The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 117 | 2021 |
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity Z Fan, JR Devlin, SJ Hogg, MA Doyle, PF Harrison, I Todorovski, ... Science advances 6 (18), eaaz5041, 2020 | 110 | 2020 |
H3K4me3 regulates RNA polymerase II promoter-proximal pause-release H Wang, Z Fan, PV Shliaha, M Miele, RC Hendrickson, X Jiang, K Helin Nature 615 (7951), 339-348, 2023 | 108 | 2023 |
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ... Molecular cell 81 (10), 2183-2200. e13, 2021 | 75 | 2021 |
Serine biosynthesis is a metabolic vulnerability in flt3-itd–driven acute myeloid leukemia S Bjelosevic, E Gruber, A Newbold, C Shembrey, JR Devlin, SJ Hogg, ... Cancer discovery 11 (6), 1582-1599, 2021 | 42 | 2021 |
Nono, a bivalent domain factor, regulates Erk signaling and mouse embryonic stem cell pluripotency C Ma, V Karwacki-Neisius, H Tang, W Li, Z Shi, H Hu, W Xu, Z Wang, ... Cell reports 17 (4), 997-1007, 2016 | 42 | 2016 |
An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions A Radzisheuskaya, I Peña‐Rømer, E Lorenzini, R Koche, Y Zhan, ... The EMBO Journal 42 (24), e114221, 2023 | 3 | 2023 |
A PP2A-Integrator complex fine-tunes transcription by opposing CDK9 SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, M Costacurta, ... BioRxiv, 2020.07. 12.199372, 2020 | 3 | 2020 |
RNA decay defines the response to transcriptional perturbation in leukaemia I Todorovski, B Feran, Z Fan, S Gadipally, D Yoannidis, IY Kong, ... bioRxiv, 2022.04. 06.487057, 2022 | | 2022 |