | 2014 |
ILLUMINATING THE STRUCTURE AND FUNCTION OF CYS‐LOOP RECEPTORS SA Pless, JW Lynch Clinical and Experimental Pharmacology and Physiology 35 (10), 1137-1142, 2008 | 41 | 2008 |
Acid-sensing ion channels as potential therapeutic targets SA Heusser, SA Pless Trends in pharmacological sciences, 2021 | 37 | 2021 |
Magnitude of a conformational change in the glycine receptor β1-β2 loop is correlated with agonist efficacy SA Pless, JW Lynch Journal of Biological Chemistry 284 (40), 27370-27376, 2009 | 37 | 2009 |