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| Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions VG Gorgoulis, LVF Vassiliou, P Karakaidos, P Zacharatos, A Kotsinas, ... Nature 434 (7035), 907-913, 2005 | 2431 | 2005 |
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| An oncogene-induced DNA damage model for cancer development TD Halazonetis, VG Gorgoulis, J Bartek science 319 (5868), 1352-1355, 2008 | 2176 | 2008 |
| c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities TD Halazonetis, K Georgopoulos, ME Greenberg, P Leder Cell 55 (5), 917-924, 1988 | 1339 | 1988 |
| Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53 NH Chehab, A Malikzay, M Appel, TD Halazonetis Genes & development 14 (3), 278-288, 2000 | 1192 | 2000 |
| p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks LB Schultz, NH Chehab, A Malikzay, TD Halazonetis The Journal of cell biology 151 (7), 1381-1390, 2000 | 1116 | 2000 |
| Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks Y Huyen, O Zgheib, RA DiTullio Jr, VG Gorgoulis, P Zacharatos, TJ Petty, ... Nature 432 (7015), 406-411, 2004 | 1109 | 2004 |
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| DNA replication stress as a hallmark of cancer M Macheret, TD Halazonetis Annual Review of Pathology: Mechanisms of Disease 10 (1), 425-448, 2015 | 796 | 2015 |
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| ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins MJF Waterman, ES Stavridi, JLF Waterman, TD Halazonetis Nature genetics 19 (2), 175-178, 1998 | 662 | 1998 |
| 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer RA DiTullio Jr, TA Mochan, M Venere, J Bartkova, M Sehested, J Bartek, ... Nature cell biology 4 (12), 998-1002, 2002 | 558 | 2002 |
| Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma SI Nikolaev, D Rimoldi, C Iseli, A Valsesia, D Robyr, C Gehrig, ... Nature genetics 44 (2), 133-139, 2012 | 499 | 2012 |
| Break-induced replication repair of damaged forks induces genomic duplications in human cells L Costantino, SK Sotiriou, JK Rantala, S Magin, E Mladenov, T Helleday, ... Science 343 (6166), 88-91, 2014 | 497 | 2014 |
| Chfr defines a mitotic stress checkpoint that delays entry into metaphase DM Scolnick, TD Halazonetis Nature 406 (6794), 430-435, 2000 | 490 | 2000 |
| Emerging common themes in regulation of PIKKs and PI3Ks H Lempiäinen, TD Halazonetis The EMBO journal 28 (20), 3067-3073, 2009 | 408 | 2009 |
| Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress M Macheret, TD Halazonetis Nature 555 (7694), 112-116, 2018 | 379 | 2018 |
| SCFβTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response A Peschiaroli, NV Dorrello, D Guardavaccaro, M Venere, T Halazonetis, ... Molecular cell 23 (3), 319-329, 2006 | 337 | 2006 |
