关注
Dirk Brockstedt
Dirk Brockstedt
RAPT Therapeutics, Inc.
在 rapt.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
PP Lee, C Yee, PA Savage, L Fong, D Brockstedt, JS Weber, D Johnson, ...
Nature medicine 5 (6), 677-685, 1999
13801999
Tumor-specific T cell dysfunction is a dynamic antigen-driven differentiation program initiated early during tumorigenesis
A Schietinger, M Philip, VE Krisnawan, EY Chiu, JJ Delrow, RS Basom, ...
Immunity 45 (2), 389-401, 2016
6872016
Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer
DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ...
Journal of clinical Oncology 33 (12), 1325-1333, 2015
6702015
Mice Lacking the Type I Interferon Receptor Are Resistant to Listeria monocytogenes
V Auerbuch, DG Brockstedt, N Meyer-Morse, M O'Riordan, DA Portnoy
The Journal of experimental medicine 200 (4), 527-533, 2004
5612004
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity
CW Chan, E Crafton, HN Fan, J Flook, K Yoshimura, M Skarica, ...
Nature medicine 12 (2), 207-213, 2006
5452006
Dendritic cells injected via different routes induce immunity in cancer patients
L Fong, D Brockstedt, C Benike, L Wu, EG Engleman
The Journal of Immunology 166 (6), 4254-4259, 2001
5002001
A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune …
DT Le, DG Brockstedt, R Nir-Paz, J Hampl, S Mathur, J Nemunaitis, ...
Clinical cancer research 18 (3), 858-868, 2012
3952012
Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy
L Fong, D Brockstedt, C Benike, JK Breen, G Strang, CL Ruegg, ...
The Journal of Immunology 167 (12), 7150-7156, 2001
3722001
Listeria-based cancer vaccines that segregate immunogenicity from toxicity
DG Brockstedt, MA Giedlin, ML Leong, KS Bahjat, Y Gao, W Luckett, ...
Proceedings of the National Academy of Sciences 101 (38), 13832-13837, 2004
3672004
Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide.
DT Kim, DJ Mitchell, DG Brockstedt, L Fong, GP Nolan, CG Fathman, ...
Journal of immunology (Baltimore, Md.: 1950) 159 (4), 1666-1668, 1997
2561997
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells
MV Goldberg, CH Maris, EL Hipkiss, AS Flies, L Zhen, RM Tuder, ...
Blood, The Journal of the American Society of Hematology 110 (1), 186-192, 2007
2522007
Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation
L Cohn, B Chatterjee, F Esselborn, A Smed-Sörensen, N Nakamura, ...
Journal of Experimental Medicine 210 (5), 1049-1063, 2013
2312013
Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration
DG Brockstedt, GM Podsakoff, L Fong, G Kurtzman, W Mueller-Ruchholtz, ...
Clinical Immunology 92 (1), 67-75, 1999
2051999
Results from a phase IIb, randomized, multicenter study of GVAX pancreas and CRS-207 compared with chemotherapy in adults with previously treated metastatic pancreatic …
DT Le, VJ Picozzi, AH Ko, ZA Wainberg, H Kindler, A Wang-Gillam, ...
Clinical Cancer Research 25 (18), 5493-5502, 2019
2022019
Induction of tissue-specific autoimmune prostatitis with prostatic acid phosphatase immunization: implications for immunotherapy of prostate cancer.
L Fong, CL Ruegg, D Brockstedt, EG Engleman, R Laus
Journal of immunology (Baltimore, Md.: 1950) 159 (7), 3113-3117, 1997
1881997
Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity
DG Brockstedt, KS Bahjat, MA Giedlin, W Liu, M Leong, W Luckett, Y Gao, ...
Nature medicine 11 (8), 853-860, 2005
1782005
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice
BP Keenan, Y Saenger, MI Kafrouni, A Leubner, P Lauer, A Maitra, ...
Gastroenterology 146 (7), 1784-1794. e6, 2014
1692014
Listeria monocytogenes as a vaccine vector: virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy
H Starks, KW Bruhn, H Shen, RA Barry, TW Dubensky, D Brockstedt, ...
The Journal of Immunology 173 (1), 420-427, 2004
1222004
Evaluation of cyclophosphamide/GVAX pancreas followed by listeria-mesothelin (CRS-207) with or without nivolumab in patients with pancreatic cancer
T Tsujikawa, T Crocenzi, JN Durham, EA Sugar, AA Wu, B Onners, ...
Clinical Cancer Research 26 (14), 3578-3588, 2020
1072020
Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4
LA Marshall, S Marubayashi, A Jorapur, S Jacobson, M Zibinsky, ...
Journal for immunotherapy of cancer 8 (2), 2020
1012020
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