In vivo excision of HIV-1 provirus by saCas9 and multiplex single-guide RNAs in animal models C Yin, T Zhang, X Qu, Y Zhang, R Putatunda, X Xiao, F Li, W Xiao, H Zhao, ... Molecular Therapy 25 (5), 1168-1186, 2017 | 333 | 2017 |
Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid C He, X Qu, L Cui, J Wang, JX Kang Proceedings of the National Academy of Sciences 106 (27), 11370-11375, 2009 | 286 | 2009 |
Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells X Qu, P Wang, D Ding, L Li, H Wang, L Ma, X Zhou, S Liu, S Lin, X Wang, ... Nucleic acids research 41 (16), 7771-7782, 2013 | 187 | 2013 |
Dual blockade of CXCL12-CXCR4 and PD-1–PD-L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironment Y Zeng, B Li, Y Liang, PM Reeves, X Qu, C Ran, Q Liu, MV Callahan, ... The FASEB Journal 33 (5), 6596, 2019 | 152 | 2019 |
Delta‐6‐desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue MC Pender‐Cudlip, KJ Krag, D Martini, J Yu, A Guidi, SS Skinner, ... Cancer science 104 (6), 760-764, 2013 | 113 | 2013 |
Specific reactivation of latent HIV-1 by dCas9-SunTag-VP64-mediated guide RNA targeting the HIV-1 promoter H Ji, Z Jiang, P Lu, L Ma, C Li, H Pan, Z Fu, X Qu, P Wang, J Deng, ... Molecular Therapy 24 (3), 508-521, 2016 | 88 | 2016 |
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb P Lu, X Qu, Y Shen, Z Jiang, P Wang, H Zeng, H Ji, J Deng, X Yang, X Li, ... Scientific reports 6 (1), 24100, 2016 | 83 | 2016 |
Inhibiting delta-6 desaturase activity suppresses tumor growth in mice C He, X Qu, J Wan, R Rong, L Huang, C Cai, K Zhou, Y Gu, SY Qian, ... PLoS One 7 (10), e47567, 2012 | 74 | 2012 |
Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation D Ding, X Qu, L Li, X Zhou, S Liu, S Lin, P Wang, S Liu, C Kong, X Wang, ... Virology 440 (2), 182-189, 2013 | 62 | 2013 |
Reactivation of HIV-1 from latency by an ingenol derivative from Euphorbia kansui P Wang, P Lu, X Qu, Y Shen, H Zeng, X Zhu, Y Zhu, X Li, H Wu, J Xu, H Lu, ... Scientific reports 7 (1), 1-15, 2017 | 51 | 2017 |
Two cellular microRNAs, miR-196b and miR-1290, contribute to HIV-1 latency P Wang, X Qu, X Zhou, Y Shen, H Ji, Z Fu, J Deng, P Lu, W Yu, H Lu, ... Virology 486, 228-238, 2015 | 47 | 2015 |
Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB H Ying, Y Zhang, X Zhou, X Qu, P Wang, S Liu, D Lu, H Zhu PloS one 7 (11), e48832, 2012 | 39 | 2012 |
AMD3100 augments the efficacy of mesothelin-targeted, immune-activating VIC-008 in mesothelioma by modulating intratumoral immunosuppression B Li, Y Zeng, PM Reeves, C Ran, Q Liu, X Qu, Y Liang, Z Liu, J Yuan, ... Cancer immunology research 6 (5), 539-551, 2018 | 36 | 2018 |
Specific reactivation of latent HIV-1 with designer zinc-finger transcription factors targeting the HIV-1 5′-LTR promoter P Wang, X Qu, X Wang, X Zhu, H Zeng, H Chen, H Zhu Gene therapy 21 (5), 490-495, 2014 | 32 | 2014 |
Nicotine-enhanced stemness and epithelial-mesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice T Li, J Zhang, J Zhang, N Zhang, Y Zeng, S Tang, Z Tao, X Qu, J Jia, ... Oncotarget 9 (1), 591, 2018 | 27 | 2018 |
As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB P Wang, X Qu, X Wang, L Liu, X Zhu, H Zeng, H Zhu Antiviral research 100 (3), 688-697, 2013 | 27 | 2013 |
Zinc-finger nucleases induced by HIV-1 Tat excise HIV-1 from the host genome in infected and latently infected cells H Ji, P Lu, B Liu, X Qu, Y Wang, Z Jiang, X Yang, Y Zhong, H Yang, H Pan, ... Molecular Therapy-Nucleic Acids 12, 67-74, 2018 | 25 | 2018 |
Zinc finger nuclease: a new approach for excising HIV-1 proviral DNA from infected human T cells X Qu, P Wang, D Ding, X Wang, G Zhang, X Zhou, L Liu, X Zhu, H Zeng, ... Molecular biology reports 41, 5819-5827, 2014 | 22 | 2014 |
Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET) Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, ... Acta Pharmaceutica Sinica B 9 (6), 1204-1215, 2019 | 21 | 2019 |
Designed transcription activator-like effector proteins efficiently induced the expression of latent HIV-1 in latently infected cells X Wang, P Wang, Z Fu, H Ji, X Qu, H Zeng, X Zhu, J Deng, P Lu, S Zha, ... AIDS research and human retroviruses 31 (1), 98-106, 2015 | 20 | 2015 |