Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ... Nature communications 7 (1), 12632, 2016 | 931 | 2016 |
PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression S Jiao, W Xia, H Yamaguchi, Y Wei, MK Chen, JM Hsu, JL Hsu, WH Yu, ... Clinical Cancer Research 23 (14), 3711-3720, 2017 | 874 | 2017 |
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway DF Lee, HP Kuo, CT Chen, JM Hsu, CK Chou, Y Wei, HL Sun, LY Li, ... Cell 130 (3), 440-455, 2007 | 818 | 2007 |
Deubiquitination and stabilization of PD-L1 by CSN5 SO Lim, CW Li, W Xia, JH Cha, LC Chan, Y Wu, SS Chang, WC Lin, ... Cancer cell 30 (6), 925-939, 2016 | 658 | 2016 |
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis J Hou, R Zhao, W Xia, CW Chang, Y You, JM Hsu, L Nie, Y Chen, ... Nature cell biology 22 (10), 1264-1275, 2020 | 629 | 2020 |
Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1 CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, ... Cancer cell 33 (2), 187-201. e10, 2018 | 480 | 2018 |
EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling CJ Chang, JY Yang, W Xia, CT Chen, X Xie, CH Chao, WA Woodward, ... Cancer cell 19 (1), 86-100, 2011 | 478 | 2011 |
Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization Q Ding, X He, JM Hsu, W Xia, CT Chen, LY Li, DF Lee, JC Liu, Q Zhong, ... Molecular and cellular biology 27 (11), 4006-4017, 2007 | 472 | 2007 |
The crosstalk of mTOR/S6K1 and Hedgehog pathways Y Wang, Q Ding, CJ Yen, W Xia, JG Izzo, JY Lang, CW Li, JL Hsu, ... Cancer cell 21 (3), 374-387, 2012 | 398 | 2012 |
Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth Y Yang, CW Li, LC Chan, Y Wei, JM Hsu, W Xia, JH Cha, J Hou, JL Hsu, ... Cell research 28 (8), 862-864, 2018 | 393 | 2018 |
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion JM Hsu, W Xia, YH Hsu, LC Chan, WH Yu, JH Cha, CT Chen, HW Liao, ... Nature communications 9 (1), 1908, 2018 | 354 | 2018 |
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy R Yang, L Sun, CF Li, YH Wang, J Yao, H Li, M Yan, WC Chang, JM Hsu, ... Nature communications 12 (1), 832, 2021 | 349 | 2021 |
Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer L Nie, HJ Wu, JM Hsu, SS Chang, AM LaBaff, CW Li, Y Wang, JL Hsu, ... American journal of translational research 4 (2), 127, 2012 | 269 | 2012 |
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion LC Chan, CW Li, W Xia, JM Hsu, HH Lee, JH Cha, HL Wang, WH Yang, ... The Journal of clinical investigation 129 (8), 3324-3338, 2019 | 265 | 2019 |
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins YN Wang, H Yamaguchi, JM Hsu, MC Hung Oncogene 29 (28), 3997-4006, 2010 | 265 | 2010 |
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation JM Hsu, CT Chen, CK Chou, HP Kuo, LY Li, CY Lin, HJ Lee, YN Wang, ... Nature cell biology 13 (2), 174-181, 2011 | 260 | 2011 |
Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3β activity and associates with poor prognosis in human breast cancer Q Ding, X He, W Xia, JM Hsu, CT Chen, LY Li, DF Lee, JY Yang, X Xie, ... Cancer research 67 (10), 4564-4571, 2007 | 245 | 2007 |
Posttranslational modifications of PD-L1 and their applications in cancer therapy JM Hsu, CW Li, YJ Lai, MC Hung Cancer research 78 (22), 6349-6353, 2018 | 225 | 2018 |
Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics H Yamaguchi, JM Hsu, WH Yang, MC Hung Nature Reviews Clinical Oncology 19 (5), 287-305, 2022 | 218 | 2022 |
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer Q Ding, L Huo, JY Yang, W Xia, Y Wei, Y Liao, CJ Chang, Y Yang, CC Lai, ... Cancer research 68 (15), 6109-6117, 2008 | 217 | 2008 |