A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine MD Ruben, G Wu, DF Smith, RE Schmidt, LJ Francey, YY Lee, RC Anafi, ... Science Translational Medicine 10 (458), eaat8806, 2018 | 260 | 2018 |
Guidelines for genome-scale analysis of biological rhythms ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ... Journal of biological rhythms 32 (5), 380-393, 2017 | 233 | 2017 |
Dosing time matters MD Ruben, DF Smith, GF FitzGerald, JB Hogenesch Science 365 (6453), 547-549, 2019 | 193 | 2019 |
Population-level rhythms in human skin with implications for circadian medicine G Wu, MD Ruben, RE Schmidt, LJ Francey, DF Smith, RC Anafi, ... Proceedings of the National Academy of Sciences 115 (48), 12313-12318, 2018 | 119 | 2018 |
Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders SD Ginsberg, I Elarova, M Ruben, F Tan, SE Counts, JH Eberwine, ... Neurochemical Research 29, 1053-1064, 2004 | 109 | 2004 |
A mechanism for circadian control of pacemaker neuron excitability M Ruben, MD Drapeau, D Mizrak, J Blau Journal of biological rhythms 27 (5), 353-364, 2012 | 60 | 2012 |
Electrical activity can impose time of day on the circadian transcriptome of pacemaker neurons D Mizrak, M Ruben, GN Myers, K Rhrissorrakrai, KC Gunsalus, J Blau Current Biology 22 (20), 1871-1880, 2012 | 56 | 2012 |
Drosophila pacemaker neurons require g protein signaling and GABAergic inputs to generate twenty-four hour behavioral rhythms D Dahdal, DC Reeves, M Ruben, MH Akabas, J Blau Neuron 68 (5), 964-977, 2010 | 51 | 2010 |
A population-based gene expression signature of molecular clock phase from a single epidermal sample G Wu, MD Ruben, LJ Francey, DF Smith, JD Sherrill, JE Oblong, KJ Mills, ... Genome medicine 12, 1-12, 2020 | 44 | 2020 |
A large-scale study reveals 24-h operational rhythms in hospital treatment MD Ruben, LJ Francey, Y Guo, G Wu, EB Cooper, AS Shah, ... Proceedings of the National Academy of Sciences 116 (42), 20953-20958, 2019 | 29 | 2019 |
Circadian dysregulation: the next frontier in obstructive sleep apnea research DC von Allmen, LJ Francey, GM Rogers, MD Ruben, AP Cohen, G Wu, ... Otolaryngology–Head and Neck Surgery 159 (6), 948-955, 2018 | 28 | 2018 |
Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease G Wu, YY Lee, EM Gulla, A Potter, J Kitzmiller, MD Ruben, N Salomonis, ... Elife 10, e63003, 2021 | 27 | 2021 |
Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data G Wu, LJ Francey, MD Ruben, JB Hogenesch Bioinformatics 37 (23), 4581-4583, 2021 | 14 | 2021 |
When should you take your medicines? DF Smith, MD Ruben, LJ Francey, OJ Walch, JB Hogenesch Journal of biological rhythms 34 (6), 582-583, 2019 | 13 | 2019 |
Sleep and circadian medicine: time of day in the neurologic clinic MD Ruben, JB Hogenesch, DF Smith Neurologic clinics 37 (3), 615-629, 2019 | 13 | 2019 |
Genome-wide studies of time of day in the brain: Design and analysis G Wu, MD Ruben, Y Lee, J Li, ME Hughes, JB Hogenesch Brain Science Advances 6 (2), 92-105, 2020 | 12 | 2020 |
A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine. Sci Transl Med. 2018; 10 (458): eaat8806 MD Ruben, G Wu, DF Smith, RE Schmidt, LJ Francey, YY Lee, RC Anafi, ... Epub 2018/09/14. doi: 10.1126/scitranslmed. aat8806. PubMed PMID: 30209245, 0 | 12 | |
What is there left to learn about the Drosophila clock? J Blau, F Blanchard, B Collins, D Dahdal, A Knowles, D Mizrak, M Ruben Cold Spring Harbor symposia on quantitative biology 72, 243-250, 2007 | 11 | 2007 |
Circadian rhythms: move over neurons—astrocytes mediate SCN clock function MD Ruben, JB Hogenesch Current Biology 27 (9), R350-R352, 2017 | 10 | 2017 |
An in silico genome-wide screen for circadian clock strength in human samples G Wu, MD Ruben, LJ Francey, YY Lee, RC Anafi, JB Hogenesch Bioinformatics 38 (24), 5375-5382, 2022 | 9 | 2022 |