Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells CL Scott, F Zheng, P De Baetselier, L Martens, Y Saeys, S De Prijck, ... Nature communications 7 (1), 10321, 2016 | 763 | 2016 |
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment H Van Hove, L Martens, I Scheyltjens, K De Vlaminck, AR Pombo Antunes, ... Nature neuroscience 22 (6), 1021-1035, 2019 | 689 | 2019 |
Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages L van de Laar, W Saelens, S De Prijck, L Martens, CL Scott, ... Immunity 44 (4), 755-768, 2016 | 627 | 2016 |
Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche J Bonnardel, W T’Jonck, D Gaublomme, R Browaeys, CL Scott, L Martens, ... Immunity 51 (4), 638-654. e9, 2019 | 454 | 2019 |
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches M Guilliams, J Bonnardel, B Haest, B Vanderborght, C Wagner, ... Cell 185 (2), 379-396. e38, 2022 | 433 | 2022 |
Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver A Remmerie, L Martens, T Thoné, A Castoldi, R Seurinck, B Pavie, ... Immunity 53 (3), 641-657. e14, 2020 | 360 | 2020 |
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization AR Pombo Antunes, I Scheyltjens, F Lodi, J Messiaen, A Antoranz, ... Nature neuroscience 24 (4), 595-610, 2021 | 338 | 2021 |
IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively D Sichien, CL Scott, L Martens, M Vanderkerken, S Van Gassen, ... Immunity 45 (3), 626-640, 2016 | 327 | 2016 |
Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection C Bosteels, K Neyt, M Vanheerswynghels, MJ van Helden, D Sichien, ... Immunity 52 (6), 1039-1056. e9, 2020 | 308 | 2020 |
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells F Osorio, SJ Tavernier, E Hoffmann, Y Saeys, L Martens, J Vetters, ... Nature immunology 15 (3), 248-257, 2014 | 253 | 2014 |
The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages CL Scott, W T’Jonck, L Martens, H Todorov, D Sichien, B Soen, ... Immunity 49 (2), 312-325. e5, 2018 | 205 | 2018 |
Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells CA Tibbitt, JM Stark, L Martens, J Ma, JE Mold, K Deswarte, G Oliynyk, ... Immunity 51 (1), 169-184. e5, 2019 | 199 | 2019 |
Passenger mutations confound interpretation of all genetically modified congenic mice TV Berghe, P Hulpiau, L Martens, RE Vandenbroucke, ... Immunity 43 (1), 200-209, 2015 | 186 | 2015 |
Nlrp6-and ASC-dependent inflammasomes do not shape the commensal gut microbiota composition M Mamantopoulos, F Ronchi, F Van Hauwermeiren, S Vieira-Silva, ... Immunity 47 (2), 339-348. e4, 2017 | 176 | 2017 |
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury E Ydens, L Amann, B Asselbergh, CL Scott, L Martens, D Sichien, ... Nature neuroscience 23 (5), 676-689, 2020 | 172 | 2020 |
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients K Venken, P Jacques, C Mortier, ME Labadia, T Decruy, J Coudenys, ... Nature communications 10 (1), 9, 2019 | 166 | 2019 |
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2 CL Scott, B Soen, L Martens, N Skrypek, W Saelens, J Taminau, ... Journal of Experimental Medicine 213 (6), 897-911, 2016 | 155 | 2016 |
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy H Van Damme, B Dombrecht, M Kiss, H Roose, E Allen, E Van Overmeire, ... Journal for immunotherapy of cancer 9 (2), 2021 | 117 | 2021 |
Myocardial infarction primes autoreactive T cells through activation of dendritic cells K Van der Borght, CL Scott, V Nindl, A Bouche, L Martens, D Sichien, ... Cell reports 18 (12), 3005-3017, 2017 | 116 | 2017 |
TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine CC Bain, J Montgomery, CL Scott, JM Kel, MJH Girard-Madoux, L Martens, ... Nature communications 8 (1), 620, 2017 | 101 | 2017 |